LOCUS       SIT98341.1               187 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Zn-
            ribbon-containing, possibly RNA-binding protein and truncated
            derivatives protein.
ACCESSION   LT708304-4
PROTEIN_ID  SIT98341.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0004"
                     /note="Mb0004, -, len: 187 aa. Equivalent to Rv0004, len:
                     187 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.5% identity in 187 aa overlap). Conserved hypothetical
                     protein (see citation below), highly similar, but longer
                     21 aa in N-terminus, to AAF33696.1|AF222789 unknown
                     protein from Mycobacterium avium subsp. paratuberculosis
                     (166 aa); and highly similar to NP_301132.1|NC_002677
                     conserved hypothetical protein from Mycobacterium leprae
                     (189 aa); S70990 hypothetical protein from Mycobacterium
                     smegmatis (194 aa). Also similar to in C-terminus to
                     C-terminal part of P35925|YREG_STRCO HYPOTHETICAL 19.8 KDA
                     PROTEIN (IN RECF-GYRB INTERGENIC REGION) from Streptomyces
                     coelicolor (190 aa), FASTA scores: opt: 404, E(): 3.9e-18,
                     (40.7% identity in 189 aa overlap). Mb0004 found to be
                     expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="InterPro:IPR007922"
                     /db_xref="InterPro:IPR023007"
                     /db_xref="UniProtKB/Swiss-Prot:Q7U313"
BEGIN
        1 MTGSVDRPDQ NRGERLMKSP GLDLVRRTLD EARAAARARG QDAGRGRVAS VASGRVAGRR
       61 RSWSGPGPDI RDPQPLGKAA RELAKKRGWS VRVAEGMVLG QWSAVVGHQI AEHARPTALN
      121 DGVLSVIAES TAWATQLRIM QAQLLAKIAA AVGNDVVRSL KITGPAAPSW RKGPRHIAGR
      181 GPRDTYG
//