LOCUS       SIT99360.1               175 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 CONSERVED
            HYPOTHETICAL PROTEIN protein.
ACCESSION   LT708304-772
PROTEIN_ID  SIT99360.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0761"
                     /note="Mb0761, -, len: 175 aa. Equivalent to Rv0740, len:
                     175 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 175 aa overlap). Conserved
                     hypothetical protein; C-terminus (possibly part of
                     truncated IS1557) shows nearly perfect identity to
                     Rv0750|MTV041_24 (81 aa), FASTA score: (92.6% identity in
                     81 aa overlap). Also shows weak similarity to MTV007_5
                     hypothetical protein from Mycobacterium tuberculosis (313
                     aa), FASTA score: (34.5% identity in 110 aa overlap); and
                     MLCL536_27 hypothetical protein from Mycobacterium leprae
                     (315 aa), FASTA score: (34.5% identity in 84 aa overlap).
                     Protein product from Mb0761 detected using SWATH mass
                     spectrometry. Mb0761 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XW86"
BEGIN
        1 MLPKNTRPTS ETAEEFWDNS LWCSWGDRET GYTRTVTVSI CQVADGEREA EGVRDMMRLE
       61 CPAGLDLRTP NPEAYEITGQ RPGEFVFVLG YLGHVRAIVG NCYIEIMPMG TRVELSKLAD
      121 VALDIGRSVG CSAYENDFTL PDIPTQWRNQ PLGWYTQGLA PYLPGLSDPK DAAEG
//