LOCUS       CCP46319.1               357 aa    PRT              BCT 27-FEB-2015
DEFINITION  Mycobacterium tuberculosis H37Rv Mce-family protein Mce4C protein.
ACCESSION   AL123456-3597
PROTEIN_ID  CCP46319.1
SOURCE      Mycobacterium tuberculosis H37Rv
  ORGANISM  Mycobacterium tuberculosis H37Rv
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
            Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
            Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
            Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
            Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
            Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
            Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
            Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
            Barrell B.G.
  TITLE     Deciphering the biology of Mycobacterium tuberculosis from the
            complete genome sequence
  JOURNAL   Nature 393(6685), 537-544(1998).
   PUBMED   9634230
  REMARK    Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE   2
  AUTHORS   Camus J.C., Pryor M.J., Medigue C., Cole S.T.
  TITLE     Re-annotation of the genome sequence of Mycobacterium tuberculosis
            H37Rv
  JOURNAL   Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
   PUBMED   12368430
REFERENCE   3
  AUTHORS   Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
  TITLE     TubercuList--10 years after
  JOURNAL   Tuberculosis (Edinb) 91(1), 1-7(2011).
   PUBMED   20980199
REFERENCE   4  (bases 1 to 4411529)
  AUTHORS   Parkhill J.
  JOURNAL   Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
            Mycobacterium tuberculosis sequencing and mapping teams, Sanger
            Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
            Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
            rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
            parkhill@sanger.ac.uk
REFERENCE   5  (bases 1 to 4411532)
  AUTHORS   Lew J.M.
  JOURNAL   Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
            Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
            Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
            4, SWITZERLAND
COMMENT     On or before Feb 1, 2013 this sequence version replaced
            gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
            gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
            gi:38490319, gi:41352785, gi:38490370, gi:41353971.
            Note:
            This annotation is from the TubercuList website, Release 26, Dec
            2012 (URL: http://tuberculist.epfl.ch) (email:
            tuberculist@epfl.ch).
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37Rv"
                     /strain="H37Rv"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:83332"
     protein         /transl_table=11
                     /gene="mce4C"
                     /locus_tag="Rv3497c"
                     /note="Rv3497c, (MTV023.04c), len: 357 aa. Mce4C; belongs
                     to 24-membered Mycobacterium tuberculosis Mce protein
                     family (see citations below), highly similar to
                     Mycobacterium tuberculosis proteins
                     O07415|R0171|MTCI28.11|mce1C (515 aa);
                     O07787|Rv0591|MTCY19H5.31|mce2C (481 aa); and
                     O53969|Rv1968|MTV051.06|mce3C (410 aa). Also similar to
                     others e.g. Q9F358|SC8A2.05c putative secreted protein
                     from Streptomyces coelicolor (351 aa), FASTA scores: opt:
                     658,E(): 1.1e-30, (33.95% identity in 318 aa overlap);
                     Q9CD12|MCE1C|ML2591 putative secreted protein from
                     Mycobacterium leprae (519 aa), FASTA scores: opt: 555,
                     E(): 1.2e-24, (28.35% identity in 328 aa overlap); etc.
                     Hydrophobic region at N-terminus. Predicted to be an outer
                     membrane protein (See Song et al., 2008)."
                     /db_xref="EnsemblGenomes-Gn:Rv3497c"
                     /db_xref="EnsemblGenomes-Tr:CCP46319"
                     /db_xref="GOA:I6YGB1"
                     /db_xref="InterPro:IPR003399"
                     /db_xref="InterPro:IPR005693"
                     /db_xref="UniProtKB/TrEMBL:I6YGB1"
                     /experiment="EXISTENCE: identified in proteomics study"
BEGIN
        1 MLNRKPSSKH ERDPLRTGIF GLVLVICVVL IAFGYSGLPF WPQGKTYDAY FTDAGGITPG
       61 NSVYVSGLKV GAVSAVSLAG NSAKVTFSVD RSIVVGDQSL AAIRTDTILG ERSIAVSPAG
      121 SGKSTTIPLS RTTTPYTLNG VLQDLGRNAN DLNRPQFEQA LNVFTQALHD ATPQVRGAVD
      181 GLTSLSRALN RRDEALQGLL AHAKSVTSVL SERAEQVNKL VEDGNQLFAA LDARRAALSA
      241 LISGIDDVAA QISGFVADNR KEFGPALSKL NLVLANLNER RDYITEALKR LPTYATTLGE
      301 VVGSGPGFNV NVYSVLPGPL VATVFDLVFQ PGKLPDSLAD YLRGFIQERW IIRPKSP
//