LOCUS DAA09089.1 959 aa PRT PLN 23-JAN-2024 DEFINITION Saccharomyces cerevisiae S288C FG-nucleoporin NUP100 protein. ACCESSION BK006944-147 PROTEIN_ID DAA09089.1 SOURCE Saccharomyces cerevisiae S288C ORGANISM Saccharomyces cerevisiae S288C Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces. REFERENCE 1 (bases 1 to 666816) AUTHORS Dujon,B., Alexandraki,D., Andre,B., Ansorge,W., Baladron,V., Ballesta,J.P., Banrevi,A., Bolle,P.A., Bolotin-Fukuhara,M., Bossier,P. et al. TITLE Complete DNA sequence of yeast chromosome XI JOURNAL Nature 369 (6479), 371-378 (1994) PUBMED 8196765 REFERENCE 2 (bases 1 to 666816) AUTHORS Goffeau,A., Barrell,B.G., Bussey,H., Davis,R.W., Dujon,B., Feldmann,H., Galibert,F., Hoheisel,J.D., Jacq,C., Johnston,M., Louis,E.J., Mewes,H.W., Murakami,Y., Philippsen,P., Tettelin,H. and Oliver,S.G. TITLE Life with 6000 genes JOURNAL Science 274 (5287), 546 (1996) PUBMED 8849441 REFERENCE 3 (bases 1 to 666816) AUTHORS Engel,S.R., Wong,E.D., Nash,R.S., Aleksander,S., Alexander,M., Douglass,E., Karra,K., Miyasato,S.R., Simison,M., Skrzypek,M.S., Weng,S. and Cherry,J.M. TITLE New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources JOURNAL Genetics 220 (4) (2022) PUBMED 34897464 REFERENCE 4 (bases 1 to 666816) CONSRTM Saccharomyces Genome Database TITLE Direct Submission JOURNAL Submitted (14-DEC-2009) Department of Genetics, Stanford University, Stanford, CA 94305-5120, USA REFERENCE 5 (bases 1 to 666816) CONSRTM Saccharomyces Genome Database TITLE Direct Submission JOURNAL Submitted (31-MAR-2011) Department of Genetics, Stanford University, Stanford, CA 94305-5120, USA REMARK Sequence update by submitter REFERENCE 6 (bases 1 to 666816) CONSRTM Saccharomyces Genome Database TITLE Direct Submission JOURNAL Submitted (04-MAY-2012) Department of Genetics, Stanford University, Stanford, CA 94305-5120, USA REMARK Protein update by submitter COMMENT THIRD PARTY DATABASE: This TPA record uses data from DDBJ/EMBL/GenBank entries JF740677.1, Z28001.1, Z28002.1, Z28003.1, Z28004.1, Z28005.1, Z28006.1, Z28007.1, Z28008.1, Z28009.1, Z28010.1, Z28011.1, Z28012.1, Z28013.1, Z28014.1, Z28015.1, Z28016.1, Z28017.1, Z28018.1, Z28019.1, Z28020.1, Z28021.1, Z28022.1, Z28023.1, Z28024.1, Z28025.1, Z28026.1, Z28027.1, Z28028.1, Z28029.1, Z28031.1, Z28032.1, Z28033.1, Z28034.1, Z28035.1, Z28038.1, Z28039.1, Z28040.1, Z28041.1, Z28042.1, Z28043.1, Z28044.1, Z28045.1, Z28046.1, Z28047.1, Z28048.1, Z28049.1, Z28050.1, Z28051.1, Z28052.1, Z28054.1, Z28055.1, Z28056.1, Z28057.1, Z28058.1, Z28059.1, Z28060.1, Z28061.1, Z28062.1, Z28063.1, Z28064.1, Z28065.1, Z28066.1, Z28067.1, Z28068.1, Z28069.1, Z28070.1, Z28071.1, Z28072.1, Z28073.1, Z28074.1, Z28075.1, Z28077.1, Z28078.1, Z28079.1, Z28080.1, Z28081.1, Z28082.1, Z28084.1, Z28085.1, Z28086.1, Z28087.1, Z28088.1, Z28089.1, Z28090.1, Z28091.1, Z28092.1, Z28093.1, Z28094.1, Z28095.1, Z28096.1, Z28097.1, Z28098.1, Z28099.1, Z28100.1, Z28101.1, Z28102