LOCUS CCU83365.1 1205 aa PRT CON 06-FEB-2024
DEFINITION Caenorhabditis elegans Ras GTPase-activating protein gap-2 protein.
ACCESSION BX284606-2213
PROTEIN_ID CCU83365.1
SOURCE Caenorhabditis elegans
ORGANISM Caenorhabditis elegans
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
Caenorhabditis.
REFERENCE 1 (bases 1 to 17718942)
AUTHORS WormBase.
CONSRTM WormBase Consortium
JOURNAL Submitted (04-FEB-2024) to the INSDC. WormBase Group, European
Bioinformatics Institute, Cambridge, CB10 1SA, UK. Email:
help@wormbase.org
REFERENCE 2 (bases 1 to 17718942)
AUTHORS Sulson J.E., Waterston R.
JOURNAL Submitted (03-MAR-2003) to the INSDC. Nematode Sequencing Project:
Sanger Institute, Hinxton, Cambridge CB10 1SA, UK and The Genome
Institute at Washington University, St. Louis, MO 63110, USA.
REFERENCE 3 (bases 1 to 17718942)
AUTHORS Sulson J.E., Waterston R.
CONSRTM Caenorhabditis elegans Sequencing Consortium
TITLE Genome sequence of the nematode C. elegans: a platform for
investigating biology
JOURNAL Science 282(5396), 2012-2018(1998).
COMMENT Annotated features correspond to WormBase release WS292.
Protein-coding gene structures below are the result of integration
and manual review of the following types of data: ab initio
predictions by Genefinder (P. Green and L. Hillier, pers. comm.);
alignments to published proteins and cDNAs; genome sequence
conservation with other nematodes (e.g. to C. briggsae using WABA:
Genome Res. 2000. 10:1115-1125); sequence features (such as
trans-splice and polyA sites).
Sources of data: large-scale EST projects of Yuji Kohara
(http://www.ddbj.nig.ac.jp/c-elegans/html/CE_INDEX.html); ORFeome
cloning project (http://worfdb.dfci.harvard.edu); RST large-scale
sequencing project (Genome Res. 2009. 19:2334-2342); IST library
(Science. 2004. 303:540-3); RT-PCR EST set (Ewing B. Green P. 2010
Unpublished); UTRome EST data submission (UTRome v1 Mangone M.
Piano F. 2009); TEC-RED data (PNAS 2004. 101:1650-1655); RNA Deep
sequencing data (454 read clusters - Makedonka Mitreva,
unpublished; Illumina sequence data, Genome Res. 2009. 19:657-66);
Numerous data sets from the modENCODE project (Science. 2010.
330:1775-87); Individual C. elegans Nucleotide Database
submissions; Personal communications with C. elegans researchers;
Non-Coding gene structures below are derived using the following
methods and data: ab initio prediction of tRNAs by tRNAscan-SE
(Nucl. Acids. Res., 25, 955-964); integration and appraisal of
miRNAs from miRBase (http://www.mirbase.org); integration and
appraisal of RFAM predictions (rfam.sanger.ac.uk); 21U-RNAs (Cell.
2006. 127:1193-1207); modENCODE data (Science. 2010. 330:1775-87);
manual curation of novel published ncRNAs from the literature.
