LOCUS       CCP46187.1               154 aa    PRT              BCT 27-FEB-2015
DEFINITION  Mycobacterium tuberculosis H37Rv Probable tRNA/rRNA methylase
            SpoU (tRNA/rRNA methyltransferase) protein.
ACCESSION   AL123456-3465
PROTEIN_ID  CCP46187.1
SOURCE      Mycobacterium tuberculosis H37Rv
  ORGANISM  Mycobacterium tuberculosis H37Rv
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
            Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
            Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
            Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
            Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
            Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
            Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
            Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
            Barrell B.G.
  TITLE     Deciphering the biology of Mycobacterium tuberculosis from the
            complete genome sequence
  JOURNAL   Nature 393(6685), 537-544(1998).
   PUBMED   9634230
  REMARK    Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE   2
  AUTHORS   Camus J.C., Pryor M.J., Medigue C., Cole S.T.
  TITLE     Re-annotation of the genome sequence of Mycobacterium tuberculosis
            H37Rv
  JOURNAL   Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
   PUBMED   12368430
REFERENCE   3
  AUTHORS   Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
  TITLE     TubercuList--10 years after
  JOURNAL   Tuberculosis (Edinb) 91(1), 1-7(2011).
   PUBMED   20980199
REFERENCE   4  (bases 1 to 4411529)
  AUTHORS   Parkhill J.
  JOURNAL   Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
            Mycobacterium tuberculosis sequencing and mapping teams, Sanger
            Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
            Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
            rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
            parkhill@sanger.ac.uk
REFERENCE   5  (bases 1 to 4411532)
  AUTHORS   Lew J.M.
  JOURNAL   Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
            Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
            Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
            4, SWITZERLAND
COMMENT     On or before Feb 1, 2013 this sequence version replaced
            gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
            gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
            gi:38490319, gi:41352785, gi:38490370, gi:41353971.
            Note:
            This annotation is from the TubercuList website, Release 26, Dec
            2012 (URL: http://tuberculist.epfl.ch) (email:
            tuberculist@epfl.ch).
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37Rv"
                     /strain="H37Rv"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:83332"
     protein         /transl_table=11
                     /gene="spoU"
                     /locus_tag="Rv3366"
                     /note="Rv3366, (MTV004.23), len: 154 aa. Probable
                     spoU,tRNA/rRNA methylase, equivalent to Q9CCU7|ML0419
                     putative tRNA/rRNA methyltransferase from Mycobacterium
                     leprae (158 aa), FASTA scores: opt: 861, E(): 1.2e-50,
                     (83.75% identity in 154 aa overlap); and
                     O07698|MLCL383.24c rRNA methylase from Mycobacterium
                     leprae (169 aa), FASTA scores: opt: 861,E(): 1.3e-50,
                     (83.75% identity in 154 aa overlap). Also highly similar
                     to many members of the spoU family of rRNA methylases e.g.
                     Q9K199|NMB0268 RNA methyltransferase (TRMH family) from
                     Neisseria meningitidis (serogroup B) (154 aa),FASTA
                     scores: opt: 534, E(): 7.6e-29, (50.0% identity in 154 aa
                     overlap); and Q9JSM8|NMA2218 from Neisseria meningitidis
                     (serogroup A) (154 aa), FASTA scores: opt: 526, E():
                     2.6e-28, (49.35% identity in 154 aa overlap);
                     Q9HU57|PA5127 from Pseudomonas aeruginosa (153 aa), FASTA
                     scores: opt: 531, E(): 1.2e-28, (52.95% identity in 151 aa
                     overlap); P33899|YIBK_ECOLI|B3606 from Escherichia coli
                     strain K12 (157 aa), FASTA scores: opt: 511, E():
                     2.6e-27,(49.35% identity in 154 aa overlap); etc. Belongs
                     to the RNA methyltransferase TrmH family."
                     /db_xref="EnsemblGenomes-Gn:Rv3366"
                     /db_xref="EnsemblGenomes-Tr:CCP46187"
                     /db_xref="GOA:O50394"
                     /db_xref="InterPro:IPR001537"
                     /db_xref="InterPro:IPR016914"
                     /db_xref="InterPro:IPR029026"
                     /db_xref="InterPro:IPR029028"
                     /db_xref="UniProtKB/TrEMBL:O50394"
                     /experiment="EXISTENCE: identified in proteomics study"
BEGIN
        1 MFRLLFVSPR IAPNTGNAIR TCAATGCELH LVEPLGFDLS EPKLRRAGLD YHDLASVTVH
       61 ASLAHAWEAL SPARVFAFTA QATTLFTNVG YRAGDVLMFG PEPTGLDEAT LADTHITGQV
      121 RIPMLAGRRS LNLSNAAAVA VYEAWRQHGF AGAV
//