.1, Z28103.1, Z28104.1, Z28105.1, Z28106.1, Z28107.1, Z28108.1, Z28109.1, Z28110.1, Z28111.1, Z28113.1, Z28114.1, Z28115.1, Z28117.1, Z28118.1, Z28120.1, Z28121.1, Z28122.1, Z28123.1, Z28125.1, Z28126.1, Z28127.1, Z28128.1, Z28129.1, Z28130.1, Z28131.1, Z28133.1, Z28134.1, Z28135.1, Z28137.1, Z28138.1, Z28139.1, Z28140.1, Z28141.1, Z28142.1, Z28143.1, Z28144.1, Z28145.1, Z28146.1, Z28148.1, Z28149.1, Z28150.1, Z28151.1, Z28152.1, Z28154.1, Z28155.1, Z28156.1, Z28157.1, Z28158.1, Z28159.1, Z28160.1, Z28161.1, Z28162.1, Z28163.1, Z28164.1, Z28165.1, Z28166.1, Z28167.1, Z28168.1, Z28169.1, Z28171.1, Z28172.1, Z28173.1, Z28174.1, Z28175.1, Z28176.1, Z28177.1, Z28179.1, Z28180.1, Z28181.1, Z28182.1, Z28183.1, Z28184.1, Z28185.1, Z28186.1, Z28187.1, Z28188.1, Z28189.1, Z28190.1, Z28191.1, Z28192.1, Z28193.1, Z28194.1, Z28195.1, Z28196.1, Z28197.1, Z28198.1, Z28200.1, Z28201.1, Z28202.1, Z28203.1, Z28204.1, Z28205.1, Z28206.1, Z28207.1, Z28208.1, Z28209.1, Z28210.1, Z28211.1, Z28212.1, Z28213.1, Z28214.1, Z28215.1, Z28216.1, Z28217.1, Z28218.1, Z28219.1, Z28220.1, Z28221.1, Z28222.1, Z28223.1, Z28224.1, Z28225.1, Z28226.1, Z28227.1, Z28228.1, Z28229.1, Z28230.1, Z28231.1, Z28232.1, Z28233.1, Z28234.1, Z28235.1, Z28236.1, Z28237.1, Z28238.1, Z28239.1, Z28240.1, Z28241.1, Z28242.1, Z28243.1, Z28244.1, Z28245.1, Z28246.1, Z28247.1, Z28248.1, Z28249.1, Z28250.1, Z28251.1, Z28252.1, Z28253.1, Z28254.1, Z28255.1, Z28256.1, Z28257.1, Z28258.1, Z28259.1, Z28260.1, Z28261.1, Z28262.1, Z28263.1, Z28264.1, Z28265.1, Z28266.1, Z28267.1, Z28268.1, Z28269.1, Z28270.1, Z28271.1, Z28272.1, Z28273.1, Z28274.1, Z28275.1, Z28276.1, Z28277.1, Z28278.1, Z28279.1, Z28280.1, Z28281.1, Z28282.1, Z28283.1, Z28284.1, Z28285.1, Z28286.1, Z28287.1, Z28288.1, Z28289.1, Z28290.1, Z28291.1, Z28292.1, Z28293.1, Z28294.1, Z28295.1, Z28296.1, Z28297.1, Z28298.1, Z28299.1, Z28300.1, Z28301.1, Z28302.1, Z28303.1, Z28304.1, Z28305.1, Z28306.1, Z28307.1, Z28308.1, Z28309.1, Z28310.1, Z28311.1, Z28312.1, Z28313.1, Z28314.1, Z28315.1, Z28316.1, Z28317.1, Z28318.1, Z28319.1, Z28320.1, Z28321.1, Z28322.1, Z28323.1, Z28324.1, Z28325.1, Z28326.1, Z28327.1, Z28328.1, Z28329.1 and Z28330.1 On Apr 18, 2011 this sequence version replaced BK006944.1. Chromosome XI sequence was verified by resequencing. The sequence was mapped to the previous GenBank records except for a 500 bp region. That region was determined by sequencing a descendant of the S288C strain, AB972, and is present in GenBank as JF740677. ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-4-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## FEATURES Qualifiers source /organism="Saccharomyces cerevisiae S288C" /mol_type="genomic DNA" /strain="S288C" /db_xref="taxon:559292" /chromosome="XI" protein /gene="NUP100" /locus_tag="YKL068W" /gene_synonym="NSP100" /experiment="EXISTENCE:direct assay:GO:0005643 nuclear pore [PMID:10684247|PMID:8195299]" /experiment="EXISTENCE:direct