LOCUS       SIT98452.1               238 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE
            MATURASE protein.
ACCESSION   LT708304-73
PROTEIN_ID  SIT98452.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0072"
                     /note="Mb0072, -, len: 238 aa. Equivalent to Rv0071, len:
                     235 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (98.7% identity in 238 aa overlap). Possible maturase,
                     similar to many proteins of the group II intron maturase
                     family e.g. P95451|U77945 MATURASE-RELATED PROTEIN from
                     PSEUDOMONAS ALCALIGENES (297 aa), FASTA scores: opt: 395,
                     E(): 1.7e-20, (43.5% identity in 147 aa overlap);
                     N-terminus of AAD16434.1|AF101076 maturase-related protein
                     from Pseudomonas putida (473 aa); N-terminus of
                     NP_437373.1|NC_003078 putative reverse
                     transcriptasematurase protein from Sinorhizobium meliloti
                     (453 aa); etc. Also similar to MLCL581_1 from
                     Mycobacterium leprae. Contains 5 VDP repeats at
                     N-terminus, these are also found in two Streptococcus
                     plasmid hypothetical proteins Q52246|X17092 and
                     Q54942|X66468. REMARK-M.bovis-M.tuberculosis: In
                     Mycobacterium bovis, a 9 bp insertion (*-cggtggacc) leads
                     to a longer product compared to its homolog in
                     Mycobacterium tuberculosis strain H37Rv (238 aa versus 235
                     aa)."
                     /db_xref="InterPro:IPR000477"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XU78"
BEGIN
        1 MSSITVSVDP VDPVDPVDPV DPVDPVDAVV AAGSDGLTVA RIESEIGALE FLNELRTELK
       61 SGQFRPQPVR ERKIPKPGGL GKVRRLGIPT VADRVVQAAL KLVLEPIFET DFEPVSYGFR
      121 PARRAHDTIA EIHLFGTQEY RWVLDADIKA CFDRIDHADL MDRVRHRIKD KRVLRLVNWQ
      181 RIRHRWNWTD VRRWLTDPTG RWHPISADGI TLFNPAAVPI RRYRYRGNTI PTPWTQAV
//