LOCUS CCP46554.1 602 aa PRT BCT 27-FEB-2015
DEFINITION Mycobacterium tuberculosis H37Rv Possible oxidoreductase protein.
ACCESSION AL123456-3832
PROTEIN_ID CCP46554.1
SOURCE Mycobacterium tuberculosis H37Rv
ORGANISM Mycobacterium tuberculosis H37Rv
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE 1
AUTHORS Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
Barrell B.G.
TITLE Deciphering the biology of Mycobacterium tuberculosis from the
complete genome sequence
JOURNAL Nature 393(6685), 537-544(1998).
PUBMED 9634230
REMARK Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE 2
AUTHORS Camus J.C., Pryor M.J., Medigue C., Cole S.T.
TITLE Re-annotation of the genome sequence of Mycobacterium tuberculosis
H37Rv
JOURNAL Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
PUBMED 12368430
REFERENCE 3
AUTHORS Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
TITLE TubercuList--10 years after
JOURNAL Tuberculosis (Edinb) 91(1), 1-7(2011).
PUBMED 20980199
REFERENCE 4 (bases 1 to 4411529)
AUTHORS Parkhill J.
JOURNAL Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
Mycobacterium tuberculosis sequencing and mapping teams, Sanger
Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
parkhill@sanger.ac.uk
REFERENCE 5 (bases 1 to 4411532)
AUTHORS Lew J.M.
JOURNAL Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
4, SWITZERLAND
COMMENT On or before Feb 1, 2013 this sequence version replaced
gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
gi:38490319, gi:41352785, gi:38490370, gi:41353971.
Note:
This annotation is from the TubercuList website, Release 26, Dec
2012 (URL: http://tuberculist.epfl.ch) (email:
tuberculist@epfl.ch).
FEATURES Qualifiers
source /organism="Mycobacterium tuberculosis H37Rv"
/strain="H37Rv"
/mol_type="genomic DNA"
/db_xref="taxon:83332"
protein /transl_table=11
/locus_tag="Rv3727"
/note="Rv3727, (MTV025.075), len: 602 aa. Possible
oxidoreductase, similar to several plants phytoene
dehydrogenases/desaturases e.g. Q9HSE1|CRTI3|VNG0277G
phytoene dehydrogenase from Halobacterium sp. strain NRC-1
(541 aa), FASTA scores: opt: 299, E(): 1.1e-10, (29.85%
identity in 576 aa overlap); Q9FZL6|CITPDS1 phytoene
desaturase from Citrus unshiu (Satsuma orange) (553
aa),FASTA scores: opt: 164, E(): 0.018, (24.2% identity in
434 aa overlap); Q07356|CRTI_ARATH|PDS|AT4G14210|DL3145c
phytoene dehydrogenase precursor from Arabidopsis thaliana
(Mouse-ear cress) (566 aa), FASTA scores: opt: 163, E():
0.021, (23.95% identity in 434 aa overlap); etc.
N-terminal end similar to O69871|SC1C3.29 putative
protoporphyrinogen oxidase (fragment) from Streptomyces
coelicolor (61 aa),FASTA scores: opt: 154, E(): 0.012,
(60.45% identity in 43 aa overlap). The region between aa
155-310 is highly similar to Q49778|B2126_C1_169 from
Mycobacterium leprae (159 aa), FASTA scores: opt: 437,
E(): 1.5e-19, (46.6% identity in 161 aa overlap). And the
region between aa 462-546 is highly similar to the
N-terminal end of Q50003|U1764T from Mycobacterium leprae
(155 aa), FASTA scores: opt: 277, E(): 8.3e-10, (57.65%
identity in 85 aa overlap)."
/db_xref="EnsemblGenomes-Gn:Rv3727"
/db_xref="EnsemblGenomes-Tr:CCP46554"
/db_xref="GOA:O69694"
/db_xref="InterPro:IPR002937"
/db_xref="InterPro:IPR036188"
/db_xref="UniProtKB/TrEMBL:O69694"
/experiment="EXISTENCE: identified in proteomics study"
BEGIN
1 MKPSPADTHV VIAGAGIAGL AAAMILAEAG VRVTLCEAAS EAGGKAKSLR LADGHPTEHS
61 LRVYTDTYQT LLTLFSRIPT EHDRTVLDNL VGVSMVSATA QGVIGRIAAP VALQRRRPTF
121 ARIIGKVVEP PRQLVRILLR GPMVIVGLAQ RGVPATDVLH YLYAHLRLLW MCRERLLAEL
181 GDISYADYLQ LGCKSAQAQE FFSAVPRIYV AARTSAEAAA IAPIVLKGLF RLKSNCPSAL
241 NDAKLPAIMM MDGPTSERMV DPWIRHLTRL GVDIHFNTRV GDLEFDDGRV TALISSDGRR
301 FACDYALLAV PYLTLRELAK SAHVKRYLPQ LTQQHALALE ASNGIQCFLR DLPATWPPFI
361 RPGVVTTHLQ SQWSLVCVLQ GEGFWKNVRL PEGTRYVLSI TWSDVETPGP VFDRPLSECT
421 PDEILTECLT QCGLDKSNVL GWRIDHELKH LDEAEYEKVA SELPPHLVSA PARGQRMVNF
481 SPLTVLMPGA RHRSPGICTS VPNLLLAGEV IYSPDLTLFV PTMEKAACSG YLAARQIMNM
541 VASHAAPLRI DFRDPAPFAV LRRVDRWFWS RRRRPPDRST FATPPTAMPA PSHLTDVDRS
601 AS
//