LOCUS       CCP46378.1               386 aa    PRT              BCT 27-FEB-2015
DEFINITION  Mycobacterium tuberculosis H37Rv Probable acetyl-CoA acetyltransfera
            se FadA6 (acetoacetyl-CoA thiolase) protein.
ACCESSION   AL123456-3656
PROTEIN_ID  CCP46378.1
SOURCE      Mycobacterium tuberculosis H37Rv
  ORGANISM  Mycobacterium tuberculosis H37Rv
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
            Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
            Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
            Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
            Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
            Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
            Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
            Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
            Barrell B.G.
  TITLE     Deciphering the biology of Mycobacterium tuberculosis from the
            complete genome sequence
  JOURNAL   Nature 393(6685), 537-544(1998).
   PUBMED   9634230
  REMARK    Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE   2
  AUTHORS   Camus J.C., Pryor M.J., Medigue C., Cole S.T.
  TITLE     Re-annotation of the genome sequence of Mycobacterium tuberculosis
            H37Rv
  JOURNAL   Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
   PUBMED   12368430
REFERENCE   3
  AUTHORS   Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
  TITLE     TubercuList--10 years after
  JOURNAL   Tuberculosis (Edinb) 91(1), 1-7(2011).
   PUBMED   20980199
REFERENCE   4  (bases 1 to 4411529)
  AUTHORS   Parkhill J.
  JOURNAL   Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
            Mycobacterium tuberculosis sequencing and mapping teams, Sanger
            Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
            Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
            rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
            parkhill@sanger.ac.uk
REFERENCE   5  (bases 1 to 4411532)
  AUTHORS   Lew J.M.
  JOURNAL   Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
            Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
            Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
            4, SWITZERLAND
COMMENT     On or before Feb 1, 2013 this sequence version replaced
            gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
            gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
            gi:38490319, gi:41352785, gi:38490370, gi:41353971.
            Note:
            This annotation is from the TubercuList website, Release 26, Dec
            2012 (URL: http://tuberculist.epfl.ch) (email:
            tuberculist@epfl.ch).
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37Rv"
                     /strain="H37Rv"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:83332"
     protein         /transl_table=11
                     /gene="fadA6"
                     /locus_tag="Rv3556c"
                     /note="Rv3556c, (MTCY06G11.03), len: 386 aa. Probable
                     fadA6, acetyl-CoA acetyltransferase, similar to many e.g.
                     Q9K409|2SCG61.06c from Streptomyces coelicolor (389
                     aa),FASTA scores: opt: 1091, E(): 2.9e-58, (48.1% identity
                     in 399 aa overlap); Q9AAT4|CC0510 from Caulobacter
                     crescentus (391 aa), FASTA scores: opt: 902, E(): 6.6e-47,
                     (40.25% identity in 395 aa overlap); P45359|THL_CLOAB from
                     Clostridium acetobutylicum (392 aa), FASTA scores: opt:
                     872, E(): 4.2e-45, (37.9% identity in 396 aa overlap);
                     Q9I2A8|ATOB|PA2001 from Pseudomonas aeruginosa (393
                     aa),FASTA scores: opt: 872, E(): 4.2e-45, (41.3% identity
                     in 397 aa overlap); etc. Contains PS00737 Thiolases
                     signature 2. Belongs to the thiolase family."
                     /db_xref="EnsemblGenomes-Gn:Rv3556c"
                     /db_xref="EnsemblGenomes-Tr:CCP46378"
                     /db_xref="GOA:I6XHJ3"
                     /db_xref="InterPro:IPR002155"
                     /db_xref="InterPro:IPR016039"
                     /db_xref="InterPro:IPR020613"
                     /db_xref="InterPro:IPR020616"
                     /db_xref="InterPro:IPR020617"
                     /db_xref="UniProtKB/TrEMBL:I6XHJ3"
                     /inference="protein motif:PROSITE:PS00737"
                     /experiment="EXISTENCE: identified in proteomics study"
BEGIN
        1 MTEAYVIDAV RTAVGKRGGA LAGIHPVDLG ALAWRGLLDR TDIDPAAVDD VIAGCVDAIG
       61 GQAGNIARLS WLAAGYPEEV PGVTVDRQCG SSQQAISFGA QAIMSGTADV IVAGGVQNMS
      121 QIPISSAMTV GEQFGFTSPT NESKQWLHRY GDQEISQFRG SELIAEKWNL SREEMERYSL
      181 TSHERAFAAI RAGHFENEII TVETESGPFR VDEGPRESSL EKMAGLQPLV EGGRLTAAMA
      241 SQISDGASAV LLASERAVKD HGLRPRARIH HISARAADPV FMLTGPIPAT RYALDKTGLA
      301 IDDIDTVEIN EAFAPVVMAW LKEIKADPAK VNPNGGAIAL GHPLGATGAK LFTTMLGELE
      361 RIGGRYGLQT MCEGGGTANV TIIERL
//