LOCUS       CCP46370.1               304 aa    PRT              BCT 27-FEB-2015
DEFINITION  Mycobacterium tuberculosis H37Rv Probable short-chain
            type dehydrogenase/reductase protein.
ACCESSION   AL123456-3648
PROTEIN_ID  CCP46370.1
SOURCE      Mycobacterium tuberculosis H37Rv
  ORGANISM  Mycobacterium tuberculosis H37Rv
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
            Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
            Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
            Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
            Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
            Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
            Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
            Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
            Barrell B.G.
  TITLE     Deciphering the biology of Mycobacterium tuberculosis from the
            complete genome sequence
  JOURNAL   Nature 393(6685), 537-544(1998).
   PUBMED   9634230
  REMARK    Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE   2
  AUTHORS   Camus J.C., Pryor M.J., Medigue C., Cole S.T.
  TITLE     Re-annotation of the genome sequence of Mycobacterium tuberculosis
            H37Rv
  JOURNAL   Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
   PUBMED   12368430
REFERENCE   3
  AUTHORS   Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
  TITLE     TubercuList--10 years after
  JOURNAL   Tuberculosis (Edinb) 91(1), 1-7(2011).
   PUBMED   20980199
REFERENCE   4  (bases 1 to 4411529)
  AUTHORS   Parkhill J.
  JOURNAL   Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
            Mycobacterium tuberculosis sequencing and mapping teams, Sanger
            Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
            Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
            rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
            parkhill@sanger.ac.uk
REFERENCE   5  (bases 1 to 4411532)
  AUTHORS   Lew J.M.
  JOURNAL   Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
            Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
            Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
            4, SWITZERLAND
COMMENT     On or before Feb 1, 2013 this sequence version replaced
            gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
            gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
            gi:38490319, gi:41352785, gi:38490370, gi:41353971.
            Note:
            This annotation is from the TubercuList website, Release 26, Dec
            2012 (URL: http://tuberculist.epfl.ch) (email:
            tuberculist@epfl.ch).
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37Rv"
                     /strain="H37Rv"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:83332"
     protein         /transl_table=11
                     /locus_tag="Rv3548c"
                     /note="Rv3548c, (MTCY03C7.08), len: 304 aa. Probable
                     short-chain dehydrogenase/reductase, highly similar to
                     various dehydrogenases/reductases (generally belonging to
                     the SDR family) e.g. Q9I4V1|PA1023 from Pseudomonas
                     aeruginosa (305 aa), FASTA scores: opt: 446, E():
                     1.7e-17,(43.75% identity in 256 aa overlap); Q9A6K0|CC2093
                     from Caulobacter crescentus (301 aa) FASTA scores: opt:
                     437,E(): 5.3e-17, (42.8% identity in 257 aa overlap);
                     Q9HYH8|PA3427 from Pseudomonas aeruginosa (303 aa), FASTA
                     scores: opt: 399, E(): 6.5e-15, (45.5% identity in 257 aa
                     overlap); Q9VXJ0|CG3415 from Drosophila melanogaster
                     (Fruit fly) (598 aa), FASTA scores: opt: 402, E():
                     7.5e-15, (40.7% identity in 285 aa overlap); etc. Also
                     highly similar to O53547|Rv3502c|MTV023.09c putative
                     short-chain type dehydrogenase/reductase from (317 aa)
                     FASTA scores: opt: 739, E(): 1.6e-33, (45.15% identity in
                     310 aa overlap); and other proteins from Mycobacterium
                     tuberculosis. Contains PS00061 Short-chain alcohol
                     dehydrogenase family signature. Belongs to the short-chain
                     dehydrogenases/reductases (SDR) family."
                     /db_xref="EnsemblGenomes-Gn:Rv3548c"
                     /db_xref="EnsemblGenomes-Tr:CCP46370"
                     /db_xref="GOA:P71853"
                     /db_xref="InterPro:IPR002347"
                     /db_xref="InterPro:IPR020904"
                     /db_xref="InterPro:IPR036291"
                     /db_xref="UniProtKB/TrEMBL:P71853"
                     /inference="protein motif:PROSITE:PS00061"
                     /experiment="EXISTENCE: identified in proteomics study"
BEGIN
        1 MGLVDGRVVI VTGAGGGIGR AHALAFAAEG ARVVVNDIGV GLDGSPASGG SAAQDVVDEI
       61 LAAGGQAVAD GSDISDWDQA ANLIQAAVET YGGVDVLVNN AGIVRDRMIA NTSEEEFDAV
      121 IAVHLKGHFA TMRHAASHWR GLSKAGKAPK DIDARIINTS SGAGLQGSVG QGNYSAAKAG
      181 IAALTLVGAA EMRRYGVTVN AIAPAARTRM TETVFAEMMA KPQEGFDAMA PENVSPLVVW
      241 LGSAESRDVT GKVFEVEGGI IRVAEGWAHG PQVDKGVKWD PAELGPVVSD LLAKSRPPVP
      301 VYGA
//