LOCUS SIT99533.1 257 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Putative hydroxylase protein. ACCESSION LT708304-945 PROTEIN_ID SIT99533.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB0935" /note="Mb0935, -, len: 257 aa. Equivalent to Rv0911, len: 257 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 257 aa overlap). Conserved hypothetical protein, showing similarity with hydroxylases and hypothetical proteins e.g. T35325 probable hydroxylase from Streptomyces coelicolor (265 aa); Q54242 hypothetical protein from Streptomyces, FASTA scores: opt: 372, E(): 8.8e-18, (32.0% identity in 256 aa overlap); AAD04716.1|U77891 doxorubicin biosynthesis enzyme DnrV from Streptomyces peucetius (275 aa); AAA63051.1|U15184 hypothetical protein from Mycobacterium leprae (94 aa); etc. Also similar to Rv0577 HYPOTHETICAL PROTEIN from Mycobacterium tuberculosis (261 aa). Protein product from Mb0935 detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb0935 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="InterPro:IPR029068" /db_xref="InterPro:IPR037523" /db_xref="InterPro:IPR041581" /db_xref="UniProtKB/TrEMBL:A0A1R3XXS1" BEGIN 1 MPTRSSAPLG APCWIDLTTS DVDRAQDFYG TVFGWAFESA GPDYGGYINA AKGGHPVAGL 61 MANRPEFQSP DGWATYFHTV DIGATVAKLA AAGGSSCLDP MEVPGKGFMS LAVDPSGAAF 121 GLWQPLQHHG FEVIGEAGSP VWHQLTTRDY RSVIDFYRQV FGWRTEQISD TDEFCYTTAW 181 FDDQQLLGVM DGSSCLPEGV PSNWTIFFGA EDVDETLRVI CDNGGSVVRA AENTPYGRLA 241 AAADPMGVVF NLSSLQA //