LOCUS       SIT99415.1               269 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY GNTR-FAMILY)
            protein.
ACCESSION   LT708304-827
PROTEIN_ID  SIT99415.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0816C"
                     /note="Mb0816c, -, len: 269 aa. Equivalent to Rv0792c,
                     len: 269 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 269 aa overlap). Probable
                     transcriptional regulator, GntR-family, similar to many
                     others of GntR family e.g. BSUB0018_189|Z99121 from
                     Bacillus subtilis (243 aa), FASTA scores: opt: 367, E():
                     1.5e-17, (32.1% identity in 246 aa overlap);
                     P31453|YIDP_ECOLI from Escherichia coli (238 aa), FASTA
                     scores: opt: 236, E(): 8.8e-09, (26.4% identity in 235 aa
                     overlap); etc. Protein product from Mb0816c detected using
                     SWATH mass spectrometry. Mb0816c found to be expressed
                     during exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:A0A1R3XWU6"
                     /db_xref="InterPro:IPR000524"
                     /db_xref="InterPro:IPR011663"
                     /db_xref="InterPro:IPR028978"
                     /db_xref="InterPro:IPR036388"
                     /db_xref="InterPro:IPR036390"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XWU6"
BEGIN
        1 MTSVKLDLDA ADLRISRGSV PASTQLAEAL KAQIIQQRLP RGGRLPSERE LIDRSGLSRV
       61 TVRAAVGMLQ RQGWLVRRQG LGTFVADPVE QELSCGVRTI TEVLLSCGVT PQVDVLSHQT
      121 GPAPQRISET LGLVEVLCIR RRIRTGDQPL ALVTAYLPPG VGPAVEPLLS GSADTETTYA
      181 MWERRLGVRI AQATHEIHAA GASPDVADAL GLAVGSPVLV VDRTSYTNDG KPLEVVVFHH
      241 RPERYQFSVT LPRTLPGSGA GIIEKRDFA
//