LOCUS SIT98404.1 244 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY GNTR-FAMILY) protein. ACCESSION LT708304-44 PROTEIN_ID SIT98404.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB0044C" /note="Mb0044c, -, len: 244 aa. Equivalent to Rv0043c, len: 244 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 244 aa overlap). Probable transcriptional regulator, GntR family, similar to others e.g. NP_420584.1|NC_002696 transcriptional regulator GntR family from Caulobacter crescentus (221 aa); NP_294539.1|NC_001263 transcriptional regulator GntR family from Deinococcus radiodurans (267 aa); YIN1_STRAM|P32425 hypothetical transcriptional regulatory protein from Streptomyces ambofaciens (236 aa), FASTA scores: opt: 170, E(): 9.8e-05, (27.6% identity in 127 aa overlap); etc. Similar also to SC9B10_7 from Streptomyces coelicolor FASTA score: E():0.00038; and Rv0165c|MTCI28_5 from Mycobacterium tuberculosis (264 aa), FASTA score: (27.7% identity in 130 aa overlap). Mb0044c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:P67738" /db_xref="InterPro:IPR000524" /db_xref="InterPro:IPR008920" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="UniProtKB/Swiss-Prot:P67738" BEGIN 1 MPKKYGVKEK DQVVAHILNL LLTGKLRSGD RVDRNEIAHG LGVSRVPIQE ALVQLEHDGI 61 VSTRYHRGAF IERFDVATIL EHHELDGLLN GIASARAAAN PTPRILGQLD AVMRSLRNSK 121 ESRAFAECVW EYRRTVNDEY AGPRLHATIR ASQNLIPRVF WMTYQNSRDD VLPFYEEENA 181 AIHRREPEAA RAACIGRSEL MAQTMLAELF RRRVLVPPEG ACPGPFGAPI PGFARSYQPS 241 SPVP //