LOCUS SIT99513.1 285 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN protein. ACCESSION LT708304-925 PROTEIN_ID SIT99513.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB0915C" /note="Mb0915c, -, len: 285 aa. Equivalent to Rv0891c, len: 285 aa, from Mycobacterium tuberculosis strain H37Rv, (99.6% identity in 285 aa overlap). Possible transcriptional regulator, highly similar in N-terminus to NP_302202.1|NC_002677 possible transcriptional regulator from Mycobacterium leprae (1106 aa). Also highly similar to several Mycobacterium tuberculosis putative transcriptional regulators e.g. Q1102|MTCY02B10_22 PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (1159 aa), FASTA scores: opt: 702, E(): 8.3e-40, (50.6% identity in 247 aa overlap); MTV036_21; MTV008_44; MTCY02B10_23. Also shows similarity with several adenylate cyclases and hydrolases from other organisms. Mb0915c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:P59970" /db_xref="InterPro:IPR001054" /db_xref="InterPro:IPR029787" /db_xref="UniProtKB/Swiss-Prot:P59970" BEGIN 1 MLFNAVHNSL PPNIDIDHAI LRGEDHPPTC AKCVARGRIS ALGSLDLRYH SLRCYAAPPD 61 VGRCEFVPPR RRVLIANQGL DVSRLPPTGT VTLLLADVEE STHLWQMCPE DMATAIAHLD 121 HTVSEAITNH GGVQPVKRYE GDSFVAAFTR ASDAAACALD LQRTSLAPIR LRIGLHTGEV 181 QLRDELYVGP TINRTARLRD LAHGGQVVLS AATGDLVTGR LPADAWLVDL GRHPLRGLPR 241 PEWVMQLCHP DIREKFPPLR TAKSSPTSIL PAQFTTFVGR RAQIS //