LOCUS       CCP46318.1               451 aa    PRT              BCT 27-FEB-2015
DEFINITION  Mycobacterium tuberculosis H37Rv Mce-family protein Mce4D protein.
ACCESSION   AL123456-3596
PROTEIN_ID  CCP46318.1
SOURCE      Mycobacterium tuberculosis H37Rv
  ORGANISM  Mycobacterium tuberculosis H37Rv
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
            Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
            Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
            Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
            Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
            Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
            Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
            Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
            Barrell B.G.
  TITLE     Deciphering the biology of Mycobacterium tuberculosis from the
            complete genome sequence
  JOURNAL   Nature 393(6685), 537-544(1998).
   PUBMED   9634230
  REMARK    Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE   2
  AUTHORS   Camus J.C., Pryor M.J., Medigue C., Cole S.T.
  TITLE     Re-annotation of the genome sequence of Mycobacterium tuberculosis
            H37Rv
  JOURNAL   Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
   PUBMED   12368430
REFERENCE   3
  AUTHORS   Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
  TITLE     TubercuList--10 years after
  JOURNAL   Tuberculosis (Edinb) 91(1), 1-7(2011).
   PUBMED   20980199
REFERENCE   4  (bases 1 to 4411529)
  AUTHORS   Parkhill J.
  JOURNAL   Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
            Mycobacterium tuberculosis sequencing and mapping teams, Sanger
            Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
            Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
            rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
            parkhill@sanger.ac.uk
REFERENCE   5  (bases 1 to 4411532)
  AUTHORS   Lew J.M.
  JOURNAL   Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
            Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
            Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
            4, SWITZERLAND
COMMENT     On or before Feb 1, 2013 this sequence version replaced
            gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
            gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
            gi:38490319, gi:41352785, gi:38490370, gi:41353971.
            Note:
            This annotation is from the TubercuList website, Release 26, Dec
            2012 (URL: http://tuberculist.epfl.ch) (email:
            tuberculist@epfl.ch).
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37Rv"
                     /strain="H37Rv"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:83332"
     protein         /transl_table=11
                     /gene="mce4D"
                     /locus_tag="Rv3496c"
                     /note="Rv3496c, (MTV023.03c), len: 451 aa. Mce4D; belongs
                     to 24-membered Mycobacterium tuberculosis Mce protein
                     family (see citations below), highly similar to
                     Mycobacterium tuberculosis proteins
                     O07416|Rv0172|MTCI28.12|mce1D (530 aa);
                     O07786|Rv0592|MTCY19H5.30c|mce2D (508 aa); and
                     O53970|Rv1969|MTV051.07|mce3D (423 aa). Also similar to
                     others e.g. Q9CD11|MCE1D|ML2592 putative secreted protein
                     from Mycobacterium leprae (531 aa), FASTA scores: opt:
                     837,E(): 2.6e-34, (34.55% identity in 446 aa overlap);
                     Q9F359|SC8A2.04c putative secreted protein from
                     Streptomyces coelicolor (337 aa), FASTA scores: opt:
                     606,E(): 4.9e-23, (32.35% identity in 300 aa overlap);
                     etc. Hydrophobic region at N-terminus. Predicted to be an
                     outer membrane protein (See Song et al., 2008)."
                     /db_xref="EnsemblGenomes-Gn:Rv3496c"
                     /db_xref="EnsemblGenomes-Tr:CCP46318"
                     /db_xref="GOA:I6XHD6"
                     /db_xref="InterPro:IPR003399"
                     /db_xref="InterPro:IPR005693"
                     /db_xref="InterPro:IPR024516"
                     /db_xref="UniProtKB/TrEMBL:I6XHD6"
BEGIN
        1 MMGRVAMLTG SRGLRYATVI ALVAALVGGV YVLSSTGNKR TIVGYFTSAV GLYPGDQVRV
       61 LGVPVGEIDM IEPRSSDVKI TMSVSKDVKV PVDVQAVIMS PNLVAARFIQ LTPVYTGGAV
      121 LPDNGRIDLD RTAVPVEWDE VKEGLTRLAA DLSPAAGELQ GPLGAAINQA ADTLDGNGDS
      181 LHNALRELAQ VAGRLGDSRG DIFGTVKNLQ VLVDALSESD EQIVQFAGHV ASVSQVLADS
      241 SANLDQTLGT LNQALSDIRG FLRENNSTLI ETVNQLNDFA QTLSDQSENI EQVLHVAGPG
      301 ITNFYNIYDP AQGTLNGLLS IPNFANPVQF ICGGSFDTAA GPSAPDYYRR AEICRERLGP
      361 VLRRLTVNYP PIMFHPLNTI TAYKGQIIYD TPATEAKSET PVPELTWVPA GGGAPVGNPA
      421 DLQSLLVPPA PGPAPAPPAP GAGPGEHGGG G
//