LOCUS       SIT99513.1               285 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE
            TRANSCRIPTIONAL REGULATORY PROTEIN protein.
ACCESSION   LT708304-925
PROTEIN_ID  SIT99513.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0915C"
                     /note="Mb0915c, -, len: 285 aa. Equivalent to Rv0891c,
                     len: 285 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.6% identity in 285 aa overlap). Possible
                     transcriptional regulator, highly similar in N-terminus to
                     NP_302202.1|NC_002677 possible transcriptional regulator
                     from Mycobacterium leprae (1106 aa). Also highly similar
                     to several Mycobacterium tuberculosis putative
                     transcriptional regulators e.g. Q1102|MTCY02B10_22
                     PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (1159 aa),
                     FASTA scores: opt: 702, E(): 8.3e-40, (50.6% identity in
                     247 aa overlap); MTV036_21; MTV008_44; MTCY02B10_23. Also
                     shows similarity with several adenylate cyclases and
                     hydrolases from other organisms. Mb0915c found to be
                     expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="GOA:P59970"
                     /db_xref="InterPro:IPR001054"
                     /db_xref="InterPro:IPR029787"
                     /db_xref="UniProtKB/Swiss-Prot:P59970"
BEGIN
        1 MLFNAVHNSL PPNIDIDHAI LRGEDHPPTC AKCVARGRIS ALGSLDLRYH SLRCYAAPPD
       61 VGRCEFVPPR RRVLIANQGL DVSRLPPTGT VTLLLADVEE STHLWQMCPE DMATAIAHLD
      121 HTVSEAITNH GGVQPVKRYE GDSFVAAFTR ASDAAACALD LQRTSLAPIR LRIGLHTGEV
      181 QLRDELYVGP TINRTARLRD LAHGGQVVLS AATGDLVTGR LPADAWLVDL GRHPLRGLPR
      241 PEWVMQLCHP DIREKFPPLR TAKSSPTSIL PAQFTTFVGR RAQIS
//