LOCUS       SIT98347.1               304 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE
            CONSERVED MEMBRANE PROTEIN protein.
ACCESSION   LT708304-7
PROTEIN_ID  SIT98347.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0007"
                     /note="Mb0007, -, len: 304 aa. Equivalent to Rv0007, len:
                     304 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.7% identity in 304 aa overlap). Possible conserved
                     membrane protein, highly similar to Z70722|MLCB1770_7 from
                     Mycobacterium leprae (303 aa), FASTA scores: opt: 812,
                     E(): 1.6e-25, (54.2% identity in 319 aa overlap).
                     C-terminal part highly similar to C-terminus of
                     CAB92992.1|AL357152 putative integral membrane protein
                     from Streptomyces coelicolor (185 aa); and N-terminal part
                     highly similar to C-terminus of NP_302684.1|NC_002677
                     hypothetical protein from Mycobacterium leprae (123 aa).
                     Protein product from Mb0007 detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb0007 found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing (TPM > 20)."
                     /db_xref="GOA:A0A1R3XW78"
                     /db_xref="InterPro:IPR021949"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XW78"
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MTAPNEPGAL SKGDGPNADG LVDRGGAHRA ATGPGRIPDA GDPPPWQRAA TRQSQAGHRQ
       61 PPPVSHPEGR PTNPPAAADA RLNRFISGAS APVTGPAAAV RTPQPDPDAS LGCGDGSPAE
      121 AYASELPDLS GPTPRAPQRN PAPARPAEGG AGSRGDSAAG SSGGRSITAE SRDARVQLSA
      181 RRSRGPVRAS MQIRRIDPWS TLKVSLLLSV ALFFVWMITV AFLYLVLGGM GVWAKLNSNV
      241 GDLLNNASGS SAELVSSGTI FGGAFLIGLV NVVLMTALAT IGAFVYNLIT DLIGGIEVTL
      301 ADRD
//