LOCUS       SIT98439.1               479 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE
            OXIDOREDUCTASE protein.
ACCESSION   LT708304-64
PROTEIN_ID  SIT98439.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0064"
                     /note="Mb0064, -, len: 479 aa. Equivalent to Rv0063, len:
                     479 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 479 aa overlap). Possible
                     oxidoreductase (EC 1.-.-.-), similar to many e.g.
                     HDNO_ARTOX|P08159 6-hydroxy-d-nicotine oxidase from
                     Arthrobacter oxidans (458 aa), FASTA scores: opt: 343,
                     E(): 3.4e-13, (27.4% identity in 467 aa overlap);
                     AAD28454.1|AF127374_9|AF127374|MitR oxidase from
                     Streptomyces lavendulae (514 aa); AAF81732.1|AF254925|EncM
                     putative FAD-dependent oxygenase from
                     Streptomycesmaritimus (464 aa); etc. Also similar to
                     Mycobacterium tuberculosis proteins e.g. Rv3107c, Rv1257c,
                     etc. Contains PS00862 Oxygen oxidoreductases covalent
                     FAD-binding site. Protein product from Mb0064 detected
                     using SWATH mass spectrometry. Mb0064 found to be
                     expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="GOA:A0A1R3XU80"
                     /db_xref="InterPro:IPR006093"
                     /db_xref="InterPro:IPR006094"
                     /db_xref="InterPro:IPR006311"
                     /db_xref="InterPro:IPR012951"
                     /db_xref="InterPro:IPR016166"
                     /db_xref="InterPro:IPR016167"
                     /db_xref="InterPro:IPR016169"
                     /db_xref="InterPro:IPR036318"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XU80"
BEGIN
        1 MAREISRQTF LRGAAGALAA GAVFGSVRAT ADPAASGWEA LSSALGGKVL QPDDGPQFAT
       61 AKQVFNTNYN GYTPAVIVTP TSQLDVQKAM AFAAANNLKV APRGGGHSYV GASTANGAMV
      121 LDLRQLPGDI NYDATTGRVT VTPATGLYAM HQVLAAAGRG IPTGTCPTVG VAGHALGGGL
      181 GANSRHAGLL CDQLTSASVV LPSGQAVTAS ATDHPDLFWA LRGGGGGNFG VTTSLTFATF
      241 PSGDLDVVNL NFPPQSFAQV LVGWQNWLRT ADRGSWALAD ATVDPLGTHC RILATCPAGS
      301 GGSVAAAIVS AVGTQPTGTE NHTFNYLDLV RYLAVGNLNP SPLGYVGGSD VFTTITPATA
      361 QGIASAVDAF PRGAGRMLAI MHALDGALAT VSPGATAFPW RRQSALVQWY VETSGSPSEA
      421 TSWLNTAHQA VRAYSVGGYV NYLEVNQPPA RYFGPNLSRL SAVRQKYDPS RVMFSGLNF
//