LOCUS       CCP46335.1               218 aa    PRT              BCT 27-FEB-2015
DEFINITION  Mycobacterium tuberculosis H37Rv Probable fatty-acid-CoA
            ligase FadD18 (fragment) (fatty-acid-CoA synthetase) (
            fatty-acid-CoA synthase) protein.
ACCESSION   AL123456-3613
PROTEIN_ID  CCP46335.1
SOURCE      Mycobacterium tuberculosis H37Rv
  ORGANISM  Mycobacterium tuberculosis H37Rv
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
            Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
            Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
            Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
            Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
            Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
            Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
            Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
            Barrell B.G.
  TITLE     Deciphering the biology of Mycobacterium tuberculosis from the
            complete genome sequence
  JOURNAL   Nature 393(6685), 537-544(1998).
   PUBMED   9634230
  REMARK    Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE   2
  AUTHORS   Camus J.C., Pryor M.J., Medigue C., Cole S.T.
  TITLE     Re-annotation of the genome sequence of Mycobacterium tuberculosis
            H37Rv
  JOURNAL   Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
   PUBMED   12368430
REFERENCE   3
  AUTHORS   Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
  TITLE     TubercuList--10 years after
  JOURNAL   Tuberculosis (Edinb) 91(1), 1-7(2011).
   PUBMED   20980199
REFERENCE   4  (bases 1 to 4411529)
  AUTHORS   Parkhill J.
  JOURNAL   Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
            Mycobacterium tuberculosis sequencing and mapping teams, Sanger
            Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
            Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
            rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
            parkhill@sanger.ac.uk
REFERENCE   5  (bases 1 to 4411532)
  AUTHORS   Lew J.M.
  JOURNAL   Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
            Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
            Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
            4, SWITZERLAND
COMMENT     On or before Feb 1, 2013 this sequence version replaced
            gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
            gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
            gi:38490319, gi:41352785, gi:38490370, gi:41353971.
            Note:
            This annotation is from the TubercuList website, Release 26, Dec
            2012 (URL: http://tuberculist.epfl.ch) (email:
            tuberculist@epfl.ch).
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37Rv"
                     /strain="H37Rv"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:83332"
     protein         /transl_table=11
                     /gene="fadD18"
                     /locus_tag="Rv3513c"
                     /note="Rv3513c, (MTV023.20c), len: 218 aa (Start
                     uncertain). Probable fadD18, fatty-acid-CoA synthetase
                     (C-terminal fragment), almost identical to C-terminal end
                     of downstream O53560|FADD19|Rv3515c|MTV023.22c, probably
                     result of partial gene duplication. Also similar at the
                     C-terminus to other fatty-acid-CoA synthetases e.g.
                     Q9EXL2|FADD from Streptomyces griseus (540 aa), FASTA
                     scores: opt: 586, E(): 1.2e-28, (52.45% identity in 185 aa
                     overlap); AAB87139|MIG medium chain acyl-CoA synthetase
                     precursor from Mycobacterium avium (550 aa), FASTA scores:
                     opt: 506, E(): 9.5e-24, (50.0% identity in 150 aa
                     overlap); Q9A7C3|CC1801 putative 4-coumarate--CoA ligase
                     from Caulobacter crescentus (561 aa), FASTA scores: opt:
                     430,E(): 4.4e-19, (45.75% identity in 153 aa overlap);
                     Q9KDT0|BH1131 acid-CoA ligase from Bacillus halodurans
                     (546 aa), FASTA scores: opt: 338, E(): 1.9e-13, (38.05%
                     identity in 142 aa overlap); Q9RTR4|DR1692 long-chain
                     fatty acid--CoA ligase from Deinococcus radiodurans (584
                     aa),FASTA scores: opt: 331, E(): 5.3e-13, (35.15% identity
                     in 145 aa overlap); etc."
                     /db_xref="EnsemblGenomes-Gn:Rv3513c"
                     /db_xref="EnsemblGenomes-Tr:CCP46335"
                     /db_xref="GOA:I6YGC8"
                     /db_xref="InterPro:IPR025110"
                     /db_xref="UniProtKB/TrEMBL:I6YGC8"
BEGIN
        1 MAASLSENLS CHSSNMCRLS GNAATNLERP GEEPPGDRCT RRQAVRPART LAKKGNIPVG
       61 YYKDEKKTAE TFRTINGVRY AIPGDYAQVE EDGTVTMLGR GSVSINSGGE KVYPEEVEAA
      121 LKGHPDVFDA LVVGVPDPRY GQQVAAVVQA RPGCRPSLAE LDSFVRSEIA GYKVPRSLWF
      181 VDEVKRSPAG KPDYRWAKEQ TEARPADDVH AGHVTSGS
//