LOCUS CCP46448.1 323 aa PRT BCT 27-FEB-2015
DEFINITION Mycobacterium tuberculosis H37Rv Possible cell cycle protein
MesJ protein.
ACCESSION AL123456-3726
PROTEIN_ID CCP46448.1
SOURCE Mycobacterium tuberculosis H37Rv
ORGANISM Mycobacterium tuberculosis H37Rv
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE 1
AUTHORS Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
Barrell B.G.
TITLE Deciphering the biology of Mycobacterium tuberculosis from the
complete genome sequence
JOURNAL Nature 393(6685), 537-544(1998).
PUBMED 9634230
REMARK Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE 2
AUTHORS Camus J.C., Pryor M.J., Medigue C., Cole S.T.
TITLE Re-annotation of the genome sequence of Mycobacterium tuberculosis
H37Rv
JOURNAL Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
PUBMED 12368430
REFERENCE 3
AUTHORS Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
TITLE TubercuList--10 years after
JOURNAL Tuberculosis (Edinb) 91(1), 1-7(2011).
PUBMED 20980199
REFERENCE 4 (bases 1 to 4411529)
AUTHORS Parkhill J.
JOURNAL Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
Mycobacterium tuberculosis sequencing and mapping teams, Sanger
Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
parkhill@sanger.ac.uk
REFERENCE 5 (bases 1 to 4411532)
AUTHORS Lew J.M.
JOURNAL Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
4, SWITZERLAND
COMMENT On or before Feb 1, 2013 this sequence version replaced
gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
gi:38490319, gi:41352785, gi:38490370, gi:41353971.
Note:
This annotation is from the TubercuList website, Release 26, Dec
2012 (URL: http://tuberculist.epfl.ch) (email:
tuberculist@epfl.ch).
FEATURES Qualifiers
source /organism="Mycobacterium tuberculosis H37Rv"
/strain="H37Rv"
/mol_type="genomic DNA"
/db_xref="taxon:83332"
protein /transl_table=11
/gene="mesJ"
/locus_tag="Rv3625c"
/note="Rv3625c, (MT3727, MTCY15C10.27), len: 323 aa.
Possible mesJ, cell cycle protein, equivalent to
O69538|Y0C5_MYCLE|ML0213|MLCB2548.18c hypothetical 34.1
KDA protein from Mycobacterium leprae (323 aa) FASTA
scores: opt: 1592, E(): 9e-92, (78.0% identity in 327 aa
overlap). Similar to bacterial hypothetical proteins
Q9X8I6|SCE9.13c from Streptomyces coelicolor (352 aa)
FASTA scores: opt: 705, E(): 1.4e-36, (47.85% identity in
305 aa overlap); and Q9HXZ3|PA3638 from Pseudomonas
aeruginosa (442 aa), FASTA scores: opt: 382, E(): 2e-16,
(40.6% identity in 271 aa overlap). But also similar (or
with similarity) to bacterial cell cycle proteins (MESJ)
e.g. Q9KPX0|VC2242 MESJ protein from Vibrio cholerae (440
aa), FASTA scores: opt: 363, E(): 3e-15, (34.8% identity
in 253 aa overlap); Q9RV23|DR1207 (600 aa) cell cycle
protein MESJ (putative/cytosine deaminase-related protein)
from Deinococcus radiodurans (600 aa), FASTA scores: opt:
310,E(): 7.6e-12, (36.6% identity in 265 aa overlap)
(similar only at the N-terminal end); Q9PFJ8|XF0659 cell
cycle protein from Xylella fastidiosa (437 aa), FASTA
scores: opt: 301, E(): 2.1e-11, (35.05% identity in 271 aa
overlap); P52097|MESJ_ECOLI|B0188 putative cell cycle
protein MESJ from Escherichia coli strain K12(432 aa)
FASTA scores: opt: 299, E(): 2.8e-11, (34.65% identity in
277 aa overlap); etc. Belongs to the UPF0072 (MESJ/YCF62)
family."
/db_xref="EnsemblGenomes-Gn:Rv3625c"
/db_xref="EnsemblGenomes-Tr:CCP46448"
/db_xref="GOA:P9WG53"
/db_xref="InterPro:IPR011063"
/db_xref="InterPro:IPR012094"
/db_xref="InterPro:IPR012795"
/db_xref="InterPro:IPR014729"
/db_xref="InterPro:IPR015262"
/db_xref="UniProtKB/Swiss-Prot:P9WG53"
BEGIN
1 MDRQSAVAQL RAAAEQFARV HLDACDRWSV GLSGGPDSLA LTAVAARLWP TTALIVDHGL
61 QPGSATVAET ARIQAISLGC VDARVLCVQV GAAGGREAAA RSARYSALEE HRDGPVLLAH
121 TLDDQAETVL LGLGRGSGAR SIAGMRPYDP PWCRPLLGVR RSVTHAACRE LGLTAWQDPH
181 NTDRRFTRTR LRTEVLPLLE DVLGGGVAEA LARTATALRE DTDLIDTIAA QALPGAAVAG
241 SRGQELSTSA LTALPDAVRR RVIRGWLLAG GATGLTDRQI RGVDRLVTAW RGQGGVAVGS
301 TLRGQRLVAG RRDGVLVLRR EPV
//