LOCUS       SIT98366.1               322 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 putative
            oxidoreductase, nitronate monooxygenase family protein.
ACCESSION   LT708304-21
PROTEIN_ID  SIT98366.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0021C"
                     /note="Mb0021c, -, len: 322 aa. Equivalent to Rv0021c,
                     len: 322 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.7% identity in 322 aa overlap). Conserved hypothetical
                     protein, similar to various proteins e.g.
                     NP_464341.1|NC_003210 protein similar to oxidoreductases
                     from Listeria monocytogenes (309 aa);
                     NP_357973.1|NC_003098 Enoyl-acyl carrier protein(ACP)
                     reductase from Streptococcus pneumoniae (324 aa);
                     2NPD_NEUCR|G726338 2-nitropropane dioxygenase precursor
                     from Neurospora crassa (378 aa), FASTA scores: opt: 383,
                     E(): 1.1e-16, (32.2% identity in 348 aa overlap); etc.
                     Also similar to AE001747_25 from Thermotoga maritima
                     section 59 (314 aa), FASTA scores: opt: 442, E(): 1.5e-19,
                     (30.5% identity in 325 aa overlap). Also similar to other
                     proteins from Mycobacterium tuberculosis e.g. Rv3553 (355
                     aa), FASTA scores: E(): 6.8e-15, (35.3 identity in 235 aa
                     overlap); and Rv1533 (375 aa), FASTA scores: E(): 4.7e-12,
                     (34.4% identity in 262 aa overlap). Mb0021c found to be
                     expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="GOA:A0A1R3XU19"
                     /db_xref="InterPro:IPR004136"
                     /db_xref="InterPro:IPR013785"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XU19"
BEGIN
        1 MVLSTAFSQM FGIDYPIVSA PMDLIAGGEL AAAVSGAGGL GLIGGGYGDR DWLARQFDLA
       61 AGAPVGCGFI TWSLARQPQL LDLALQYEPV AVMLSFGDPA VFADAIKSAG TRLVCQIQNR
      121 TQAERALQVG ADVLVAQGTE AGGHGHGPRS TLTLVPEIVD LVTARGTDIP VIAAGGIADG
      181 RGLAAALMLG AAGVLVGTRF YATVEALSTP QARDPLLAAT GDDMCRTTIY DQLRRYPWPQ
      241 GHTMSVLSNA LTDQFEDTEL DILHREEAMA RYWRAVPARD YSIANVTAGQ AAGLVNAVLP
      301 AADVITGMAQ QAARTLTAMR AV
//