LOCUS       SIT99275.1               238 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            CONSERVED INTEGRAL MEMBRANE PROTEIN protein.
ACCESSION   LT708304-687
PROTEIN_ID  SIT99275.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0677C"
                     /note="Mb0677c, -, len: 238 aa. Equivalent to Rv0658c,
                     len: 238 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.6% identity in 238 aa overlap). Probable conserved
                     integral membrane protein, similar to P33774|YPRB_ECOLI
                     hypothetical 24.3 kd protein from Escherichia coli (217
                     aa), FASTA scores: opt: 174, E(): 5.3e-05, (25.6% identity
                     in 223 aa overlap). Also similar to Rv1863c and Rv0804
                     from Mycobacterium tuberculosis. Mb0677c found to be
                     expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="GOA:A0A1R3XWF5"
                     /db_xref="InterPro:IPR003675"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XWF5"
BEGIN
        1 MEAGRADTVA PSHRWGLGAF LVVELVFLVA STSLAVVLTG HGPVSAGVLA LALAAPTVVA
       61 AGLAILITRL RGNGPRTDLR LRWSWRGLRL GLMFGFGGML VTIPASLVYT AIVGPEANSA
      121 VVRIFGGVRA SWPWALVVFL VVVFVAPLCE EIIYRGLLWG AVDRRWGRWA ALVVTTVVFA
      181 LAHLEFARAP LLVVVAIPIA LARFYSGGLL ASIVTHQVTN LLPGIVLLLG LTGAISLP
//