LOCUS SIT99354.1 266 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 methionine aminopeptidase mapa (map) (peptidase m) (metap) protein. ACCESSION LT708304-766 PROTEIN_ID SIT99354.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="mapA" /locus_tag="BQ2027_MB0755" /note="Mb0755, mapA, len: 266 aa. Equivalent to Rv0734, len: 266 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 266 aa overlap). Probable mapA, methionine aminopeptidase (map) (EC 3.4.11.18), equivalent to Z98756|MLCB2492_29 probable methionine aminopeptidase from Mycobacterium leprae (266 aa), FASTA scores: opt: 1717, E(): 0, (83.4% identity in 265 aa overlap). Also highly similar to many e.g. T35553 methionine aminopeptidase from Streptomyces coelicolor (278 aa); etc. Also similar to Rv2861c|MAPB PROBABLE METHIONINE AMINOPEPTIDASE from Mycobacterium tuberculosis (285 aa). BELONGS TO PEPTIDASE FAMILY M24A; ALSO KNOWN AS THE MAP FAMILY 1. COFACTOR: COBALT; BINDS 2 IONS PER SUBUNIT. Protein product from Mb0755 detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb0755 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3XWC1" /db_xref="InterPro:IPR000994" /db_xref="InterPro:IPR001714" /db_xref="InterPro:IPR002467" /db_xref="InterPro:IPR036005" /db_xref="UniProtKB/TrEMBL:A0A1R3XWC1" BEGIN 1 MRPLARLRGR RVVPQRSAGE LDAMAAAGAV VAAALRAIRA AAAPGTSSLS LDEIAESVIR 61 ESGATPSFLG YHGYPASICA SINDRVVHGI PSTAEVLAPG DLVSIDCGAV LDGWHGDAAI 121 TFGVGALSDA DEALSEATRE SLQAGIAAMV VGNRLTDVAH AIETGTRAAE LRYGRSFGIV 181 AGYGGHGIGR QMHMDPFLPN EGAPGRGPLL AAGSVLAIEP MLTLGTTKTV VLDDKWTVTT 241 ADGSRAAHWE HTVAVTDDGP RILTLG //