LOCUS SIT99447.1 213 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Transcriptional regulator, AcrR family protein. ACCESSION LT708304-859 PROTEIN_ID SIT99447.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB0848C" /note="Mb0848c, -, len: 213 aa. Equivalent to Rv0825c, len: 213 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 213 aa overlap). Conserved hypothetical protein, highly similar, but in part (between aa ~43-96) to fadD27|Rv0275c|MTV035.03 PUTATIVE FATTY-ACID-COA LIGASE from Mycobacterium tuberculosis (241 aa), FASTA scores: E(): 7.3e-09, (32.6% identity in 190 aa overlap). Also shows similarity with other proteins from Mycobacterium tuberculosis e.g. Rv0078|AL0214|MTV030_22 (201 aa), FASTA scores: opt:118, E(): 0.32, (34.5% identity in 113 aa overlap); etc. Protein product from Mb0848c detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb0848c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3XWJ9" /db_xref="InterPro:IPR001647" /db_xref="InterPro:IPR009057" /db_xref="UniProtKB/TrEMBL:A0A1R3XWJ9" BEGIN 1 MQTGQNRGRW SGVPLESRHA LRRDNLVAAG VQLLGGAGGP ALTVRAVCRH AGLTERYFYE 61 SFADREHFVR AVYDDVCTRA MATLTSAQTP REAVEQFVEL MVDDPVRGRV LLLAPAVEPA 121 LTRSGAEWMP NFIELLQRKL SRIVDPVLQK LVATSLIGAL TGLFTAYLNG RLGATRKQFI 181 DYCVNMLLST AATYAPHRER GESEHSIPAG PHN //