LOCUS       SIT98362.1               469 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            CELL DIVISION PROTEIN RODA protein.
ACCESSION   LT708304-17
PROTEIN_ID  SIT98362.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="rodA"
                     /locus_tag="BQ2027_MB0017C"
                     /note="Mb0017c, rodA, len: 469 aa. Equivalent to Rv0017c,
                     len: 469 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 469 aa overlap). Probable rodA
                     (alternate gene name: ftsW), cell division protein,
                     integral membrane protein, equivalent to
                     MLCB1770_12|T10012 probable cell division protein from
                     Mycobacterium leprae (465 aa), FASTA scores: opt: 2475,
                     E(): 0, (81.9% identity in 469 aa overlap). Also highly
                     similar to others e.g. T36715|SCH69.16 from Streptomyces
                     coelicolor (479 aa); NP_243432.1|NC_002570 from Bacillus
                     halodurans (366 aa); NP_347145.1|NC_003030 from
                     Clostridium acetobutylicum (400 aa); etc. Also similar to
                     MTCY270_14 from Mycobacterium tuberculosis FASTA score:
                     (32.2% identity in 369 aa overlap). BELONGS TO THE
                     FTSW/RODA/SPOVE FAMILY. Protein product from Mb0017c
                     detected using SWATH mass spectrometry. Mb0017c found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="GOA:P63761"
                     /db_xref="InterPro:IPR001182"
                     /db_xref="InterPro:IPR018365"
                     /db_xref="UniProtKB/Swiss-Prot:P63761"
BEGIN
        1 MTTRLQAPVA VTPPLPTRRN AELLLLCFAA VITFAALLVV QANQDQGVPW DLTSYGLAFL
       61 TLFGSAHLAI RRFAPYTDPL LLPVVALLNG LGLVMIHRLD LVDNEIGEHR HPSANQQMLW
      121 TLVGVAAFAL VVTFLKDHRQ LARYGYICGL AGLVFLAVPA LLPAALSEQN GAKIWIRLPG
      181 FSIQPAEFSK ILLLIFFSAV LVAKRGLFTS AGKHLLGMTL PRPRDLAPLL AAWVISVGVM
      241 VFEKDLGASL LLYTSFLVVV YLATQRFSWV VIGLTLFAAG TLVAYFIFEH VRLRVQTWLD
      301 PFADPDGTGY QIVQSLFSFA TGGIFGTGLG NGQPDTVPAA STDFIIAAFG EELGLVGLTA
      361 ILMLYTIVII RGLRTAIATR DSFGKLLAAG LSSTLAIQLF IVVGGVTRLI PLTGLTTPWM
      421 SYGGSSLLAN YILLAILARI SHGARRPLRT RPRNKSPITA AGTEVIERV
//