LOCUS       CCP46411.1               207 aa    PRT              BCT 27-FEB-2015
DEFINITION  Mycobacterium tuberculosis H37Rv Beta-carbonic anhydrase
            CanB protein.
ACCESSION   AL123456-3689
PROTEIN_ID  CCP46411.1
SOURCE      Mycobacterium tuberculosis H37Rv
  ORGANISM  Mycobacterium tuberculosis H37Rv
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
            Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
            Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
            Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
            Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
            Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
            Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
            Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
            Barrell B.G.
  TITLE     Deciphering the biology of Mycobacterium tuberculosis from the
            complete genome sequence
  JOURNAL   Nature 393(6685), 537-544(1998).
   PUBMED   9634230
  REMARK    Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE   2
  AUTHORS   Camus J.C., Pryor M.J., Medigue C., Cole S.T.
  TITLE     Re-annotation of the genome sequence of Mycobacterium tuberculosis
            H37Rv
  JOURNAL   Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
   PUBMED   12368430
REFERENCE   3
  AUTHORS   Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
  TITLE     TubercuList--10 years after
  JOURNAL   Tuberculosis (Edinb) 91(1), 1-7(2011).
   PUBMED   20980199
REFERENCE   4  (bases 1 to 4411529)
  AUTHORS   Parkhill J.
  JOURNAL   Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
            Mycobacterium tuberculosis sequencing and mapping teams, Sanger
            Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
            Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
            rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
            parkhill@sanger.ac.uk
REFERENCE   5  (bases 1 to 4411532)
  AUTHORS   Lew J.M.
  JOURNAL   Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
            Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
            Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
            4, SWITZERLAND
COMMENT     On or before Feb 1, 2013 this sequence version replaced
            gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
            gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
            gi:38490319, gi:41352785, gi:38490370, gi:41353971.
            Note:
            This annotation is from the TubercuList website, Release 26, Dec
            2012 (URL: http://tuberculist.epfl.ch) (email:
            tuberculist@epfl.ch).
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37Rv"
                     /strain="H37Rv"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:83332"
     protein         /transl_table=11
                     /gene="canB"
                     /locus_tag="Rv3588c"
                     /note="Rv3588c, (MTV024.06c), len: 207 aa.
                     CanB,Beta-carbonic anhydrase, proven biochemically (See
                     Suarez Covarrubias et al. 2005) similar to others e.g.
                     Q9CBJ1|ML1919 putative carbonic anhydrase from
                     Mycobacterium leprae (213 aa), FASTA scores: opt:
                     1160,E(): 3.1e-66, (84.55% identity in 207 aa overlap).
                     Also similar to many e.g. Q9X903|SCH35.03 from
                     Streptomyces coelicolor (207 aa), FASTA scores: opt: 689,
                     E(): 1.6e-36,(53.85% identity in 195 aa overlap);
                     Q9RS89|DR2238 from Deinococcus radiodurans (264 aa), FASTA
                     scores: opt: 451,E(): 2e-21, (39.7% identity in 189 aa
                     overlap); Q39589|beta-CA1 from Chlamydomonas reinhardtii
                     (267 aa) FASTA scores: opt: 419, E(): 2.1e-19, (36.55%
                     identity in 197 aa overlap); etc. Contains PS00704 and
                     PS00705 Prokaryotic-type carbonic anhydrases signature 1
                     and 2. Belongs to the plant and prokaryotic carbonic
                     anhydrase family."
                     /db_xref="EnsemblGenomes-Gn:Rv3588c"
                     /db_xref="EnsemblGenomes-Tr:CCP46411"
                     /db_xref="GOA:P9WPJ9"
                     /db_xref="InterPro:IPR001765"
                     /db_xref="InterPro:IPR015892"
                     /db_xref="InterPro:IPR036874"
                     /db_xref="PDB:1YM3"
                     /db_xref="PDB:2A5V"
                     /db_xref="UniProtKB/Swiss-Prot:P9WPJ9"
                     /inference="protein motif:PROSITE:PS00705"
                     /inference="protein motif:PROSITE:PS00704"
                     /experiment="EXISTENCE: identified in proteomics study"
BEGIN
        1 MPNTNPVAAW KALKEGNERF VAGRPQHPSQ SVDHRAGLAA GQKPTAVIFG CADSRVAAEI
       61 IFDQGLGDMF VVRTAGHVID SAVLGSIEYA VTVLNVPLIV VLGHDSCGAV NAALAAINDG
      121 TLPGGYVRDV VERVAPSVLL GRRDGLSRVD EFEQRHVHET VAILMARSSA ISERIAGGSL
      181 AIVGVTYQLD DGRAVLRDHI GNIGEEV
//