LOCUS       DAA09118.1              1170 aa    PRT              PLN 23-JAN-2024
DEFINITION  Saccharomyces cerevisiae S288C Rgt1p protein.
ACCESSION   BK006944-177
PROTEIN_ID  DAA09118.1
SOURCE      Saccharomyces cerevisiae S288C
  ORGANISM  Saccharomyces cerevisiae S288C
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Saccharomycetes; Saccharomycetales; Saccharomycetaceae;
            Saccharomyces.
REFERENCE   1  (bases 1 to 666816)
  AUTHORS   Dujon,B., Alexandraki,D., Andre,B., Ansorge,W., Baladron,V.,
            Ballesta,J.P., Banrevi,A., Bolle,P.A., Bolotin-Fukuhara,M.,
            Bossier,P. et al.
  TITLE     Complete DNA sequence of yeast chromosome XI
  JOURNAL   Nature 369 (6479), 371-378 (1994)
   PUBMED   8196765
REFERENCE   2  (bases 1 to 666816)
  AUTHORS   Goffeau,A., Barrell,B.G., Bussey,H., Davis,R.W., Dujon,B.,
            Feldmann,H., Galibert,F., Hoheisel,J.D., Jacq,C., Johnston,M.,
            Louis,E.J., Mewes,H.W., Murakami,Y., Philippsen,P., Tettelin,H. and
            Oliver,S.G.
  TITLE     Life with 6000 genes
  JOURNAL   Science 274 (5287), 546 (1996)
   PUBMED   8849441
REFERENCE   3  (bases 1 to 666816)
  AUTHORS   Engel,S.R., Wong,E.D., Nash,R.S., Aleksander,S., Alexander,M.,
            Douglass,E., Karra,K., Miyasato,S.R., Simison,M., Skrzypek,M.S.,
            Weng,S. and Cherry,J.M.
  TITLE     New data and collaborations at the Saccharomyces Genome Database:
            updated reference genome, alleles, and the Alliance of Genome
            Resources
  JOURNAL   Genetics 220 (4) (2022)
   PUBMED   34897464
REFERENCE   4  (bases 1 to 666816)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (14-DEC-2009) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
REFERENCE   5  (bases 1 to 666816)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (31-MAR-2011) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Sequence update by submitter
REFERENCE   6  (bases 1 to 666816)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2012) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Protein update by submitter
COMMENT     THIRD PARTY DATABASE: This TPA record uses data from
            DDBJ/EMBL/GenBank entries JF740677.1, Z28001.1, Z28002.1, Z28003.1,
            Z28004.1, Z28005.1, Z28006.1, Z28007.1, Z28008.1, Z28009.1,
            Z28010.1, Z28011.1, Z28012.1, Z28013.1, Z28014.1, Z28015.1,
            Z28016.1, Z28017.1, Z28018.1, Z28019.1, Z28020.1, Z28021.1,
            Z28022.1, Z28023.1, Z28024.1, Z28025.1, Z28026.1, Z28027.1,
            Z28028.1, Z28029.1, Z28031.1, Z28032.1, Z28033.1, Z28034.1,
            Z28035.1, Z28038.1, Z28039.1, Z28040.1, Z28041.1, Z28042.1,
            Z28043.1, Z28044.1, Z28045.1, Z28046.1, Z28047.1, Z28048.1,
            Z28049.1, Z28050.1, Z28051.1, Z28052.1, Z28054.1, Z28055.1,
            Z28056.1, Z28057.1, Z28058.1, Z28059.1, Z28060.1, Z28061.1,
            Z28062.1, Z28063.1, Z28064.1, Z28065.1, Z28066.1, Z28067.1,
            Z28068.1, Z28069.1, Z28070.1, Z28071.1, Z28072.1, Z28073.1,
