LOCUS CCP46644.1 251 aa PRT BCT 27-FEB-2015
DEFINITION Mycobacterium tuberculosis H37Rv Possible acyltransferase protein.
ACCESSION AL123456-3922
PROTEIN_ID CCP46644.1
SOURCE Mycobacterium tuberculosis H37Rv
ORGANISM Mycobacterium tuberculosis H37Rv
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE 1
AUTHORS Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
Barrell B.G.
TITLE Deciphering the biology of Mycobacterium tuberculosis from the
complete genome sequence
JOURNAL Nature 393(6685), 537-544(1998).
PUBMED 9634230
REMARK Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE 2
AUTHORS Camus J.C., Pryor M.J., Medigue C., Cole S.T.
TITLE Re-annotation of the genome sequence of Mycobacterium tuberculosis
H37Rv
JOURNAL Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
PUBMED 12368430
REFERENCE 3
AUTHORS Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
TITLE TubercuList--10 years after
JOURNAL Tuberculosis (Edinb) 91(1), 1-7(2011).
PUBMED 20980199
REFERENCE 4 (bases 1 to 4411529)
AUTHORS Parkhill J.
JOURNAL Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
Mycobacterium tuberculosis sequencing and mapping teams, Sanger
Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
parkhill@sanger.ac.uk
REFERENCE 5 (bases 1 to 4411532)
AUTHORS Lew J.M.
JOURNAL Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
4, SWITZERLAND
COMMENT On or before Feb 1, 2013 this sequence version replaced
gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
gi:38490319, gi:41352785, gi:38490370, gi:41353971.
Note:
This annotation is from the TubercuList website, Release 26, Dec
2012 (URL: http://tuberculist.epfl.ch) (email:
tuberculist@epfl.ch).
FEATURES Qualifiers
source /organism="Mycobacterium tuberculosis H37Rv"
/strain="H37Rv"
/mol_type="genomic DNA"
/db_xref="taxon:83332"
protein /transl_table=11
/locus_tag="Rv3815c"
/note="Rv3815c, (MTCY409.15), len: 251 aa. Possible
acyltransferase, highly similar to Q9CDC0|ML0087 putative
acyltransferase from Mycobacterium leprae (257 aa), FASTA
scores: opt: 845, E(): 2.7e-47, (53.25% identity in 246 aa
overlap). Also highly similar to Q9K3R3|2SCG4.01 putative
acyltransferase from Streptomyces coelicolor (242
aa),FASTA scores: opt: 656, E(): 3.7e-35, (47.85% identity
in 234 aa overlap); and similar to many putative
acyltransferases and hypothetical proteins e.g.
P74498|SLL1848 hypothetical 24.3 KDA protein from
Synechocystis sp. strain PCC 6803 (225 aa) FASTA scores:
opt: 275, E(): 1.2e-10, (34.8% identity in 181 aa
overlap); Q9ZBS1|SC7A1.02 putative acyltransferase from
Streptomyces coelicolor (264 aa), FASTA scores: opt: 266,
E(): 5.2e-10,(29.7% identity in 229 aa overlap);
Q9PNZ5|AAS|CJ0938 putative
2-acylglycerophosphoethanolamine acyltransferase/
acyl-acyl carrier protein synthetase from Campylobacter
jejuni (1170 aa), FASTA scores: opt: 264, E():
2.3e-09,(23.55% identity in 221 aa overlap) (similarity
only with middle section); etc. Also highly similar to
upstream ORF O07809|Rv3814c|MTCY409.16 putative
acyltransferase from Mycobacterium tuberculosis (261 aa),
FASTA scores: opt: 1069, E(): 1e-61, (60.4% identity in
245 aa overlap) ; and downstream ORF
O07807|Rv3816c|MTCY409.14 putative acyltransferase from
Mycobacterium tuberculosis (259 aa) FASTA scores: opt:
847, E(): 2e-47, (55.7% identity in 246 aa overlap). And
similar to O53516|Rv2182c|MTV021.15c hypothetical 27.0 KDA
protein from Mycobacterium tuberculosis (247 aa), FASTA
scores: opt: 237, E(): 3.6e-08, (30.9% identity in 233 aa
overlap)."
/db_xref="EnsemblGenomes-Gn:Rv3815c"
/db_xref="EnsemblGenomes-Tr:CCP46644"
/db_xref="GOA:O07808"
/db_xref="InterPro:IPR002123"
/db_xref="UniProtKB/TrEMBL:O07808"
/experiment="EXISTENCE: identified in proteomics study"
BEGIN
1 MAEPTYRVLE ILAQLLVLAT GTRITYVGEE NVPDQGGAVV AINHTSYVDW LPAALAMHRR
61 RRRMRFMIKA EMQRVRLVNF LIRHTRTIPV DRGAGGSAYA VAVQRLREGE LVGVYPEATI
121 SRSFELKGFK TGAARMAAEA DVPIVPVVVW GAQRIWTKDH PRQIGRAKVP VTVQVGRPLR
181 AAAGIEQTNA ALRESMTALL WQAQERYPHP AGAYWVPRRL GGGAPTLAEA ARMEADEAAA
241 RAASRTPHES R
//