LOCUS SIT99217.1 202 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE RESOLVASE protein. ACCESSION LT708304-629 PROTEIN_ID SIT99217.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB0621" /note="Mb0621, -, len: 202 aa. Equivalent to Rv0605, len: 202 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 202 aa overlap). Possible resolvase for IS_Y349 element, similar to several Mycobacterial hypothetical proteins and weakly similar to Q52563 resolvase from Pseudomonas syringae (210 aa), FASTA scores: opt: 99, E(): 3.1, (35.7% identity in 98 aa overlap). Contains PS00397 Site-specific recombinases active site and probable helix-turn helix motif from aa 9-30 (Score 1815, +5.37 SD). Protein product from Mb0621 detected using SWATH mass spectrometry. Mb0621 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3XVY1" /db_xref="InterPro:IPR006118" /db_xref="InterPro:IPR006119" /db_xref="InterPro:IPR036162" /db_xref="InterPro:IPR041718" /db_xref="UniProtKB/TrEMBL:A0A1R3XVY1" /experiment="experimental evidence, no additional details recorded" BEGIN 1 MACCRNRGMN LAAWAERNGV ARVTAYRWFH AGLLPVPARK VGRLILVDEL ASEAGAQPKT 61 AVYARVSSAD QKSDLDRQVA RVTSWATAEQ IPVDKVVTEV GSVLNGHRRK FPAVLRDLSV 121 TRIVVEHRDR FCRFGSEYVH AALAAQGREL VVVDSAEVDD DLVWDMTEIL TSMCARLYGK 181 RAAQNRAKRA VAAAAVDDHE AA //