LOCUS SIT98452.1 238 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE MATURASE protein. ACCESSION LT708304-73 PROTEIN_ID SIT98452.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB0072" /note="Mb0072, -, len: 238 aa. Equivalent to Rv0071, len: 235 aa, from Mycobacterium tuberculosis strain H37Rv, (98.7% identity in 238 aa overlap). Possible maturase, similar to many proteins of the group II intron maturase family e.g. P95451|U77945 MATURASE-RELATED PROTEIN from PSEUDOMONAS ALCALIGENES (297 aa), FASTA scores: opt: 395, E(): 1.7e-20, (43.5% identity in 147 aa overlap); N-terminus of AAD16434.1|AF101076 maturase-related protein from Pseudomonas putida (473 aa); N-terminus of NP_437373.1|NC_003078 putative reverse transcriptasematurase protein from Sinorhizobium meliloti (453 aa); etc. Also similar to MLCL581_1 from Mycobacterium leprae. Contains 5 VDP repeats at N-terminus, these are also found in two Streptococcus plasmid hypothetical proteins Q52246|X17092 and Q54942|X66468. REMARK-M.bovis-M.tuberculosis: In Mycobacterium bovis, a 9 bp insertion (*-cggtggacc) leads to a longer product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (238 aa versus 235 aa)." /db_xref="InterPro:IPR000477" /db_xref="UniProtKB/TrEMBL:A0A1R3XU78" BEGIN 1 MSSITVSVDP VDPVDPVDPV DPVDPVDAVV AAGSDGLTVA RIESEIGALE FLNELRTELK 61 SGQFRPQPVR ERKIPKPGGL GKVRRLGIPT VADRVVQAAL KLVLEPIFET DFEPVSYGFR 121 PARRAHDTIA EIHLFGTQEY RWVLDADIKA CFDRIDHADL MDRVRHRIKD KRVLRLVNWQ 181 RIRHRWNWTD VRRWLTDPTG RWHPISADGI TLFNPAAVPI RRYRYRGNTI PTPWTQAV //