LOCUS       SIT99515.1               325 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 possible
            s-adenosylmethionine-dependent methyltransferase protein.
ACCESSION   LT708304-927
PROTEIN_ID  SIT99515.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0917C"
                     /note="Mb0917c, -, len: 325 aa. Equivalent to Rv0893c,
                     len: 325 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 325 aa overlap). Conserved
                     hypothetical protein, belongs in family with
                     P96823|Rv0146|MTCI5.20 CONSERVED HYPOTHETICAL PROTEIN from
                     Mycobacterium tuberculosis (310 aa), FASTA scores: opt:
                     784, E(): 0, (43.2% identity in 308 aa overlap); Rv0726c,
                     Rv0731c, Rv3399, etc. Also shows some similarity with
                     others e.g. SC9B5.10|T35930 hypothetical protein from
                     Streptomyces coelicolor (303 aa); BSUB0008_141|Q45500
                     HYPOTHETICAL 34.8 KD PROTEIN from Bacillus subtilis (304
                     aa), FASTA scores: E(): 0.00033, (26.8% identity in 168 aa
                     overlap); etc. Protein product from Mb0917c detected using
                     SWATH mass spectrometry. Mb0917c found to be expressed
                     during exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:P64748"
                     /db_xref="InterPro:IPR007213"
                     /db_xref="InterPro:IPR011610"
                     /db_xref="InterPro:IPR029063"
                     /db_xref="UniProtKB/Swiss-Prot:P64748"
BEGIN
        1 MRTEDDSWDV TTSVGSTGLL VAAARALETQ KADPLAIDPY AEVFCRAAGG EWADVLDGKL
       61 PDHYLTTGDF GEHFVNFQGA RTRYFDEYFS RATAAGMKQV VILAAGLDSR AFRLQWPIGT
      121 TIFELDRPQV LDFKNAVLAD YHIRPRAQRR SVAVDLRDEW QIALCNNGFD ANRPSAWIAE
      181 GLLVYLSAEA QQRLFIGIDT LASPGSHVAV EEATPLDPCE FAAKLERERA ANAQGDPRRF
      241 FQMVYNERWA RATEWFDERG WRATATPLAE YLRRVGRAVP EADTEAAPMV TAITFVSAVR
      301 TGLVADPART SPSSTSIGFK RFEAD
//