LOCUS       SIT99217.1               202 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE
            RESOLVASE protein.
ACCESSION   LT708304-629
PROTEIN_ID  SIT99217.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0621"
                     /note="Mb0621, -, len: 202 aa. Equivalent to Rv0605, len:
                     202 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 202 aa overlap). Possible resolvase
                     for IS_Y349 element, similar to several Mycobacterial
                     hypothetical proteins and weakly similar to Q52563
                     resolvase from Pseudomonas syringae (210 aa), FASTA
                     scores: opt: 99, E(): 3.1, (35.7% identity in 98 aa
                     overlap). Contains PS00397 Site-specific recombinases
                     active site and probable helix-turn helix motif from aa
                     9-30 (Score 1815, +5.37 SD). Protein product from Mb0621
                     detected using SWATH mass spectrometry. Mb0621 found to be
                     expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="GOA:A0A1R3XVY1"
                     /db_xref="InterPro:IPR006118"
                     /db_xref="InterPro:IPR006119"
                     /db_xref="InterPro:IPR036162"
                     /db_xref="InterPro:IPR041718"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XVY1"
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MACCRNRGMN LAAWAERNGV ARVTAYRWFH AGLLPVPARK VGRLILVDEL ASEAGAQPKT
       61 AVYARVSSAD QKSDLDRQVA RVTSWATAEQ IPVDKVVTEV GSVLNGHRRK FPAVLRDLSV
      121 TRIVVEHRDR FCRFGSEYVH AALAAQGREL VVVDSAEVDD DLVWDMTEIL TSMCARLYGK
      181 RAAQNRAKRA VAAAAVDDHE AA
//