LOCUS       SIT99373.1               390 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            ACYL-COA DEHYDROGENASE FADE9 protein.
ACCESSION   LT708304-785
PROTEIN_ID  SIT99373.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="fadE9"
                     /locus_tag="BQ2027_MB0774C"
                     /note="Mb0774c, fadE9, len: 390 aa. Equivalent to Rv0752c,
                     len: 390 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.5% identity in 390 aa overlap). Probable fadE9,
                     acyl-CoA dehydrogenase (EC 1.3.99.-), highly similar to
                     many e.g. NP_437985.1|NC_003078 putative acyl-CoA
                     dehydrogenase protein from Sinorhizobium meliloti (380
                     aa); Z99123|BSUB0020_14 from Bacillus subtilis (379 aa),
                     FASTA scores: opt: 853, E(): 0, (39.8% identity in 384 aa
                     overlap); etc. Contains PS00072 Acyl-CoA dehydrogenases
                     signature 1, and PS00073 Acyl-Co Adehydrogenases signature
                     2. BELONGS TO THE ACYL-COA DEHYDROGENASES FAMILY. Protein
                     product from Mb0774c detected using SWATH mass
                     spectrometry. Mb0774c found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:A0A1R3XXB2"
                     /db_xref="InterPro:IPR006089"
                     /db_xref="InterPro:IPR006091"
                     /db_xref="InterPro:IPR009075"
                     /db_xref="InterPro:IPR009100"
                     /db_xref="InterPro:IPR013786"
                     /db_xref="InterPro:IPR036250"
                     /db_xref="InterPro:IPR037069"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XXB2"
BEGIN
        1 MFVLNDDERV IVETAAAFAG KRLAPHALEW DAAKHFPVDV LREAAELGMA AIYCRDDVGG
       61 SGLRRLDGAR IFEQLAIADP VTAAFLSIHN MCAWMIDSFG TDEQRKDWIP RLATMGVIAS
      121 YCLTEPGAGS DAGALSTRAV RHGSGKGGDY VLDGVKQFIS GAAASDVYVV MARTGAEGPR
      181 GVSAFVVEKG TPGLSFGAPE AKMGWHAQPT AQVVLDGVRV PAEAMLGGAD GEGAGFGIAM
      241 SGLNGGRLNI AACSLGGAQA AFDKAGAYVR DRQAFGGSLL DEPTVRFTLA DMATGLQTSR
      301 MLLWRAASAL DDDDADKVEL CAMAKRYVTD TCFEVADQAL QLHGGYGYLR EYGLEKIVRD
      361 LRVHRILEGT NEIMRLVIGR AEAARFRATV
//