LOCUS       SIT99221.1               133 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 possible
            toxin vapc28. contains pin domain. protein.
ACCESSION   LT708304-633
PROTEIN_ID  SIT99221.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="vapc28"
                     /locus_tag="BQ2027_MB0625"
                     /note="Mb0625, -, len: 133 aa. Equivalent to Rv0609, len:
                     133 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 133 aa overlap). Conserved
                     hypothetical protein, similar to several Mycobacterium
                     tuberculosis hypothetical proteins e.g.
                     YW37_MYCTU|Q10874|Rv1982c|MT2034|MTCY39.37 CONSERVED
                     HYPOTHETICAL PROTEIN (139 aa), FASTA scores: opt: 262,
                     E(): 8.1e-12, (39.1% identity in 128 aa overlap);
                     MTCY20H10.05|Rv0624|MT0652|MTCY20H10.05 CONSERVED
                     HYPOTHETICAL PROTEIN (131 aa), FASTA score: (42.9%
                     identity in 126 aa overlap), Rv0565c, Rv3854c, etc. Mb0625
                     found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing (TPM > 20)."
                     /db_xref="GOA:P67239"
                     /db_xref="InterPro:IPR002716"
                     /db_xref="InterPro:IPR022907"
                     /db_xref="InterPro:IPR029060"
                     /db_xref="UniProtKB/Swiss-Prot:P67239"
BEGIN
        1 MIVDTSAIIA ILRDEDDAAA YADALANADV RRLSAASYLE CGIVLDSQRD PVISRALDEL
       61 IEEAEFVVEP VTERQARLAR AAYADFGRGS GHPAGLNFGD CLSYALAIDR REPLLWKGND
      121 FGHTGVQRAL DRR
//