LOCUS SIT99373.1 390 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE ACYL-COA DEHYDROGENASE FADE9 protein. ACCESSION LT708304-785 PROTEIN_ID SIT99373.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="fadE9" /locus_tag="BQ2027_MB0774C" /note="Mb0774c, fadE9, len: 390 aa. Equivalent to Rv0752c, len: 390 aa, from Mycobacterium tuberculosis strain H37Rv, (99.5% identity in 390 aa overlap). Probable fadE9, acyl-CoA dehydrogenase (EC 1.3.99.-), highly similar to many e.g. NP_437985.1|NC_003078 putative acyl-CoA dehydrogenase protein from Sinorhizobium meliloti (380 aa); Z99123|BSUB0020_14 from Bacillus subtilis (379 aa), FASTA scores: opt: 853, E(): 0, (39.8% identity in 384 aa overlap); etc. Contains PS00072 Acyl-CoA dehydrogenases signature 1, and PS00073 Acyl-Co Adehydrogenases signature 2. BELONGS TO THE ACYL-COA DEHYDROGENASES FAMILY. Protein product from Mb0774c detected using SWATH mass spectrometry. Mb0774c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3XXB2" /db_xref="InterPro:IPR006089" /db_xref="InterPro:IPR006091" /db_xref="InterPro:IPR009075" /db_xref="InterPro:IPR009100" /db_xref="InterPro:IPR013786" /db_xref="InterPro:IPR036250" /db_xref="InterPro:IPR037069" /db_xref="UniProtKB/TrEMBL:A0A1R3XXB2" BEGIN 1 MFVLNDDERV IVETAAAFAG KRLAPHALEW DAAKHFPVDV LREAAELGMA AIYCRDDVGG 61 SGLRRLDGAR IFEQLAIADP VTAAFLSIHN MCAWMIDSFG TDEQRKDWIP RLATMGVIAS 121 YCLTEPGAGS DAGALSTRAV RHGSGKGGDY VLDGVKQFIS GAAASDVYVV MARTGAEGPR 181 GVSAFVVEKG TPGLSFGAPE AKMGWHAQPT AQVVLDGVRV PAEAMLGGAD GEGAGFGIAM 241 SGLNGGRLNI AACSLGGAQA AFDKAGAYVR DRQAFGGSLL DEPTVRFTLA DMATGLQTSR 301 MLLWRAASAL DDDDADKVEL CAMAKRYVTD TCFEVADQAL QLHGGYGYLR EYGLEKIVRD 361 LRVHRILEGT NEIMRLVIGR AEAARFRATV //