LOCUS       SIT99354.1               266 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 methionine
            aminopeptidase mapa (map) (peptidase m) (metap) protein.
ACCESSION   LT708304-766
PROTEIN_ID  SIT99354.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="mapA"
                     /locus_tag="BQ2027_MB0755"
                     /note="Mb0755, mapA, len: 266 aa. Equivalent to Rv0734,
                     len: 266 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 266 aa overlap). Probable mapA,
                     methionine aminopeptidase (map) (EC 3.4.11.18), equivalent
                     to Z98756|MLCB2492_29 probable methionine aminopeptidase
                     from Mycobacterium leprae (266 aa), FASTA scores: opt:
                     1717, E(): 0, (83.4% identity in 265 aa overlap). Also
                     highly similar to many e.g. T35553 methionine
                     aminopeptidase from Streptomyces coelicolor (278 aa); etc.
                     Also similar to Rv2861c|MAPB PROBABLE METHIONINE
                     AMINOPEPTIDASE from Mycobacterium tuberculosis (285 aa).
                     BELONGS TO PEPTIDASE FAMILY M24A; ALSO KNOWN AS THE MAP
                     FAMILY 1. COFACTOR: COBALT; BINDS 2 IONS PER SUBUNIT.
                     Protein product from Mb0755 detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb0755 found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="GOA:A0A1R3XWC1"
                     /db_xref="InterPro:IPR000994"
                     /db_xref="InterPro:IPR001714"
                     /db_xref="InterPro:IPR002467"
                     /db_xref="InterPro:IPR036005"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XWC1"
BEGIN
        1 MRPLARLRGR RVVPQRSAGE LDAMAAAGAV VAAALRAIRA AAAPGTSSLS LDEIAESVIR
       61 ESGATPSFLG YHGYPASICA SINDRVVHGI PSTAEVLAPG DLVSIDCGAV LDGWHGDAAI
      121 TFGVGALSDA DEALSEATRE SLQAGIAAMV VGNRLTDVAH AIETGTRAAE LRYGRSFGIV
      181 AGYGGHGIGR QMHMDPFLPN EGAPGRGPLL AAGSVLAIEP MLTLGTTKTV VLDDKWTVTT
      241 ADGSRAAHWE HTVAVTDDGP RILTLG
//