LOCUS       CCP46468.1               549 aa    PRT              BCT 27-FEB-2015
DEFINITION  Mycobacterium tuberculosis H37Rv Probable conserved transmembrane
            protein protein.
ACCESSION   AL123456-3746
PROTEIN_ID  CCP46468.1
SOURCE      Mycobacterium tuberculosis H37Rv
  ORGANISM  Mycobacterium tuberculosis H37Rv
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
            Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
            Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
            Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
            Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
            Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
            Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
            Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
            Barrell B.G.
  TITLE     Deciphering the biology of Mycobacterium tuberculosis from the
            complete genome sequence
  JOURNAL   Nature 393(6685), 537-544(1998).
   PUBMED   9634230
  REMARK    Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE   2
  AUTHORS   Camus J.C., Pryor M.J., Medigue C., Cole S.T.
  TITLE     Re-annotation of the genome sequence of Mycobacterium tuberculosis
            H37Rv
  JOURNAL   Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
   PUBMED   12368430
REFERENCE   3
  AUTHORS   Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
  TITLE     TubercuList--10 years after
  JOURNAL   Tuberculosis (Edinb) 91(1), 1-7(2011).
   PUBMED   20980199
REFERENCE   4  (bases 1 to 4411529)
  AUTHORS   Parkhill J.
  JOURNAL   Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
            Mycobacterium tuberculosis sequencing and mapping teams, Sanger
            Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
            Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
            rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
            parkhill@sanger.ac.uk
REFERENCE   5  (bases 1 to 4411532)
  AUTHORS   Lew J.M.
  JOURNAL   Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
            Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
            Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
            4, SWITZERLAND
COMMENT     On or before Feb 1, 2013 this sequence version replaced
            gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
            gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
            gi:38490319, gi:41352785, gi:38490370, gi:41353971.
            Note:
            This annotation is from the TubercuList website, Release 26, Dec
            2012 (URL: http://tuberculist.epfl.ch) (email:
            tuberculist@epfl.ch).
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37Rv"
                     /strain="H37Rv"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:83332"
     protein         /transl_table=11
                     /locus_tag="Rv3645"
                     /note="Rv3645, (MTCY15C10.07c), len: 549 aa. Probable
                     conserved transmembrane protein, equivalent, but longer 20
                     aa, to O69547|ML0201|MLCB2548.30 putative membrane protein
                     from Mycobacterium leprae (530 aa), FASTA scores: opt:
                     2958, E(): 1.5e-168, (85.5% identity in 530 aa overlap).
                     Also closely related to several other hypothetical M.
                     tuberculosis proteins, e.g.
                     Q10631|YD18_MYCTU|Rv1318c|MT1359|MTCY130.03c (541 aa)
                     FASTA scores: opt: 1105, E(): 2.7e-58, (39.35% identity in
                     506 aa overlap); Q10633|YD20_MYCTU|Rv1320c|MT1362|MTCY130.
                     05c (567 aa) FASTA scores: opt: 1031, E(): 7.1e-54, (38.1%
                     identity in 509 aa overlap);
                     Q10632|YD19_MYCTU|Rv1319c|MTCY130.04c (535 aa), FASTA
                     scores: opt: 1016, E(): 5.3e-53, (37.1% identity in 531 aa
                     overlap); etc. Also similar at C-terminal end to many
                     adenylate cyclases e.g. O83498|TP0485 from Treponema
                     pallidum (614 aa) FASTA scores: opt: 365, E(): 3.2e-14,
                     (31.55% identity in 317 aa overlap); P94180|CYAA from
                     Anabaena sp. strain PCC 7120 (735 aa), FASTA scores: opt:
                     364, E(): 4.2e-14, (32.75% identity in 229 aa overlap);
                     etc."
                     /db_xref="EnsemblGenomes-Gn:Rv3645"
                     /db_xref="EnsemblGenomes-Tr:CCP46468"
                     /db_xref="GOA:I6X7Z3"
                     /db_xref="InterPro:IPR001054"
                     /db_xref="InterPro:IPR003660"
                     /db_xref="InterPro:IPR029787"
                     /db_xref="UniProtKB/TrEMBL:I6X7Z3"
BEGIN
        1 MDAEAFVGFR QVPAARYGGL MATTAALPRR IHAFVRWVVR TPWPLFSLSM LQSDIIGALF
       61 VLGFLRYGLP PQDNIQLQDL PPVNLLIFVS TVIILFLAGA VVNLKLLMPV FRWQRRDNLL
      121 TEPDPAATEL ARSRALRMPL YRTLISLAVW ATGGGVFILA SWSVAKHAAP VVAVATALGA
      181 TATAIIGYLQ SERVLRPVAV AALRSGVPEN VNAPGVILRL MLAWIPSTGV PLLAIVLAVA
      241 ADKIALLHAT PEALFNPILM MALAALGIGS VSTLLVAMSI ADPLRQLRWA LSEVQRGNYN
      301 AHMQIYDASE LGLLQAGFND MVRELSERQR LRDLFGRYVG EDVARRALER GTELGGQERD
      361 VAVLFVDLVG STQLAATRPP AEVVQLLNEF FRVVVETVAR HGGFVNKFQG DAALAIFGAP
      421 IEHPDGAGAA LSAARELHDE LIPVLGSAEF GIGVSAGRAI AGHIGAQARF EYTVIGDPVN
      481 EAARLTELAK LEDGHVLASA IAVSGALDAE ALCWDVGEVV ELRGRAAPTQ LARPMNLAAP
      541 EEVSSEVRG
//