assay:GO:0017056 structural constituent of nuclear pore [PMID:19098896]" /experiment="EXISTENCE:direct assay:GO:0044613 nuclear pore central transport channel [PMID:18046406]" /experiment="EXISTENCE:genetic interaction:GO:0006606 protein import into nucleus [PMID:20647373]" /experiment="EXISTENCE:genetic interaction:GO:0006607 NLS-bearing protein import into nucleus [PMID:15039779]" /experiment="EXISTENCE:genetic interaction:GO:0017056 structural constituent of nuclear pore [PMID:20647373]" /experiment="EXISTENCE:genetic interaction:GO:0036228 protein localization to nuclear inner membrane [PMID:21659568]" /experiment="EXISTENCE:genetic interaction:GO:0045893 positive regulation of DNA-templated transcription [PMID:15817685]" /experiment="EXISTENCE:mutant phenotype:GO:0000973 post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery [PMID:20932479]" /experiment="EXISTENCE:mutant phenotype:GO:0017056 structural constituent of nuclear pore [PMID:17418788]" /experiment="EXISTENCE:mutant phenotype:GO:0031990 mRNA export from nucleus in response to heat stress [PMID:18258809]" /experiment="EXISTENCE:mutant phenotype:GO:2000238 regulation of tRNA export from nucleus [PMID:27932586]" /experiment="EXISTENCE:physical interaction:GO:0006406 mRNA export from nucleus [PMID:11104765]" /experiment="EXISTENCE:physical interaction:GO:0017056 structural constituent of nuclear pore [PMID:19098896|PMID:12917401|PMID:17803941|PMID:17418788]" /note="FG-nucleoporin component of central core of the nuclear pore complex; contributes directly to nucleocytoplasmic transport and maintenance of the nuclear pore complex (NPC) permeability barrier and is involved in gene tethering at the nuclear periphery; NUP100 has a paralog, NUP116, that arose from the whole genome duplication" /db_xref="SGD:S000001551" BEGIN 1 MFGNNRPMFG GSNLSFGSNT SSFGGQQSQQ PNSLFGNSNN NNNSTSNNAQ SGFGGFTSAA 61 GSNSNSLFGN NNTQNNGAFG QSMGATQNSP FGSLNSSNAS NGNTFGGSSS MGSFGGNTNN 121 AFNNNSNSTN SPFGFNKPNT GGTLFGSQNN NSAGTSSLFG GQSTSTTGTF GNTGSSFGTG 181 LNGNGSNIFG AGNNSQSNTT GSLFGNQQSS AFGTNNQQGS LFGQQSQNTN NAFGNQNQLG 241 GSSFGSKPVG SGSLFGQSNN TLGNTTNNRN GLFGQMNSSN QGSSNSGLFG QNSMNSSTQG 301 VFGQNNNQMQ INGNNNNSLF GKANTFSNSA SGGLFGQNNQ QQGSGLFGQN SQTSGSSGLF 361 GQNNQKQPNT FTQSNTGIGL FGQNNNQQQQ STGLFGAKPA GTTGSLFGGN SSTQPNSLFG 421 TTNVPTSNTQ SQQGNSLFGA TKLTNMPFGG NPTANQSGSG NSLFGTKPAS TTGSLFGNNT 481 ASTTVPSTNG LFGNNANNST STTNTGLFGA KPDSQSKPAL GGGLFGNSNS NSSTIGQNKP 541 VFGGTTQNTG LFGATGTNSS AVGSTGKLFG QNNNTLNVGT QNVPPVNNTT QNALLGTTAV 601 PSLQQAPVTN EQLFSKISIP NSITNPVKAT TSKVNADMKR NSSLTSAYRL APKPLFAPSS 661 NGDAKFQKWG KTLERSDRGS STSNSITDPE SSYLNSNDLL FDPDRRYLKH LVIKNNKNLN 721 VINHNDDEAS KVKLVTFTTE SASKDDQASS SIAASKLTEK AHSPQTDLKD DHDESTPDPQ 781 SKSPNGSTSI PMIENEKISS KVPGLLSNDV TFFKNNYYIS PSIETLGNKS LIELRKINNL 841 VIGHRNYGKV EFLEPVDLLN TPLDTLCGDL VTFGPKSCSI YENCSIKPEK GEGINVRCRV 901 TLYSCFPIDK ETRKPIKNIT HPLLKRSIAK LKENPVYKFE SYDPVTGTYS YTIDHPVLT //