LOCUS       SIT99471.1               419 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            CONSERVED INTEGRAL MEMBRANE TRANSPORT PROTEIN protein.
ACCESSION   LT708304-883
PROTEIN_ID  SIT99471.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0872"
                     /note="Mb0872, -, len: 419 aa. Equivalent to Rv0849, len:
                     419 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 419 aa overlap). Probable conserved
                     integral membrane transport protein, possibly member of
                     major facilitator superfamily (MFS) involved in transport
                     of drug, showing similarity with others e.g. T35055
                     probable transport system permease protein from
                     Streptomyces coelicolor (436 aa); NP_295031.1|NC_001263
                     major facilitator family protein from Deinococcus
                     radiodurans (458 aa); NP_455659.1|NC_003198 putative
                     membrane transporter from Salmonella enterica subsp.
                     enterica serovar Typhi (402 aa); etc. Protein product from
                     Mb0872 detected using SWATH mass spectrometry."
                     /db_xref="GOA:A0A1R3XWL5"
                     /db_xref="InterPro:IPR011701"
                     /db_xref="InterPro:IPR020846"
                     /db_xref="InterPro:IPR036259"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XWL5"
BEGIN
        1 MGARAIFRGF NRPSRVLMIN QFGINIGFYM LMPYLADYLA GPLGLAAWAV GLVMGVRNFS
       61 QQGMFFVGGT LADRFGYKPL IIAGCLIRTG GFALLVVAQS LPSVLIAAAA TGFAGALFNP
      121 AVRGYLAAEA GERKIEAFAM FNVFYQSGIL LGPLVGLVLL ALDFRITVLA AAGVFGLLTV
      181 AQLVALPQHR ADSEREKTSI LQDWRVVVRN RPFLTLAAAM TGCYALSFQI YLALPMQASI
      241 LMPRNQYLLI AAMFAVSGLV AVGGQLRITR WFAVRWGAER SLVVGATILA ASFIPVAVIP
      301 NGQRFGVAVA VMALVLSASL LAVASAALFP FEMRAVVALS GDRLVATHYG FYSTIVGVGV
      361 LVGNLAIGSL MSAARRLNTD EIVWGGLILV GIVAVAGLRR LDTFTSGSQN MTGRWAAPR
//