LOCUS       SIT98354.1               111 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            CONSERVED MEMBRANE PROTEIN protein.
ACCESSION   LT708304-10
PROTEIN_ID  SIT98354.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0010C"
                     /note="Mb0010c, -, len: 111 aa. Equivalent to Rv0010c,
                     len: 141 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 110 aa overlap). Probable conserved
                     membrane protein, equivalent to NP_301139.1|NC_002677
                     putative membrane protein from Mycobacterium leprae (137
                     aa); and similar to Rv1417|P71686|YE17_MYCTU HYPOTHETICAL
                     16.4 KD PROTEIN from Mycobacterium tuberculosis (154 aa),
                     FASTA scores: opt: 121, E(): 0.097, (29.6% identity in 81
                     aa overlap). REMARK-M.bovis-M.tuberculosis: In
                     Mycobacterium bovis, a single base deletion (g-*) leads to
                     a shorter product compared to its homolog in Mycobacterium
                     tuberculosis strain H37Rv (111 aa versus 141 aa). Mb0010c
                     found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing (TPM > 20)."
                     /db_xref="GOA:A0A1R3XUN1"
                     /db_xref="InterPro:IPR019692"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XUN1"
BEGIN
        1 MQQTAWAPRT SGIAGCGAGG VVMAIASVTL VTDTPGRVLT GVAALGLILF ASATWRARPR
       61 LAITPDGLAI RGWFRTQLLR HSNIKIIRID EFRRYGRLVR LLEIETVSGG C
//