LOCUS       SIT98363.1               514 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 phosphoserine/
            threonine phosphatase pstp protein.
ACCESSION   LT708304-18
PROTEIN_ID  SIT98363.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="pstp"
                     /locus_tag="BQ2027_MB0018C"
                     /note="Mb0018c, ppp, len: 514 aa. Equivalent to Rv0018c,
                     len: 514 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.4% identity in 514 aa overlap). Possible ppp,
                     serine/threonine phosphatase (EC 3.1.3.16), equivalent to
                     MLCB1770_13|T10013 PUTATIVE PHOSPHOPROTEIN PHOSPHATASE
                     from Mycobacterium leprae (509 aa), FASTA scores: opt:
                     2517, E(): 0. Also highly similar to others e.g. T36714
                     probable protein phosphatase from Streptomyces coelicolor
                     (515 aa); CAA10712.1|AJ132604 pppL protein from
                     Lactococcus lactis (258 aa); NP_248765.1|NC_002516
                     probable phosphoprotein phosphatase from Pseudomonas
                     aeruginosa (242 aa); etc. Also similar to BSUB0009_46 YLOO
                     PROTEIN from Bacillus subtilis (254 aa), FASTA score:
                     (34.0% identity in 250 aa overlap). Protein product from
                     Mb0018c detected using shotgun mass spectrometry and SWATH
                     mass spectrometry. Mb0018c found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:A0A1R3XV75"
                     /db_xref="InterPro:IPR001932"
                     /db_xref="InterPro:IPR015655"
                     /db_xref="InterPro:IPR036457"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XV75"
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MALVTLVLRY AARSDRGLVR ANNEDSVYAG ARLLALADGM GGHAAGEVAS QLVIAALAHL
       61 DDDEPGGDLL AKLDAAVRAG NSAIAAQVEM EPDLEGMGTT LTAILFAGNR LGLVHIGDSR
      121 GYLLRDGELT QITKDDTFVQ TLVDEGRITP EEAHSHPQRS LIMRALTGHE VEPTLTMREA
      181 RAGDRYLLCS DGLSDPVSDE TILEALQIPE VAESAHRLIE LALRGGGPDN VTVVVADVVD
      241 YDYGQTQPIL AGAVSGDDDQ LTLPNTAAGR ASAISQRKEI VKRVPPQADT FSRPRWSGRR
      301 LAFVVALVTV LMTAGLLIGR AIIRSNYYVA DYAGSVSIMR GIQGSLLGMS LHQPYLMGCL
      361 SPRNELSQIS YGQSGGPLDC HLMKLEDLRP PERAQVRAGL PAGTLDDAIG QLRELAANSL
      421 LPPCPAPRAT SPPGRPAPPT TSETTEPNVT SSPAAPSPTT SASAPTGTTP AIPTSASPAA
      481 PASPPTPWPV TSSPTMAALP PPPPQPGIDC RAAA
//