            Z28074.1, Z28075.1, Z28077.1, Z28078.1, Z28079.1, Z28080.1,
            Z28081.1, Z28082.1, Z28084.1, Z28085.1, Z28086.1, Z28087.1,
            Z28088.1, Z28089.1, Z28090.1, Z28091.1, Z28092.1, Z28093.1,
            Z28094.1, Z28095.1, Z28096.1, Z28097.1, Z28098.1, Z28099.1,
            Z28100.1, Z28101.1, Z28102.1, Z28103.1, Z28104.1, Z28105.1,
            Z28106.1, Z28107.1, Z28108.1, Z28109.1, Z28110.1, Z28111.1,
            Z28113.1, Z28114.1, Z28115.1, Z28117.1, Z28118.1, Z28120.1,
            Z28121.1, Z28122.1, Z28123.1, Z28125.1, Z28126.1, Z28127.1,
            Z28128.1, Z28129.1, Z28130.1, Z28131.1, Z28133.1, Z28134.1,
            Z28135.1, Z28137.1, Z28138.1, Z28139.1, Z28140.1, Z28141.1,
            Z28142.1, Z28143.1, Z28144.1, Z28145.1, Z28146.1, Z28148.1,
            Z28149.1, Z28150.1, Z28151.1, Z28152.1, Z28154.1, Z28155.1,
            Z28156.1, Z28157.1, Z28158.1, Z28159.1, Z28160.1, Z28161.1,
            Z28162.1, Z28163.1, Z28164.1, Z28165.1, Z28166.1, Z28167.1,
            Z28168.1, Z28169.1, Z28171.1, Z28172.1, Z28173.1, Z28174.1,
            Z28175.1, Z28176.1, Z28177.1, Z28179.1, Z28180.1, Z28181.1,
            Z28182.1, Z28183.1, Z28184.1, Z28185.1, Z28186.1, Z28187.1,
            Z28188.1, Z28189.1, Z28190.1, Z28191.1, Z28192.1, Z28193.1,
            Z28194.1, Z28195.1, Z28196.1, Z28197.1, Z28198.1, Z28200.1,
            Z28201.1, Z28202.1, Z28203.1, Z28204.1, Z28205.1, Z28206.1,
            Z28207.1, Z28208.1, Z28209.1, Z28210.1, Z28211.1, Z28212.1,
            Z28213.1, Z28214.1, Z28215.1, Z28216.1, Z28217.1, Z28218.1,
            Z28219.1, Z28220.1, Z28221.1, Z28222.1, Z28223.1, Z28224.1,
            Z28225.1, Z28226.1, Z28227.1, Z28228.1, Z28229.1, Z28230.1,
            Z28231.1, Z28232.1, Z28233.1, Z28234.1, Z28235.1, Z28236.1,
            Z28237.1, Z28238.1, Z28239.1, Z28240.1, Z28241.1, Z28242.1,
            Z28243.1, Z28244.1, Z28245.1, Z28246.1, Z28247.1, Z28248.1,
            Z28249.1, Z28250.1, Z28251.1, Z28252.1, Z28253.1, Z28254.1,
            Z28255.1, Z28256.1, Z28257.1, Z28258.1, Z28259.1, Z28260.1,
            Z28261.1, Z28262.1, Z28263.1, Z28264.1, Z28265.1, Z28266.1,
            Z28267.1, Z28268.1, Z28269.1, Z28270.1, Z28271.1, Z28272.1,
            Z28273.1, Z28274.1, Z28275.1, Z28276.1, Z28277.1, Z28278.1,
            Z28279.1, Z28280.1, Z28281.1, Z28282.1, Z28283.1, Z28284.1,
            Z28285.1, Z28286.1, Z28287.1, Z28288.1, Z28289.1, Z28290.1,
            Z28291.1, Z28292.1, Z28293.1, Z28294.1, Z28295.1, Z28296.1,
            Z28297.1, Z28298.1, Z28299.1, Z28300.1, Z28301.1, Z28302.1,
            Z28303.1, Z28304.1, Z28305.1, Z28306.1, Z28307.1, Z28308.1,
            Z28309.1, Z28310.1, Z28311.1, Z28312.1, Z28313.1, Z28314.1,
            Z28315.1, Z28316.1, Z28317.1, Z28318.1, Z28319.1, Z28320.1,
            Z28321.1, Z28322.1, Z28323.1, Z28324.1, Z28325.1, Z28326.1,
            Z28327.1, Z28328.1, Z28329.1 and Z28330.1
            
            On Apr 18, 2011 this sequence version replaced BK006944.1.
