LOCUS       SIT99533.1               257 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Putative
            hydroxylase protein.
ACCESSION   LT708304-945
PROTEIN_ID  SIT99533.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0935"
                     /note="Mb0935, -, len: 257 aa. Equivalent to Rv0911, len:
                     257 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 257 aa overlap). Conserved hypothetical
                     protein, showing similarity with hydroxylases and
                     hypothetical proteins e.g. T35325 probable hydroxylase
                     from Streptomyces coelicolor (265 aa); Q54242 hypothetical
                     protein from Streptomyces, FASTA scores: opt: 372, E():
                     8.8e-18, (32.0% identity in 256 aa overlap);
                     AAD04716.1|U77891 doxorubicin biosynthesis enzyme DnrV
                     from Streptomyces peucetius (275 aa); AAA63051.1|U15184
                     hypothetical protein from Mycobacterium leprae (94 aa);
                     etc. Also similar to Rv0577 HYPOTHETICAL PROTEIN from
                     Mycobacterium tuberculosis (261 aa). Protein product from
                     Mb0935 detected using shotgun mass spectrometry and SWATH
                     mass spectrometry. Mb0935 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="InterPro:IPR029068"
                     /db_xref="InterPro:IPR037523"
                     /db_xref="InterPro:IPR041581"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XXS1"
BEGIN
        1 MPTRSSAPLG APCWIDLTTS DVDRAQDFYG TVFGWAFESA GPDYGGYINA AKGGHPVAGL
       61 MANRPEFQSP DGWATYFHTV DIGATVAKLA AAGGSSCLDP MEVPGKGFMS LAVDPSGAAF
      121 GLWQPLQHHG FEVIGEAGSP VWHQLTTRDY RSVIDFYRQV FGWRTEQISD TDEFCYTTAW
      181 FDDQQLLGVM DGSSCLPEGV PSNWTIFFGA EDVDETLRVI CDNGGSVVRA AENTPYGRLA
      241 AAADPMGVVF NLSSLQA
//