LOCUS       SIT98441.1                79 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Possible
            antitoxin VapB1 protein.
ACCESSION   LT708304-66
PROTEIN_ID  SIT98441.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="vapB1"
                     /locus_tag="BQ2027_MB0065A"
                     /note="Mb0065A, len: 79 aa. Equivalent to Rv0064A len: 79
                     aa, from Mycobacterium tuberculosis strain H37Rv, (98.7%
                     identity in 79 aa overlap). Transferred from H37Rv
                     annotation using Rapid Annotation Transfer Tool (Nucleic
                     Acids Res. 2011 May; 39(9): e57). Possible vapB1,
                     antitoxin, part of toxin-antitoxin (TA) operon with Rv0065
                     (See Arcus et al., 2005; Pandey and Gerdes, 2005). Weakly
                     similar to others in Mycobacterium tuberculosis e.g.
                     Rv0300 (73 aa),Rv1721c (75 aa) Protein product from
                     Mb0065A detected using shotgun mass spectrometry. Mb0065A
                     found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing (TPM > 20)."
                     /db_xref="GOA:A0A1R3XU88"
                     /db_xref="InterPro:IPR010985"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XU88"
BEGIN
        1 MATIQVRDLP EDVAETYRRR ATAAGQSLQT YMRTKLIEGV RGRDKAEVIE ILEQALASTA
       61 SPGISRETIE ASRRELRGG
//