LOCUS CCP46396.1 711 aa PRT BCT 27-FEB-2015
DEFINITION Mycobacterium tuberculosis H37Rv Probable acyl-CoA dehydrogenase
FadE34 protein.
ACCESSION AL123456-3674
PROTEIN_ID CCP46396.1
SOURCE Mycobacterium tuberculosis H37Rv
ORGANISM Mycobacterium tuberculosis H37Rv
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE 1
AUTHORS Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
Barrell B.G.
TITLE Deciphering the biology of Mycobacterium tuberculosis from the
complete genome sequence
JOURNAL Nature 393(6685), 537-544(1998).
PUBMED 9634230
REMARK Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE 2
AUTHORS Camus J.C., Pryor M.J., Medigue C., Cole S.T.
TITLE Re-annotation of the genome sequence of Mycobacterium tuberculosis
H37Rv
JOURNAL Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
PUBMED 12368430
REFERENCE 3
AUTHORS Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
TITLE TubercuList--10 years after
JOURNAL Tuberculosis (Edinb) 91(1), 1-7(2011).
PUBMED 20980199
REFERENCE 4 (bases 1 to 4411529)
AUTHORS Parkhill J.
JOURNAL Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
Mycobacterium tuberculosis sequencing and mapping teams, Sanger
Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
parkhill@sanger.ac.uk
REFERENCE 5 (bases 1 to 4411532)
AUTHORS Lew J.M.
JOURNAL Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
4, SWITZERLAND
COMMENT On or before Feb 1, 2013 this sequence version replaced
gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
gi:38490319, gi:41352785, gi:38490370, gi:41353971.
Note:
This annotation is from the TubercuList website, Release 26, Dec
2012 (URL: http://tuberculist.epfl.ch) (email:
tuberculist@epfl.ch).
FEATURES Qualifiers
source /organism="Mycobacterium tuberculosis H37Rv"
/strain="H37Rv"
/mol_type="genomic DNA"
/db_xref="taxon:83332"
protein /transl_table=11
/gene="fadE34"
/locus_tag="Rv3573c"
/note="Rv3573c, (MTCY06G11.20c), len: 711 aa. Probable
fadE34, acyl-CoA dehydrogenase, similar to
others,especially in C-terminal half, e.g.
Q9RJX2|SCF37.29c from Streptomyces coelicolor (393 aa)
FASTA scores: opt: 780,E(): 2.8e-39, (44.1% identity in
347 aa overlap); Q9A6N8|CC2049 from Caulobacter crescentus
(401 aa), FASTA scores: opt: 705, E(): 8.7e-35, (41.5%
identity in 342 aa overlap); Q9EX72|MLHC from Rhodococcus
erythropolis (324 aa), FASTA scores: opt: 673, E():
6.1e-33, (42.05% identity in 283 aa overlap);
P41367|ACDM_PIG|ACADM from Sus scrofa (Pig)(421 aa) FASTA
scores: opt: 325, E(): 4.9e- 13, (28.5% identity in 368 aa
overlap); etc. Also similar to others from Mycobacterium
tuberculosis e.g. P95097|FADE22|Rv3061c|MTCY22D7.20 (721
aa), FASTA scores: opt: 1635, E(): 2.7e-90, (42.65%
identity in 729 aa overlap). Could belong to the acyl-CoA
dehydrogenases family."
/db_xref="EnsemblGenomes-Gn:Rv3573c"
/db_xref="EnsemblGenomes-Tr:CCP46396"
/db_xref="GOA:P96855"
/db_xref="InterPro:IPR006091"
/db_xref="InterPro:IPR009075"
/db_xref="InterPro:IPR009100"
/db_xref="InterPro:IPR013786"
/db_xref="InterPro:IPR036250"
/db_xref="InterPro:IPR037069"
/db_xref="UniProtKB/Swiss-Prot:P96855"
/inference="protein motif:PROSITE:PS01156"
/experiment="EXISTENCE: identified in proteomics study"
BEGIN
1 MVATVTDEQS AARELVRGWA RTAASGAAAT AAVRDMEYGF EEGNADAWRP VFAGLAGLGL
61 FGVAVPEDCG GAGGSIEDLC AMVDEAARAL VPGPVATTAV ATLVVSDPKL RSALASGERF
121 AGVAIDGGVQ VDPKTSTASG TVGRVLGGAP GGVVLLPADG NWLLVDTACD EVVVEPLRAT
181 DFSLPLARMV LTSAPVTVLE VSGERVEDLA ATVLAAEAAG VARWTLDTAV AYAKVREQFG
241 KPIGSFQAVK HLCAQMLCRA EQADVAAADA ARAAADSDGT QLSIAAAVAA SIGIDAAKAN
301 AKDCIQVLGG IGCTWEHDAH LYLRRAHGIG GFLGGSGRWL RRVTALTQAG VRRRLGVDLA
361 EVAGLRPEIA AAVAEVAALP EEKRQVALAD TGLLAPHWPA PYGRGASPAE QLLIDQELAA
421 AKVERPDLVI GWWAAPTILE HGTPEQIERF VPATMRGEFL WCQLFSEPGA GSDLASLRTK
481 AVRADGGWLL TGQKVWTSAA HKARWGVCLA RTDPDAPKHK GITYFLVDMT TPGIEIRPLR
541 EITGDSLFNE VFLDNVFVPD EMVVGAVNDG WRLARTTLAN ERVAMATGTA LGNPMEELLK
601 VLGDMELDVA QQDRLGRLIL LAQAGALLDR RIAELAVGGQ DPGAQSSVRK LIGVRYRQAL
661 AEYLMEVSDG GGLVENRAVY DFLNTRCLTI AGGTEQILLT VAAERLLGLP R
//