LOCUS       SIT99448.1               351 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 CONSERVED
            HYPOTHETICAL PROTEIN protein.
ACCESSION   LT708304-860
PROTEIN_ID  SIT99448.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0849"
                     /note="Mb0849, -, len: 351 aa. Equivalent to Rv0826, len:
                     351 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.4% identity in 351 aa overlap). Conserved hypothetical
                     protein, similar to CAB94053.1|AL358672|SC7A12.06
                     hypothetical protein from Streptomyces coelicolor (300
                     aa); and NP_421372.1|NC_002696 hypothetical protein from
                     Caulobacter crescentus (299 aa). Also similar to other
                     proteins from Mycobacterium tuberculosis e.g.
                     Rv1645c|Z85982|MTCY06H11.09 (351 aa), FASTA scores: opt:
                     1199, E(): 0, (57.5% identity in 299 aa overlap); Rv2237;
                     Rv0276; etc. Mb0849 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="InterPro:IPR018713"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XWI6"
BEGIN
        1 MTQDTSATCP LTSTVQDSSP VAGQLGRPIG FRGLAGGCPV SPLGYESPPL PLGPDSLTWR
       61 YFGDWRGMLQ GPWAGSMQNM HPQLGAAVED HSTFFRGRWP RLLRSLYPIG GVVFDGDRAP
      121 VTGVQVRDYH ITIKGVDGAG RRYHALNPDV FYWAHATFFV GTLHVAERFC GGLTEAQRRQ
      181 LFDEHVQWYR MYGMSMRPVP ATWEEFQDYW DHMCRNVLEN NFAARAVLDL TELPKPPFAQ
      241 RVPDWLWAAP RKLLARFFVW LTVGLYDPPV RELMGYRWLR RDEWLHRRFG DIVQLVFALV
      301 PFRFRKHPRA RAGWDRATGR IPADAPLVQT PARNLPPPDE RDNPTHYCPK V
//