LOCUS       SIT99447.1               213 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Transcriptional
            regulator, AcrR family protein.
ACCESSION   LT708304-859
PROTEIN_ID  SIT99447.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0848C"
                     /note="Mb0848c, -, len: 213 aa. Equivalent to Rv0825c,
                     len: 213 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 213 aa overlap). Conserved
                     hypothetical protein, highly similar, but in part (between
                     aa ~43-96) to fadD27|Rv0275c|MTV035.03 PUTATIVE
                     FATTY-ACID-COA LIGASE from Mycobacterium tuberculosis (241
                     aa), FASTA scores: E(): 7.3e-09, (32.6% identity in 190 aa
                     overlap). Also shows similarity with other proteins from
                     Mycobacterium tuberculosis e.g. Rv0078|AL0214|MTV030_22
                     (201 aa), FASTA scores: opt:118, E(): 0.32, (34.5%
                     identity in 113 aa overlap); etc. Protein product from
                     Mb0848c detected using shotgun mass spectrometry and SWATH
                     mass spectrometry. Mb0848c found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:A0A1R3XWJ9"
                     /db_xref="InterPro:IPR001647"
                     /db_xref="InterPro:IPR009057"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XWJ9"
BEGIN
        1 MQTGQNRGRW SGVPLESRHA LRRDNLVAAG VQLLGGAGGP ALTVRAVCRH AGLTERYFYE
       61 SFADREHFVR AVYDDVCTRA MATLTSAQTP REAVEQFVEL MVDDPVRGRV LLLAPAVEPA
      121 LTRSGAEWMP NFIELLQRKL SRIVDPVLQK LVATSLIGAL TGLFTAYLNG RLGATRKQFI
      181 DYCVNMLLST AATYAPHRER GESEHSIPAG PHN
//