LOCUS SBV53400.1 494 aa PRT CON 06-FEB-2024 DEFINITION Caenorhabditis elegans Inward rectifier potassium channel irk-1 protein. ACCESSION BX284606-146 PROTEIN_ID SBV53400.1 SOURCE Caenorhabditis elegans ORGANISM Caenorhabditis elegans Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis. REFERENCE 1 (bases 1 to 17718942) AUTHORS WormBase. CONSRTM WormBase Consortium JOURNAL Submitted (04-FEB-2024) to the INSDC. WormBase Group, European Bioinformatics Institute, Cambridge, CB10 1SA, UK. Email: help@wormbase.org REFERENCE 2 (bases 1 to 17718942) AUTHORS Sulson J.E., Waterston R. JOURNAL Submitted (03-MAR-2003) to the INSDC. Nematode Sequencing Project: Sanger Institute, Hinxton, Cambridge CB10 1SA, UK and The Genome Institute at Washington University, St. Louis, MO 63110, USA. REFERENCE 3 (bases 1 to 17718942) AUTHORS Sulson J.E., Waterston R. CONSRTM Caenorhabditis elegans Sequencing Consortium TITLE Genome sequence of the nematode C. elegans: a platform for investigating biology JOURNAL Science 282(5396), 2012-2018(1998). COMMENT Annotated features correspond to WormBase release WS292. Protein-coding gene structures below are the result of integration and manual review of the following types of data: ab initio predictions by Genefinder (P. Green and L. Hillier, pers. comm.); alignments to published proteins and cDNAs; genome sequence conservation with other nematodes (e.g. to C. briggsae using WABA: Genome Res. 2000. 10:1115-1125); sequence features (such as trans-splice and polyA sites). Sources of data: large-scale EST projects of Yuji Kohara (http://www.ddbj.nig.ac.jp/c-elegans/html/CE_INDEX.html); ORFeome cloning project (http://worfdb.dfci.harvard.edu); RST large-scale sequencing project (Genome Res. 2009. 19:2334-2342); IST library (Science. 2004. 303:540-3); RT-PCR EST set (Ewing B. Green P. 2010 Unpublished); UTRome EST data submission (UTRome v1 Mangone M. Piano F. 2009); TEC-RED data (PNAS 2004. 101:1650-1655); RNA Deep sequencing data (454 read clusters - Makedonka Mitreva, unpublished; Illumina sequence data, Genome Res. 2009. 19:657-66); Numerous data sets from the modENCODE project (Science. 2010. 330:1775-87); Individual C. elegans Nucleotide Database submissions; Personal communications with C. elegans researchers; Non-Coding gene structures below are derived using the following methods and data: ab initio prediction of tRNAs by tRNAscan-SE (Nucl. Acids. Res., 25, 955-964); integration and appraisal of miRNAs from miRBase (http://www.mirbase.org); integration and appraisal of RFAM predictions (rfam.sanger.ac.uk); 21U-RNAs (Cell. 2006. 127:1193-1207); modENCODE data (Science. 2010. 330:1775-87); manual curation of novel published ncRNAs from the literature. FEATURES Qualifiers source /organism="Caenorhabditis elegans" /chromosome="X" /strain="Bristol N2" /mol_type="genomic DNA" /db_xref="taxon:6239" protein /transl_table=1 /gene="irk-2" /locus_tag="CELE_M02A10.2" /standard_name="M02A10.2f" /note="Confirmed by transcript evidence" /db_xref="GOA:A0A1C3NSR3" /db_xref="InterPro:IPR013518" /db_xref="InterPro:IPR014756" /db_xref="InterPro:IPR016449" /db_xref="InterPro:IPR040445" /db_xref="InterPro:IPR041647" /db_xref="UniProtKB/TrEMBL:A0A1C3NSR3" /db_xref="WormBase:WBGene00002150" intron_pos 31:1 (1/15) intron_pos 70:0 (2/15) intron_pos 88:2 (3/15) intron_pos 134:0 (4/15) intron_pos 168:2 (5/15) intron_pos 193:0 (6/15) intron_pos 220:0 (7/15) intron_pos 251:0 (8/15) intron_pos 273:2 (9/15) intron_pos 316:1 (10/15) intron_pos 345:2 (11/15) intron_pos 387:0 (12/15) intron_pos 426:0 (13/15) intron_pos 447:0 (14/15) intron_pos 484:1 (15/15) BEGIN 1 MPQNFVERVE RLALANGRLP GRSLLLDREQ AQRMLDIEEP LVKNKKYPFF KTPRLGGSRR 61 IRNRLVQKQG LCNISLKNVP KQRRKYFSDI FTTVIEMKWR WCLLYFSLSF MISWSFFATV 121 YFLIAKQHGD IEQIANATWT PCIVNVHNEL NAFLFSFTTQ TTIGYGFRYP TDACPLTIVT 181 MCFQFMWGVM TQTLMAGIIF SKLARPIKRA ATLIFSKNAV ICLRDGKLCL LFRVGDMRKS 241 SLAEAHVRLQ MIKRCVTYEG ELLPFHQFDM DVGYDQGLDR VFVIWPITIC HEIDERSPLW 301 EIGADDLKSA KFEIIAILEG VVESVGSTTQ ARTSYLPSEI LWGHRFEKLV HYKKENGQYN 361 IDFGKFHNVY SVNTPTCSAA EIERLRSEGI FNESEYQMYP PSDNKLNLLD NDEMSPVRDS 421 IDLNQIQILR RDSDEDPDAG EESMELVDLG IHHKCSIRSQ SPIINSTSHL LQPMHKNSCS 481 VRRGSSTLNV SLHG //