LOCUS SIT98362.1 469 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE CELL DIVISION PROTEIN RODA protein. ACCESSION LT708304-17 PROTEIN_ID SIT98362.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="rodA" /locus_tag="BQ2027_MB0017C" /note="Mb0017c, rodA, len: 469 aa. Equivalent to Rv0017c, len: 469 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 469 aa overlap). Probable rodA (alternate gene name: ftsW), cell division protein, integral membrane protein, equivalent to MLCB1770_12|T10012 probable cell division protein from Mycobacterium leprae (465 aa), FASTA scores: opt: 2475, E(): 0, (81.9% identity in 469 aa overlap). Also highly similar to others e.g. T36715|SCH69.16 from Streptomyces coelicolor (479 aa); NP_243432.1|NC_002570 from Bacillus halodurans (366 aa); NP_347145.1|NC_003030 from Clostridium acetobutylicum (400 aa); etc. Also similar to MTCY270_14 from Mycobacterium tuberculosis FASTA score: (32.2% identity in 369 aa overlap). BELONGS TO THE FTSW/RODA/SPOVE FAMILY. Protein product from Mb0017c detected using SWATH mass spectrometry. Mb0017c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:P63761" /db_xref="InterPro:IPR001182" /db_xref="InterPro:IPR018365" /db_xref="UniProtKB/Swiss-Prot:P63761" BEGIN 1 MTTRLQAPVA VTPPLPTRRN AELLLLCFAA VITFAALLVV QANQDQGVPW DLTSYGLAFL 61 TLFGSAHLAI RRFAPYTDPL LLPVVALLNG LGLVMIHRLD LVDNEIGEHR HPSANQQMLW 121 TLVGVAAFAL VVTFLKDHRQ LARYGYICGL AGLVFLAVPA LLPAALSEQN GAKIWIRLPG 181 FSIQPAEFSK ILLLIFFSAV LVAKRGLFTS AGKHLLGMTL PRPRDLAPLL AAWVISVGVM 241 VFEKDLGASL LLYTSFLVVV YLATQRFSWV VIGLTLFAAG TLVAYFIFEH VRLRVQTWLD 301 PFADPDGTGY QIVQSLFSFA TGGIFGTGLG NGQPDTVPAA STDFIIAAFG EELGLVGLTA 361 ILMLYTIVII RGLRTAIATR DSFGKLLAAG LSSTLAIQLF IVVGGVTRLI PLTGLTTPWM 421 SYGGSSLLAN YILLAILARI SHGARRPLRT RPRNKSPITA AGTEVIERV //