LOCUS       DAA09042.1               216 aa    PRT              PLN 23-JAN-2024
DEFINITION  Saccharomyces cerevisiae S288C Hsp90 cochaperone SBA1 protein.
ACCESSION   BK006944-97
PROTEIN_ID  DAA09042.1
SOURCE      Saccharomyces cerevisiae S288C
  ORGANISM  Saccharomyces cerevisiae S288C
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Saccharomycetes; Saccharomycetales; Saccharomycetaceae;
            Saccharomyces.
REFERENCE   1  (bases 1 to 666816)
  AUTHORS   Dujon,B., Alexandraki,D., Andre,B., Ansorge,W., Baladron,V.,
            Ballesta,J.P., Banrevi,A., Bolle,P.A., Bolotin-Fukuhara,M.,
            Bossier,P. et al.
  TITLE     Complete DNA sequence of yeast chromosome XI
  JOURNAL   Nature 369 (6479), 371-378 (1994)
   PUBMED   8196765
REFERENCE   2  (bases 1 to 666816)
  AUTHORS   Goffeau,A., Barrell,B.G., Bussey,H., Davis,R.W., Dujon,B.,
            Feldmann,H., Galibert,F., Hoheisel,J.D., Jacq,C., Johnston,M.,
            Louis,E.J., Mewes,H.W., Murakami,Y., Philippsen,P., Tettelin,H. and
            Oliver,S.G.
  TITLE     Life with 6000 genes
  JOURNAL   Science 274 (5287), 546 (1996)
   PUBMED   8849441
REFERENCE   3  (bases 1 to 666816)
  AUTHORS   Engel,S.R., Wong,E.D., Nash,R.S., Aleksander,S., Alexander,M.,
            Douglass,E., Karra,K., Miyasato,S.R., Simison,M., Skrzypek,M.S.,
            Weng,S. and Cherry,J.M.
  TITLE     New data and collaborations at the Saccharomyces Genome Database:
            updated reference genome, alleles, and the Alliance of Genome
            Resources
  JOURNAL   Genetics 220 (4) (2022)
   PUBMED   34897464
REFERENCE   4  (bases 1 to 666816)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (14-DEC-2009) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
REFERENCE   5  (bases 1 to 666816)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (31-MAR-2011) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Sequence update by submitter
REFERENCE   6  (bases 1 to 666816)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2012) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Protein update by submitter
COMMENT     THIRD PARTY DATABASE: This TPA record uses data from
            DDBJ/EMBL/GenBank entries JF740677.1, Z28001.1, Z28002.1, Z28003.1,
            Z28004.1, Z28005.1, Z28006.1, Z28007.1, Z28008.1, Z28009.1,
            Z28010.1, Z28011.1, Z28012.1, Z28013.1, Z28014.1, Z28015.1,
            Z28016.1, Z28017.1, Z28018.1, Z28019.1, Z28020.1, Z28021.1,
            Z28022.1, Z28023.1, Z28024.1, Z28025.1, Z28026.1, Z28027.1,
            Z28028.1, Z28029.1, Z28031.1, Z28032.1, Z28033.1, Z28034.1,
            Z28035.1, Z28038.1, Z28039.1, Z28040.1, Z28041.1, Z28042.1,
            Z28043.1, Z28044.1, Z28045.1, Z28046.1, Z28047.1, Z28048.1,
            Z28049.1, Z28050.1, Z28051.1, Z28052.1, Z28054.1, Z28055.1,
            Z28056.1, Z28057.1, Z28058.1, Z28059.1, Z28060.1, Z28061.1,
            Z28062.1, Z28063.1, Z28064.1, Z28065.1, Z28066.1, Z28067.1,
            Z28068.1, Z28069.1, Z28070.1, Z28071.1, Z28072.1, Z28073.1,
            Z28074.1, Z28075.1, Z28077.1, Z28078.1, Z28079.1, Z28080.1,
            Z28081.1, Z28082.1, Z28084.1, Z28085.1, Z28086.1, Z28087.1,
            Z28088.1, Z28089.1, Z28090.1, Z28091.1, Z28092.1, Z28093.1,
            Z28094.1, Z28095.1, Z28096.1, Z28097.1, Z28098.1, Z28099.1,
            Z28100.1, Z28101.1, Z28102.1, Z28103.1, Z28104.1, Z28105.1,
            Z28106.1, Z28107.1, Z28108.1, Z28109.1, Z28110.1, Z28111.1,
            Z28113.1, Z28114.1, Z28115.1, Z28117.1, Z28118.1, Z28120.1,
            Z28121.1, Z28122.1, Z28123.1, Z28125.1, Z28126.1, Z28127.1,
            Z28128.1, Z28129.1, Z28130.1, Z28131.1, Z28133.1, Z28134.1,
            Z28135.1, Z28137.1, Z28138.1, Z28139.1, Z28140.1, Z28141.1,
            Z28142.1, Z28143.1, Z28144.1, Z28145.1, Z28146.1, Z28148.1,
            Z28149.1, Z28150.1, Z28151.1, Z28152.1, Z28154.1, Z28155.1,
            Z28156.1, Z28157.1, Z28158.1, Z28159.1, Z28160.1, Z28161.1,
            Z28162.1, Z28163.1, Z28164.1, Z28165.1, Z28166.1, Z28167.1,
            Z28168.1, Z28169.1, Z28171.1, Z28172.1, Z28173.1, Z28174.1,
            Z28175.1, Z28176.1, Z28177.1, Z28179.1, Z28180.1, Z28181.1,
            Z28182.1, Z28183.1, Z28184.1, Z28185.1, Z28186.1, Z28187.1,
            Z28188.1, Z28189.1, Z28190.1, Z28191.1, Z28192.1, Z28193.1,
            Z28194.1, Z28195.1, Z28196.1, Z28197.1, Z28198.1, Z28200.1,
            Z28201.1, Z28202.1, Z28203.1, Z28204.1, Z28205.1, Z28206.1,
