LOCUS SIT98406.1 298 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE HYDROLASE protein. ACCESSION LT708304-46 PROTEIN_ID SIT98406.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB0046C" /note="Mb0046c, -, len: 298 aa. Equivalent to Rv0045c, len 298 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 298 aa overlap). Possible hydrolase (EC 3.-.-.-), showing similarity with others eg NP_107230.1|NC_002678 putative hydrolase from Mesorhizobium loti (278 aa); CAB56730.1|AL121600 putative hydrolase from Streptomyces coelicolor (302 aa); NP_438361.1|NC_000907 putative esterase/lipase from Haemophilus influenzae Rd (287 aa); etc. Also similar to Mycobacterium tuberculosis proteins Rv3473c, Rv1123c, Rv1938, Rv3617, Rv3670, etc. Protein product from Mb0046c detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb0046c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3XU63" /db_xref="InterPro:IPR000073" /db_xref="InterPro:IPR029058" /db_xref="UniProtKB/TrEMBL:A0A1R3XU63" BEGIN 1 MLSDDELTGL DEFALLAENA EQAGVNGPLP EVERVQAGAI SALRWGGSAP RVIFLHGGGQ 61 NAHTWDTVIV GLGEPALAVD LPGHGHSAWR EDGNYSPQLN SETLAPVLRE LAPGAEFVVG 121 MSLGGLTAIR LAAMAPDLVG ELVLVDVTPS ALQRHAELTA EQRGTVALMH GEREFPSFQA 181 MLDLTIAAAP HRDVKSLRRG VFHNSRRLDN GNWVWRYDAI RTFGDFAGLW DDVDALSAPI 241 TLVRGGSSGF VTDQDTAELH RRATHFRGVH IVEKSGHSVQ SDQPRALIEI VRGVLDTR //