LOCUS       SIT99302.1               396 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 probable
            iron-regulated elongation factor tu tuf (ef-tu) protein.
ACCESSION   LT708304-714
PROTEIN_ID  SIT99302.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="tuf"
                     /locus_tag="BQ2027_MB0704"
                     /note="Mb0704, tuf, len: 396 aa. Equivalent to Rv0685,
                     len: 396 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 396 aa overlap). Probable tuf,
                     elongation factor EF-Tu, equivalent to JC2262 translation
                     elongation factor Tu from Mycobacterium leprae (396 aa).
                     Also highly similar to others e.g. P42439|EFTU_CORGL
                     ELONGATION FACTOR TU (EF-TU) from Corynebacterium
                     glutamicum (396 aa); etc. Contains PS00017 ATP/GTP-binding
                     site motif A, and PS00301 GTP-binding elongation factors
                     signature. BELONGS TO THE GTP-BINDING ELONGATION FACTOR
                     FAMILY, EF-TU/EF-1A SUBFAMILY. Protein product from Mb0704
                     detected using shotgun mass spectrometry and SWATH mass
                     spectrometry. Mb0704 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:P0A559"
                     /db_xref="InterPro:IPR000795"
                     /db_xref="InterPro:IPR004160"
                     /db_xref="InterPro:IPR004161"
                     /db_xref="InterPro:IPR004541"
                     /db_xref="InterPro:IPR005225"
                     /db_xref="InterPro:IPR009000"
                     /db_xref="InterPro:IPR009001"
                     /db_xref="InterPro:IPR027417"
                     /db_xref="InterPro:IPR031157"
                     /db_xref="InterPro:IPR033720"
                     /db_xref="InterPro:IPR041709"
                     /db_xref="UniProtKB/Swiss-Prot:P0A559"
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MAKAKFQRTK PHVNIGTIGH VDHGKTTLTA AITKVLHDKF PDLNETKAFD QIDNAPEERQ
       61 RGITINIAHV EYQTDKRHYA HVDAPGHADY IKNMITGAAQ MDGAILVVAA TDGPMPQTRE
      121 HVLLARQVGV PYILVALNKA DAVDDEELLE LVEMEVRELL AAQEFDEDAP VVRVSALKAL
      181 EGDAKWVASV EELMNAVDES IPDPVRETDK PFLMPVEDVF TITGRGTVVT GRVERGVINV
      241 NEEVEIVGIR PSTTKTTVTG VEMFRKLLDQ GQAGDNVGLL LRGVKREDVE RGQVVTKPGT
      301 TTPHTEFEGQ VYILSKDEGG RHTPFFNNYR PQFYFRTTDV TGVVTLPEGT EMVMPGDNTN
      361 ISVKLIQPVA MDEGLRFAIR EGGRTVGAGR VTKIIK
//