LOCUS SIT99454.1 137 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 pe- pgrs family protein pe_pgrs12 protein. ACCESSION LT708304-866 PROTEIN_ID SIT99454.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="PE_PGRS12" /locus_tag="BQ2027_MB0855" /note="Mb0855, PE_PGRS12, len: 137 aa. Equivalent to Rv0832, len: 137 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 137 aa overlap). Member of the Mycobacterium tuberculosis PE family, possibly PGRS subfamily of gly-rich proteins, highly similar to many others e.g. MTCY1A11.25c|Z78020 (498 aa), FASTA scores: opt: 529, E(): 5.2e-22, (61.8% identity in 136 aa overlap); etc. Appears to have incurred frameshift as next ORF should be continuation; sequence has been checked but no error found. Mb0855 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="InterPro:IPR000084" /db_xref="UniProtKB/TrEMBL:A0A1R3XWM1" BEGIN 1 MSYVSVLPAT LATAATEVAR IGSALSLASA VAAAQTSAVQ AAAADEVSAA IAALFSAHGR 61 DFQALSARAA AFHHEFVQAL AAGAGSYAVA EIAAASPLQS LIDVFNAPIQ AATGRPLIGN 121 GANGQPGTGA PGGPAGG //