LOCUS       SIT99347.1               218 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE
            L-FUCULOSE PHOSPHATE ALDOLASE FUCA (L-FUCULOSE-1-PHOSPHATE
            ALDOLASE) protein.
ACCESSION   LT708304-759
PROTEIN_ID  SIT99347.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="fucA"
                     /locus_tag="BQ2027_MB0748C"
                     /note="Mb0748c, fucA, len: 218 aa. Equivalent to Rv0727c,
                     len: 218 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.5% identity in 218 aa overlap). Possible fucA,
                     L-fuculose-1-phosphate aldolase (EC 4.1.2.17), similar to
                     many e.g. NP_386339.1|NC_003047 PUTATIVE L-FUCULOSE
                     PHOSPHATE ALDOLASE PROTEIN from Sinorhizobium meliloti
                     (222 aa); P11550|FUCA_ECOLI L-FUCULOSE PHOSPHATE ALDOLASE
                     from Escherichia strain K12 (215 aa), FASTA scores: opt:
                     372, E(): 4.1e-19, (34.6% identity in 185 aa overlap);
                     etc. BELONGS TO THE ALDOLASE CLASS II FAMILY, ARAD/FUCA
                     SUBFAMILY. COFACTOR: BINDS ONE ZINC ION PER MOLECULE.
                     Protein product from Mb0748c detected using SWATH mass
                     spectrometry."
                     /db_xref="InterPro:IPR001303"
                     /db_xref="InterPro:IPR036409"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XWB0"
BEGIN
        1 MNFVDDPESA VLAAAKDMLR RGLVEGTAGN ISARRSDGNV VITPSSVDYA EMLLHDLVLV
       61 DAGGAVLHAK DGRSPSTELN LHLACYRAFD DIGSVIHSHP VWATMFAVAH EPIPACIDEF
      121 AIYCGGDVRC TEYAASGTPE VGRNAVRALE GRAAALIANH GLVAVGPRPD QVLRVTALVE
      181 RTAQIVWGAR ALGGPVPIPE DVCRNFTGVY GYLRANPL
//