LOCUS       SIT98404.1               244 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY GNTR-FAMILY)
            protein.
ACCESSION   LT708304-44
PROTEIN_ID  SIT98404.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0044C"
                     /note="Mb0044c, -, len: 244 aa. Equivalent to Rv0043c,
                     len: 244 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 244 aa overlap). Probable
                     transcriptional regulator, GntR family, similar to others
                     e.g. NP_420584.1|NC_002696 transcriptional regulator GntR
                     family from Caulobacter crescentus (221 aa);
                     NP_294539.1|NC_001263 transcriptional regulator GntR
                     family from Deinococcus radiodurans (267 aa);
                     YIN1_STRAM|P32425 hypothetical transcriptional regulatory
                     protein from Streptomyces ambofaciens (236 aa), FASTA
                     scores: opt: 170, E(): 9.8e-05, (27.6% identity in 127 aa
                     overlap); etc. Similar also to SC9B10_7 from Streptomyces
                     coelicolor FASTA score: E():0.00038; and Rv0165c|MTCI28_5
                     from Mycobacterium tuberculosis (264 aa), FASTA score:
                     (27.7% identity in 130 aa overlap). Mb0044c found to be
                     expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="GOA:P67738"
                     /db_xref="InterPro:IPR000524"
                     /db_xref="InterPro:IPR008920"
                     /db_xref="InterPro:IPR036388"
                     /db_xref="InterPro:IPR036390"
                     /db_xref="UniProtKB/Swiss-Prot:P67738"
BEGIN
        1 MPKKYGVKEK DQVVAHILNL LLTGKLRSGD RVDRNEIAHG LGVSRVPIQE ALVQLEHDGI
       61 VSTRYHRGAF IERFDVATIL EHHELDGLLN GIASARAAAN PTPRILGQLD AVMRSLRNSK
      121 ESRAFAECVW EYRRTVNDEY AGPRLHATIR ASQNLIPRVF WMTYQNSRDD VLPFYEEENA
      181 AIHRREPEAA RAACIGRSEL MAQTMLAELF RRRVLVPPEG ACPGPFGAPI PGFARSYQPS
      241 SPVP
//