LOCUS SIT98439.1 479 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE OXIDOREDUCTASE protein. ACCESSION LT708304-64 PROTEIN_ID SIT98439.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB0064" /note="Mb0064, -, len: 479 aa. Equivalent to Rv0063, len: 479 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 479 aa overlap). Possible oxidoreductase (EC 1.-.-.-), similar to many e.g. HDNO_ARTOX|P08159 6-hydroxy-d-nicotine oxidase from Arthrobacter oxidans (458 aa), FASTA scores: opt: 343, E(): 3.4e-13, (27.4% identity in 467 aa overlap); AAD28454.1|AF127374_9|AF127374|MitR oxidase from Streptomyces lavendulae (514 aa); AAF81732.1|AF254925|EncM putative FAD-dependent oxygenase from Streptomycesmaritimus (464 aa); etc. Also similar to Mycobacterium tuberculosis proteins e.g. Rv3107c, Rv1257c, etc. Contains PS00862 Oxygen oxidoreductases covalent FAD-binding site. Protein product from Mb0064 detected using SWATH mass spectrometry. Mb0064 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3XU80" /db_xref="InterPro:IPR006093" /db_xref="InterPro:IPR006094" /db_xref="InterPro:IPR006311" /db_xref="InterPro:IPR012951" /db_xref="InterPro:IPR016166" /db_xref="InterPro:IPR016167" /db_xref="InterPro:IPR016169" /db_xref="InterPro:IPR036318" /db_xref="UniProtKB/TrEMBL:A0A1R3XU80" BEGIN 1 MAREISRQTF LRGAAGALAA GAVFGSVRAT ADPAASGWEA LSSALGGKVL QPDDGPQFAT 61 AKQVFNTNYN GYTPAVIVTP TSQLDVQKAM AFAAANNLKV APRGGGHSYV GASTANGAMV 121 LDLRQLPGDI NYDATTGRVT VTPATGLYAM HQVLAAAGRG IPTGTCPTVG VAGHALGGGL 181 GANSRHAGLL CDQLTSASVV LPSGQAVTAS ATDHPDLFWA LRGGGGGNFG VTTSLTFATF 241 PSGDLDVVNL NFPPQSFAQV LVGWQNWLRT ADRGSWALAD ATVDPLGTHC RILATCPAGS 301 GGSVAAAIVS AVGTQPTGTE NHTFNYLDLV RYLAVGNLNP SPLGYVGGSD VFTTITPATA 361 QGIASAVDAF PRGAGRMLAI MHALDGALAT VSPGATAFPW RRQSALVQWY VETSGSPSEA 421 TSWLNTAHQA VRAYSVGGYV NYLEVNQPPA RYFGPNLSRL SAVRQKYDPS RVMFSGLNF //