LOCUS       SIT98403.1               208 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE
            TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY MARR-FAMILY)
            protein.
ACCESSION   LT708304-43
PROTEIN_ID  SIT98403.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0043C"
                     /note="Mb0043c, -, len: 208 aa. Equivalent to Rv0042c,
                     len: 208 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 208 aa overlap). Possible
                     transcriptional regulatory protein, MarR-family, highly
                     similar except in N-terminus to CAC32228.1|AL583926
                     putative MarR-family regulatory protein from Mycobacterium
                     leprae (243 aa). Also similar in part to others e.g.
                     AB76343.1|AL158061 putative MarR-family transcriptional
                     regulator from Streptomyces coelicolor (163 aa);
                     NP_384406.1|NC_003047 PUTATIVE TRANSCRIPTION REGULATOR
                     PROTEIN from Sinorhizobium meliloti (164 aa);
                     NP_531782.1|NC_003304 transcriptional regulator, MarR
                     family from Agrobacterium tumefaciens (151 aa); etc. Also
                     some similarity to Mycobacterium tuberculosis proteins
                     Rv2327, Rv0880, and Rv1404. Protein product from Mb0043c
                     detected using shotgun mass spectrometry. Mb0043c found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing (TPM > 20)."
                     /db_xref="GOA:A0A1R3XU39"
                     /db_xref="InterPro:IPR000835"
                     /db_xref="InterPro:IPR036388"
                     /db_xref="InterPro:IPR036390"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XU39"
BEGIN
        1 MSVVRSIGKK MQRISGPNAL AVKGRPTQVY GHTHVRLDCR FMADSEFTAP EVTQLAEGLH
       61 RALSKLISML RRGDPNGAAA GDLTLAQLSI LVTLLDQGPI RMTDLAAHER VRTPTTTVAI
      121 RRLEKIGLVK RSRDPSDLRA VLVDITPQGR AVHGESLANR RAALAALLSQ LPRSDLETLR
      181 KALAPLERLA SGEPASGPAS NSPARKRA
//