LOCUS CCP46199.1 296 aa PRT BCT 27-FEB-2015 DEFINITION Mycobacterium tuberculosis H37Rv Diterpene synthase protein. ACCESSION AL123456-3477 PROTEIN_ID CCP46199.1 SOURCE Mycobacterium tuberculosis H37Rv ORGANISM Mycobacterium tuberculosis H37Rv Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C., Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III., Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T., Connor R., Davies R., Devlin K., Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J., Moule S., Murphy L., Oliver K., Osborne J., Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J., Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S., Barrell B.G. TITLE Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence JOURNAL Nature 393(6685), 537-544(1998). PUBMED 9634230 REMARK Erratum:[Nature 1998 Nov 12;396(6707):190] REFERENCE 2 AUTHORS Camus J.C., Pryor M.J., Medigue C., Cole S.T. TITLE Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv JOURNAL Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002). PUBMED 12368430 REFERENCE 3 AUTHORS Lew J.M., Kapopoulou A., Jones L.M., Cole S.T. TITLE TubercuList--10 years after JOURNAL Tuberculosis (Edinb) 91(1), 1-7(2011). PUBMED 20980199 REFERENCE 4 (bases 1 to 4411529) AUTHORS Parkhill J. JOURNAL Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the Mycobacterium tuberculosis sequencing and mapping teams, Sanger Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28 rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail: parkhill@sanger.ac.uk REFERENCE 5 (bases 1 to 4411532) AUTHORS Lew J.M. JOURNAL Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva 4, SWITZERLAND COMMENT On or before Feb 1, 2013 this sequence version replaced gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250, gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756, gi:38490319, gi:41352785, gi:38490370, gi:41353971. Note: This annotation is from the TubercuList website, Release 26, Dec 2012 (URL: http://tuberculist.epfl.ch) (email: tuberculist@epfl.ch). FEATURES Qualifiers source /organism="Mycobacterium tuberculosis H37Rv" /strain="H37Rv" /mol_type="genomic DNA" /db_xref="taxon:83332" protein /transl_table=11 /locus_tag="Rv3378c" /note="Rv3378c, (MTV004.36c), len: 296 aa. Diterpene synthase. Note that this ORF and the downstream ORF MTV004.35c have a significantly lower GC bias than the rest of the genome. This region is a possible MT-complex-specific genomic island (See Becq et al., 2007). Cofactor: Mg2+." /db_xref="EnsemblGenomes-Gn:Rv3378c" /db_xref="EnsemblGenomes-Tr:CCP46199" /db_xref="GOA:P9WJ61" /db_xref="InterPro:IPR036424" /db_xref="PDB:3WQK" /db_xref="PDB:3WQL" /db_xref="PDB:3WQM" /db_xref="PDB:3WQN" /db_xref="PDB:4CMV" /db_xref="PDB:4CMW" /db_xref="PDB:4CMX" /db_xref="PDB:4KT8" /db_xref="UniProtKB/Swiss-Prot:P9WJ61" BEGIN 1 MNLVSEKEFL DLPLVSVAEI VRCRGPKVSV FPFDGTRRWF HLECNPQYDD YQQAALRQSI 61 RILKMLFEHG IETVISPIFS DDLLDRGDRY IVQALEGMAL LANDEEILSF YKEHEVHVLF 121 YGDYKKRLPS TAQGAAVVKS FDDLTISTSS NTEHRLCFGV FGNDAAESVA QFSISWNETH 181 GKPPTRREII EGYYGEYVDK ADMFIGFGRF STFDFPLLSS GKTSLYFTVA PSYYMTETTL 241 RRILYDHIYL RHFRPKPDYS AMSADQLNVL RNRYRAQPDR VFGVGCVHDG IWFAEG //