LOCUS SIT98341.1 187 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Zn- ribbon-containing, possibly RNA-binding protein and truncated derivatives protein. ACCESSION LT708304-4 PROTEIN_ID SIT98341.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB0004" /note="Mb0004, -, len: 187 aa. Equivalent to Rv0004, len: 187 aa, from Mycobacterium tuberculosis strain H37Rv, (99.5% identity in 187 aa overlap). Conserved hypothetical protein (see citation below), highly similar, but longer 21 aa in N-terminus, to AAF33696.1|AF222789 unknown protein from Mycobacterium avium subsp. paratuberculosis (166 aa); and highly similar to NP_301132.1|NC_002677 conserved hypothetical protein from Mycobacterium leprae (189 aa); S70990 hypothetical protein from Mycobacterium smegmatis (194 aa). Also similar to in C-terminus to C-terminal part of P35925|YREG_STRCO HYPOTHETICAL 19.8 KDA PROTEIN (IN RECF-GYRB INTERGENIC REGION) from Streptomyces coelicolor (190 aa), FASTA scores: opt: 404, E(): 3.9e-18, (40.7% identity in 189 aa overlap). Mb0004 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="InterPro:IPR007922" /db_xref="InterPro:IPR023007" /db_xref="UniProtKB/Swiss-Prot:Q7U313" BEGIN 1 MTGSVDRPDQ NRGERLMKSP GLDLVRRTLD EARAAARARG QDAGRGRVAS VASGRVAGRR 61 RSWSGPGPDI RDPQPLGKAA RELAKKRGWS VRVAEGMVLG QWSAVVGHQI AEHARPTALN 121 DGVLSVIAES TAWATQLRIM QAQLLAKIAA AVGNDVVRSL KITGPAAPSW RKGPRHIAGR 181 GPRDTYG //