LOCUS SIT99495.1 650 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE ACYL-COA DEHYDROGENASE FADE10 protein. ACCESSION LT708304-907 PROTEIN_ID SIT99495.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="fadE10" /locus_tag="BQ2027_MB0897" /note="Mb0897, fadE10, len: 650 aa. Equivalent to Rv0873, len: 650 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 650 aa overlap). Probable fadE10, acyl-CoA dehydrogenase (EC 1.3.99.-), highly similar to many e.g. CAB91129.1|AL355913 putative acyl CoA dehydrogenase from Streptomyces coelicolor (658 aa); P50544|ACDV_MOUSE ACYL-COA DEHYDROGENASE from Mus musculus (656 aa); D30647|RATVLCAD_1 very-long-chain Acyl-CoA dehydrogenase from Rattus norvegicus (655 aa), FASTA scores: opt: 675, E(): 0, (33.9% identity in 380 aa overlap); etc. Protein product from Mb0897 detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb0897 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:P63430" /db_xref="InterPro:IPR006091" /db_xref="InterPro:IPR009075" /db_xref="InterPro:IPR009100" /db_xref="InterPro:IPR013786" /db_xref="InterPro:IPR036250" /db_xref="InterPro:IPR037069" /db_xref="UniProtKB/Swiss-Prot:P63430" /experiment="experimental evidence, no additional details recorded" BEGIN 1 MAQQTQVTEE QARALAEESR ESGWDKPSFA KELFLGRFPL GLIHPFPKPS DAEEARTEAF 61 LVKLREFLDT VDGSVIERAA QIPDEYVKGL AELGCFGLKI PSEYGGLNMS QVAYNRVLMM 121 VTTVHSSLGA LLSAHQSIGV PEPLKLAGTA EQKRRFLPRC AAGAISAFLL TEPDVGSDPA 181 RMASTATPID DGQAYELEGV KLWTTNGVVA DLLVVMARVP RSEGHRGGIS AFVVEADSPG 241 ITVERRNKFM GLRGIENGVT RLHRVRVPKD NLIGREGDGL KIALTTLNAG RLSLPAIATG 301 VAKQALKIAR EWSVERVQWG KPVGQHEAVA SKISFIAATN YALDAVVELS SQMADEGRND 361 IRIEAALAKL WSSEMACLVG DELLQIRGGR GYETAESLAA RGERAVPVEQ MVRDLRINRI 421 FEGSSEIMRL LIAREAVDAH LTAAGDLANP KADLRQKAAA AAGASGFYAK WLPKLVFGEG 481 QLPTTYREFG ALATHLRFVE RSSRKLARNT FYGMARWQAS LEKKQGFLGR IVDIGAELFA 541 ISAACVRAEA QRTADPVEGE QAYELAEAFC QQATLRVEAL FDALWSNTDS IDVRLANDVL 601 EGRYTWLEQG ILDQSEGTGP WIASWEPGPS TEANLARRFL TVSPSSEAKL //