            Z28207.1, Z28208.1, Z28209.1, Z28210.1, Z28211.1, Z28212.1,
            Z28213.1, Z28214.1, Z28215.1, Z28216.1, Z28217.1, Z28218.1,
            Z28219.1, Z28220.1, Z28221.1, Z28222.1, Z28223.1, Z28224.1,
            Z28225.1, Z28226.1, Z28227.1, Z28228.1, Z28229.1, Z28230.1,
            Z28231.1, Z28232.1, Z28233.1, Z28234.1, Z28235.1, Z28236.1,
            Z28237.1, Z28238.1, Z28239.1, Z28240.1, Z28241.1, Z28242.1,
            Z28243.1, Z28244.1, Z28245.1, Z28246.1, Z28247.1, Z28248.1,
            Z28249.1, Z28250.1, Z28251.1, Z28252.1, Z28253.1, Z28254.1,
            Z28255.1, Z28256.1, Z28257.1, Z28258.1, Z28259.1, Z28260.1,
            Z28261.1, Z28262.1, Z28263.1, Z28264.1, Z28265.1, Z28266.1,
            Z28267.1, Z28268.1, Z28269.1, Z28270.1, Z28271.1, Z28272.1,
            Z28273.1, Z28274.1, Z28275.1, Z28276.1, Z28277.1, Z28278.1,
            Z28279.1, Z28280.1, Z28281.1, Z28282.1, Z28283.1, Z28284.1,
            Z28285.1, Z28286.1, Z28287.1, Z28288.1, Z28289.1, Z28290.1,
            Z28291.1, Z28292.1, Z28293.1, Z28294.1, Z28295.1, Z28296.1,
            Z28297.1, Z28298.1, Z28299.1, Z28300.1, Z28301.1, Z28302.1,
            Z28303.1, Z28304.1, Z28305.1, Z28306.1, Z28307.1, Z28308.1,
            Z28309.1, Z28310.1, Z28311.1, Z28312.1, Z28313.1, Z28314.1,
            Z28315.1, Z28316.1, Z28317.1, Z28318.1, Z28319.1, Z28320.1,
            Z28321.1, Z28322.1, Z28323.1, Z28324.1, Z28325.1, Z28326.1,
            Z28327.1, Z28328.1, Z28329.1 and Z28330.1
            
            On Apr 18, 2011 this sequence version replaced BK006944.1.
            Chromosome XI sequence was verified by resequencing.  The sequence
            was mapped to the previous GenBank records except for a 500 bp
            region.  That region was determined by sequencing a descendant of
            the S288C strain, AB972, and is present in GenBank as JF740677.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: SGD
            Annotation Status   :: Full Annotation
            Annotation Version  :: R64-4-1
            URL                 :: http://www.yeastgenome.org/
            ##Genome-Annotation-Data-END##
FEATURES             Qualifiers
     source          /organism="Saccharomyces cerevisiae S288C"
                     /mol_type="genomic DNA"
                     /strain="S288C"
                     /db_xref="taxon:559292"
                     /chromosome="XI"
     protein         /gene="SBA1"
                     /locus_tag="YKL117W"
                     /gene_synonym="CST18"
                     /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
                     [PMID:10207098]"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:10207098]"
                     /experiment="EXISTENCE:direct assay:GO:0032212 positive
                     regulation of telomere maintenance via telomerase
                     [PMID:17389357]"
                     /experiment="EXISTENCE:direct assay:GO:0043392 negative
                     regulation of DNA binding [PMID:23022381]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006457 protein
                     folding [PMID:9632755]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0032212
                     positive regulation of telomere maintenance via telomerase
                     [PMID:17389357]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0051087
                     protein-folding chaperone binding [PMID:9632755]"
                     /experiment="EXISTENCE:physical interaction:GO:0006457
                     protein folding [PMID:9632755]"
                     /experiment="EXISTENCE:physical interaction:GO:0051087
                     protein-folding chaperone binding [PMID:9632755]"
                     /note="Co-chaperone that binds and regulates Hsp90 family
                     chaperones; plays a role in determining prion variants;
                     important for pp60v-src activity in yeast; homologous to
                     the mammalian p23 proteins, and like p23 can regulate
                     telomerase activity; protein abundance increases in
                     response to DNA replication stress"
                     /db_xref="SGD:S000001600"
BEGIN
        1 MSDKVINPQV AWAQRSSTTD PERNYVLITV SIADCDAPEL TIKPSYIELK AQSKPHVGDE
       61 NVHHYQLHID LYKEIIPEKT MHKVANGQHY FLKLYKKDLE SEYWPRLTKE KVKYPYIKTD
      121 FDKWVDEDEQ DEVEAEGNDA AQGMDFSQMM GGAGGAGGAG GMDFSQMMGG AGGAGSPDMA
      181 QLQQLLAQSG GNLDMGDFKE NDEEDEEEEI EPEVKA
//