            Chromosome XI sequence was verified by resequencing.  The sequence
            was mapped to the previous GenBank records except for a 500 bp
            region.  That region was determined by sequencing a descendant of
            the S288C strain, AB972, and is present in GenBank as JF740677.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: SGD
            Annotation Status   :: Full Annotation
            Annotation Version  :: R64-4-1
            URL                 :: http://www.yeastgenome.org/
            ##Genome-Annotation-Data-END##
FEATURES             Qualifiers
     source          /organism="Saccharomyces cerevisiae S288C"
                     /mol_type="genomic DNA"
                     /strain="S288C"
                     /db_xref="taxon:559292"
                     /chromosome="XI"
     protein         /gene="RGT1"
                     /locus_tag="YKL038W"
                     /experiment="EXISTENCE:direct assay:GO:0000122 negative
                     regulation of transcription by RNA polymerase II
                     [PMID:12861007]"
                     /experiment="EXISTENCE:direct assay:GO:0000978 RNA
                     polymerase II cis-regulatory region sequence-specific DNA
                     binding [PMID:12861007|PMID:8887670|PMID:12239282]"
                     /experiment="EXISTENCE:direct assay:GO:0001228 DNA-binding
                     transcription activator activity, RNA polymerase
                     II-specific [PMID:8887670]"
                     /experiment="EXISTENCE:direct assay:GO:0003677 DNA binding
                     [PMID:12861007]"
                     /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
                     [PMID:12861007]"
                     /experiment="EXISTENCE:direct assay:GO:0045944 positive
                     regulation of transcription by RNA polymerase II
                     [PMID:8887670]"
                     /experiment="EXISTENCE:genetic interaction:GO:0000122
                     negative regulation of transcription by RNA polymerase II
                     [PMID:8887670]"
                     /experiment="EXISTENCE:genetic interaction:GO:0006006
                     glucose metabolic process [PMID:8013905]"
                     /note="Glucose-responsive transcription factor; regulates
                     expression of several glucose transporter (HXT) genes in
                     response to glucose; binds to promoters and acts both as a
                     transcriptional activator and repressor; recruits
                     Tup1p/Cyc8p to target gene promoters; RGT1 has a paralog,
                     EDS1, that arose from the whole genome duplication"
                     /db_xref="SGD:S000001521"
BEGIN
        1 MNELNTVSTN SSDSTKNGGT SNSPDDMDSA AAASHAIKKR TKASRACDQC RKKKIKCDYK
       61 DEKGVCSNCQ RNGDRCSFDR VPLKRGPSKG YTRSTSHPRT NEIQDHNNSR SYNTFDNSNN
      121 TLNNNTGNSG DNGINSNTVP STPSRSNSVL LPPLTQYIPQ AGGIPPSFQN PAIQSTMPAG
      181 NIGQQQFWKV PYHEFQHQRK GSIDSLQSDI SVRTLNPNEQ LSYNTVQQSP ITNKHTNDSG
      241 NANGSVTGSG SASGSGGYWS FIRTSGLLAP TDDHNGEQTR RSSSIPSLLR NTSNSLLLGG
      301 QPQLPPPQQQ SQPQAHQQKL QQGQNLYSYS QFSQQQPYNP SISSFGQFAA NGFHSRQGSV
      361 ASEAMSPSAP AMFTSTSTNP VNVAQQTQRP QGQQVPQFSS ELDGNKRRQS APVSVTLSTD
      421 RLNGNENNNG EINNNNGSNN SGSSKDTSQH SQESVTTPAA LEASSPGSTP QRSTKKRRKS
      481 YVSKKTKPKR DSSISITSKD SAHPMTTSST IAYGQISDVD LIDTYYEFIH VGFPIIPLNK
      541 TTLTSDLLLV NTQPISNIHE VNSYVILWFR NSLELLVRVA LKQKPGGKFF DNIVGVALSP
      601 SNDNNKAGFT TATARDDAEK TRRDSHNEVQ DTLEVQSVFI AALNECFQKI VDIHPKFREN
      661 NDQISPKIKV IYLSTFILLN YILAFVGYDN SFVLGMSVTI FNEFKLYKLL LFPEPDINDV
      721 KPPVDEEVST GNGNTKTSEF EIGSESAGHM NPSNSPNSMD ENISHYSVLF KRLYVLLSVF
      781 DSLQSCAFGG PKLLNISIQG STERFFSNDL GSKWCLEQSQ LRLKSVLQSL KLGELMSELT
      841 RNRISMNGNR KPGFDITNSS SLLSEYVETQ PLSVAQLFCK LLIGKHNFIN CLLSLYDSEA
      901 GVYSDLTLDL SSKIADSLCS LISIILQVLT LILRLNPTNS IDFNYRPPNP PANNPTVQEG
      961 PSAMGSSPVA GNLSAAPPSE GNPDFYKKLL GLKQDTGTIL SDLCRGIISP FAIAILHEVY
     1021 NITELVKQMP TSLISIMMTA TTTQNTQDTK KSQDLVMKLS NSMNEVVQIT SVLTMIKPFK
     1081 IFEHELNKPI MSLTGGLSST TRNDVMWPKS GQGLRESSVM KTLLDERRTS GTQPTTAPVA
     1141 AEEPRLENVA LENFVSIGWK LLDDSELGWY
//