LOCUS SIT98347.1 304 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE CONSERVED MEMBRANE PROTEIN protein. ACCESSION LT708304-7 PROTEIN_ID SIT98347.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB0007" /note="Mb0007, -, len: 304 aa. Equivalent to Rv0007, len: 304 aa, from Mycobacterium tuberculosis strain H37Rv, (99.7% identity in 304 aa overlap). Possible conserved membrane protein, highly similar to Z70722|MLCB1770_7 from Mycobacterium leprae (303 aa), FASTA scores: opt: 812, E(): 1.6e-25, (54.2% identity in 319 aa overlap). C-terminal part highly similar to C-terminus of CAB92992.1|AL357152 putative integral membrane protein from Streptomyces coelicolor (185 aa); and N-terminal part highly similar to C-terminus of NP_302684.1|NC_002677 hypothetical protein from Mycobacterium leprae (123 aa). Protein product from Mb0007 detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb0007 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing (TPM > 20)." /db_xref="GOA:A0A1R3XW78" /db_xref="InterPro:IPR021949" /db_xref="UniProtKB/TrEMBL:A0A1R3XW78" /experiment="experimental evidence, no additional details recorded" BEGIN 1 MTAPNEPGAL SKGDGPNADG LVDRGGAHRA ATGPGRIPDA GDPPPWQRAA TRQSQAGHRQ 61 PPPVSHPEGR PTNPPAAADA RLNRFISGAS APVTGPAAAV RTPQPDPDAS LGCGDGSPAE 121 AYASELPDLS GPTPRAPQRN PAPARPAEGG AGSRGDSAAG SSGGRSITAE SRDARVQLSA 181 RRSRGPVRAS MQIRRIDPWS TLKVSLLLSV ALFFVWMITV AFLYLVLGGM GVWAKLNSNV 241 GDLLNNASGS SAELVSSGTI FGGAFLIGLV NVVLMTALAT IGAFVYNLIT DLIGGIEVTL 301 ADRD //