LOCUS SIT99471.1 419 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE CONSERVED INTEGRAL MEMBRANE TRANSPORT PROTEIN protein. ACCESSION LT708304-883 PROTEIN_ID SIT99471.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB0872" /note="Mb0872, -, len: 419 aa. Equivalent to Rv0849, len: 419 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 419 aa overlap). Probable conserved integral membrane transport protein, possibly member of major facilitator superfamily (MFS) involved in transport of drug, showing similarity with others e.g. T35055 probable transport system permease protein from Streptomyces coelicolor (436 aa); NP_295031.1|NC_001263 major facilitator family protein from Deinococcus radiodurans (458 aa); NP_455659.1|NC_003198 putative membrane transporter from Salmonella enterica subsp. enterica serovar Typhi (402 aa); etc. Protein product from Mb0872 detected using SWATH mass spectrometry." /db_xref="GOA:A0A1R3XWL5" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="UniProtKB/TrEMBL:A0A1R3XWL5" BEGIN 1 MGARAIFRGF NRPSRVLMIN QFGINIGFYM LMPYLADYLA GPLGLAAWAV GLVMGVRNFS 61 QQGMFFVGGT LADRFGYKPL IIAGCLIRTG GFALLVVAQS LPSVLIAAAA TGFAGALFNP 121 AVRGYLAAEA GERKIEAFAM FNVFYQSGIL LGPLVGLVLL ALDFRITVLA AAGVFGLLTV 181 AQLVALPQHR ADSEREKTSI LQDWRVVVRN RPFLTLAAAM TGCYALSFQI YLALPMQASI 241 LMPRNQYLLI AAMFAVSGLV AVGGQLRITR WFAVRWGAER SLVVGATILA ASFIPVAVIP 301 NGQRFGVAVA VMALVLSASL LAVASAALFP FEMRAVVALS GDRLVATHYG FYSTIVGVGV 361 LVGNLAIGSL MSAARRLNTD EIVWGGLILV GIVAVAGLRR LDTFTSGSQN MTGRWAAPR //