FEATURES Qualifiers
source /organism="Caenorhabditis elegans"
/chromosome="X"
/strain="Bristol N2"
/mol_type="genomic DNA"
/db_xref="taxon:6239"
protein /transl_table=1
/gene="gap-2"
/locus_tag="CELE_ZK899.8"
/standard_name="ZK899.8k"
/note="Confirmed by transcript evidence"
/db_xref="EnsemblGenomes-Gn:WBGene00001516"
/db_xref="EnsemblGenomes-Tr:ZK899.8k"
/db_xref="GOA:Q8MLZ5"
/db_xref="InterPro:IPR000008"
/db_xref="InterPro:IPR001849"
/db_xref="InterPro:IPR001936"
/db_xref="InterPro:IPR008936"
/db_xref="InterPro:IPR023152"
/db_xref="InterPro:IPR035892"
/db_xref="InterPro:IPR039360"
/db_xref="UniProtKB/Swiss-Prot:Q8MLZ5"
/db_xref="WormBase:WBGene00001516"
intron_pos 51:1 (1/18)
intron_pos 92:0 (2/18)
intron_pos 115:1 (3/18)
intron_pos 175:1 (4/18)
intron_pos 249:0 (5/18)
intron_pos 279:2 (6/18)
intron_pos 337:1 (7/18)
intron_pos 377:2 (8/18)
intron_pos 444:2 (9/18)
intron_pos 489:2 (10/18)
intron_pos 565:0 (11/18)
intron_pos 679:2 (12/18)
intron_pos 792:2 (13/18)
intron_pos 879:2 (14/18)
intron_pos 1004:2 (15/18)
intron_pos 1069:0 (16/18)
intron_pos 1123:2 (17/18)
intron_pos 1176:0 (18/18)
BEGIN
1 MKVIDEKPED EEEEKDSGSK CKTPSSCTKK RVREKEEDLP PICHGWLIVC EGNPTKMMNK
61 EVKLPWHAGY CVFEPRQSTM SCYKQEYPFI AGRMLHRNRT VRMDGDRSAF ARHWGLLPEH
121 YPSPPITGPH TIARSYTRPP KDRLPTKERF FSISRIPSRL TKFSTVRGMS IEFFDAIHDE
181 TNSGGAQVGG ESLDRRGWSG ASTGNRTTLT ASVHNNLMNG RMSSSSHNLS TRLSGSTQNL
241 NQPTNAYGNL LSRPFRSNPL KRTKSVSKME KSLAEANQHS LHRVDASNTP SRDSSLYAQP
301 PARRHLSQPA REGSLRACRS HESLLSSAHS THMIELNEDN RLHPVHPSIF EVPNCFRLAS
361 TYYSCRTPLE RAKWMENLRK TMNPRRDQQR RTENSMLIWI LEAKGLPAKR KYYCEMTLDK
421 TLYAKTSSKA RTDNVFWGEN FEFMMLPKID EVCVSLFRES DSKKKKDTLI GYVTIGIDQL
481 SSRSPVERWY TVNTSHSDSG TSRIASALGG KSSSQESPSL RIKARWQSVH ILPLRAYDNL
541 LETLCYNYLP LCEQLEPVLN VRDKEDLATS LVRVMYKHNL AKEFLCDLIM KEVEKLDNDH
601 LMFRGNTLAT KAMESFMKLV ADDYLDSTLS DFIKTVLQCE DSCEVDPQKL GNVSNSSLEK
661 NRALLMRYVE VAWTKILNNV HQLPKNLRDV FSALRCRLEA QNREALADTL ISSSIFLRFL
721 CPAILSPSLF NLVSEYPSPT NARNLTLIAK TLQNLANFSK FGGKEPHMEF MNEFVDREWH
781 RMKDFLLRIS SESKSGPEKN ADAIVDAGKE LSLIATYLEE AWTPLLQEKN GNKHPLSNVK
841 SVLSELAECK RRSDNGVFHS PMVQQPSSDY ENSPQQHVVP RHENVPAYRS TPPTGQATVL
901 GRSTNRPATH LLTSDDYVLS SAFQTPSLRP GGTRLSDETG TSSSRTSDKT TSSAEIRDDT
961 DSDFELREDR GRGGRNRKRL PRTDASPSSS QQASSGYLSN NPSRSSYSNS SSSSPVERMA
1021 ALSIANPVFG PGPSSGYAIP AEPKEIVYQK RASPPPYDPD VHNYHYQPVY AVPPDCQVSP
1081 RTQATGGVNA QNRLSLPRTN PRASRNSTLL RPSVVNVPDD WDRTSDYWRD RGENNYRSQL
1141 ESQVESQARE IERLMRENIE LKSKMMSSTK TVDSKRSDSG ASEDSYDSLS SLDRPSRQSL
1201 VVVPN
//