LOCUS CCP46273.1 262 aa PRT BCT 27-FEB-2015
DEFINITION Mycobacterium tuberculosis H37Rv Probable cutinase precursor
Cut3 protein.
ACCESSION AL123456-3551
PROTEIN_ID CCP46273.1
SOURCE Mycobacterium tuberculosis H37Rv
ORGANISM Mycobacterium tuberculosis H37Rv
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE 1
AUTHORS Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
Barrell B.G.
TITLE Deciphering the biology of Mycobacterium tuberculosis from the
complete genome sequence
JOURNAL Nature 393(6685), 537-544(1998).
PUBMED 9634230
REMARK Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE 2
AUTHORS Camus J.C., Pryor M.J., Medigue C., Cole S.T.
TITLE Re-annotation of the genome sequence of Mycobacterium tuberculosis
H37Rv
JOURNAL Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
PUBMED 12368430
REFERENCE 3
AUTHORS Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
TITLE TubercuList--10 years after
JOURNAL Tuberculosis (Edinb) 91(1), 1-7(2011).
PUBMED 20980199
REFERENCE 4 (bases 1 to 4411529)
AUTHORS Parkhill J.
JOURNAL Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
Mycobacterium tuberculosis sequencing and mapping teams, Sanger
Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
parkhill@sanger.ac.uk
REFERENCE 5 (bases 1 to 4411532)
AUTHORS Lew J.M.
JOURNAL Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
4, SWITZERLAND
COMMENT On or before Feb 1, 2013 this sequence version replaced
gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
gi:38490319, gi:41352785, gi:38490370, gi:41353971.
Note:
This annotation is from the TubercuList website, Release 26, Dec
2012 (URL: http://tuberculist.epfl.ch) (email:
tuberculist@epfl.ch).
FEATURES Qualifiers
source /organism="Mycobacterium tuberculosis H37Rv"
/strain="H37Rv"
/mol_type="genomic DNA"
/db_xref="taxon:83332"
protein /transl_table=11
/gene="cut3"
/gene_synonym="clp3"
/gene_synonym="culp3"
/locus_tag="Rv3451"
/note="Rv3451, (MTCY13E12.04), len: 262 aa. Probable
cut3,cutinase precursor, similar to others e.g. Q9KK87
from Mycobacterium avium (220 aa), FASTA scores: opt: 540,
E(): 3.5e-24, (43.4% identity in 219 aa overlap);
Q00298|CUTI_BOTCI|CUTA from Botrytis cinerea (Botryotinia
fuckeliana) (202 aa), FASTA scores: opt: 214, E():
2e-05,(31.45% identity in 210 aa overlap); Q9Y7G8 from
Pyrenopeziza brassicae (203 aa), FASTA scores: opt:
203,E(): 8.5e-05, (31.05% identity in 190 aa overlap);
P29292|CUTI_ASCRA from Ascochyta rabiei (223 aa), FASTA
scores: opt: 155, E(): 0.054, (31.65% identity in 120 aa
overlap). Similar to other proteins from Mycobacterium
tuberculosis e.g. the downstream ORF
O06319|Rv3452|MTCY13E12.05 hypothetical 23.1 KDA protein
(226 aa), FASTA scores: opt: 775, E(): 1e-37, (58.65%
identity in 220 aa overlap);
Q50664|CUT2_MYCTU|Rv2301|MT2358|MTCY339.08c probable
cutinase precursor (219 aa), FASTA scores: opt: 565, E():
1.3e-25, (44.85% identity in 223 aa overlap);
Q10837|CUT1_MYCTU|Rv1984c|MT2037|MTCY39.35 probable
cutinase precursor (217 aa), FASTA scores: opt: 489, E():
3e-21, (47.05% identity in 221 aa overlap); etc.
Equivalent to AAK47897 from Mycobacterium tuberculosis
strain CDC1551 (247 aa) but longer 15 aa. Contains
cutinase, serine active site motif (PS00155). Belongs to
the cutinase family. Alternative start possible at 3733.
Start changed since first submission (+15 aa)."
/db_xref="EnsemblGenomes-Gn:Rv3451"
/db_xref="EnsemblGenomes-Tr:CCP46273"
/db_xref="GOA:P9WP39"
/db_xref="InterPro:IPR000675"
/db_xref="InterPro:IPR011150"
/db_xref="InterPro:IPR029058"
/db_xref="UniProtKB/Swiss-Prot:P9WP39"
/inference="protein motif:PROSITE:PS00155"
/experiment="EXISTENCE: identified in proteomics study"
BEGIN
1 MNNRPIRLLT SGRAGLGAGA LITAVVLLIA LGAVWTPVAF ADGCPDAEVT FARGTGEPPG
61 IGRVGQAFVD SLRQQTGMEI GVYPVNYAAS RLQLHGGDGA NDAISHIKSM ASSCPNTKLV
121 LGGYSQGATV IDIVAGVPLG SISFGSPLPA AYADNVAAVA VFGNPSNRAG GSLSSLSPLF
181 GSKAIDLCNP TDPICHVGPG NEFSGHIDGY IPTYTTQAAS FVVQRLRAGS VPHLPGSVPQ
241 LPGSVLQMPG TAAPAPESLH GR
//