LOCUS SIT98366.1 322 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 putative oxidoreductase, nitronate monooxygenase family protein. ACCESSION LT708304-21 PROTEIN_ID SIT98366.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB0021C" /note="Mb0021c, -, len: 322 aa. Equivalent to Rv0021c, len: 322 aa, from Mycobacterium tuberculosis strain H37Rv, (99.7% identity in 322 aa overlap). Conserved hypothetical protein, similar to various proteins e.g. NP_464341.1|NC_003210 protein similar to oxidoreductases from Listeria monocytogenes (309 aa); NP_357973.1|NC_003098 Enoyl-acyl carrier protein(ACP) reductase from Streptococcus pneumoniae (324 aa); 2NPD_NEUCR|G726338 2-nitropropane dioxygenase precursor from Neurospora crassa (378 aa), FASTA scores: opt: 383, E(): 1.1e-16, (32.2% identity in 348 aa overlap); etc. Also similar to AE001747_25 from Thermotoga maritima section 59 (314 aa), FASTA scores: opt: 442, E(): 1.5e-19, (30.5% identity in 325 aa overlap). Also similar to other proteins from Mycobacterium tuberculosis e.g. Rv3553 (355 aa), FASTA scores: E(): 6.8e-15, (35.3 identity in 235 aa overlap); and Rv1533 (375 aa), FASTA scores: E(): 4.7e-12, (34.4% identity in 262 aa overlap). Mb0021c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3XU19" /db_xref="InterPro:IPR004136" /db_xref="InterPro:IPR013785" /db_xref="UniProtKB/TrEMBL:A0A1R3XU19" BEGIN 1 MVLSTAFSQM FGIDYPIVSA PMDLIAGGEL AAAVSGAGGL GLIGGGYGDR DWLARQFDLA 61 AGAPVGCGFI TWSLARQPQL LDLALQYEPV AVMLSFGDPA VFADAIKSAG TRLVCQIQNR 121 TQAERALQVG ADVLVAQGTE AGGHGHGPRS TLTLVPEIVD LVTARGTDIP VIAAGGIADG 181 RGLAAALMLG AAGVLVGTRF YATVEALSTP QARDPLLAAT GDDMCRTTIY DQLRRYPWPQ 241 GHTMSVLSNA LTDQFEDTEL DILHREEAMA RYWRAVPARD YSIANVTAGQ AAGLVNAVLP 301 AADVITGMAQ QAARTLTAMR AV //