LOCUS       SIT99454.1               137 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 pe-
            pgrs family protein pe_pgrs12 protein.
ACCESSION   LT708304-866
PROTEIN_ID  SIT99454.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="PE_PGRS12"
                     /locus_tag="BQ2027_MB0855"
                     /note="Mb0855, PE_PGRS12, len: 137 aa. Equivalent to
                     Rv0832, len: 137 aa, from Mycobacterium tuberculosis
                     strain H37Rv, (100.0% identity in 137 aa overlap). Member
                     of the Mycobacterium tuberculosis PE family, possibly PGRS
                     subfamily of gly-rich proteins, highly similar to many
                     others e.g. MTCY1A11.25c|Z78020 (498 aa), FASTA scores:
                     opt: 529, E(): 5.2e-22, (61.8% identity in 136 aa
                     overlap); etc. Appears to have incurred frameshift as next
                     ORF should be continuation; sequence has been checked but
                     no error found. Mb0855 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="InterPro:IPR000084"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XWM1"
BEGIN
        1 MSYVSVLPAT LATAATEVAR IGSALSLASA VAAAQTSAVQ AAAADEVSAA IAALFSAHGR
       61 DFQALSARAA AFHHEFVQAL AAGAGSYAVA EIAAASPLQS LIDVFNAPIQ AATGRPLIGN
      121 GANGQPGTGA PGGPAGG
//