LOCUS CCP46157.1 336 aa PRT BCT 27-FEB-2015
DEFINITION Mycobacterium tuberculosis H37Rv Probable tryptophanyl-
tRNA synthetase TrpS (tryptophan--tRNA ligase) (TRPRS)
(tryptophan translase) protein.
ACCESSION AL123456-3435
PROTEIN_ID CCP46157.1
SOURCE Mycobacterium tuberculosis H37Rv
ORGANISM Mycobacterium tuberculosis H37Rv
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE 1
AUTHORS Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
Barrell B.G.
TITLE Deciphering the biology of Mycobacterium tuberculosis from the
complete genome sequence
JOURNAL Nature 393(6685), 537-544(1998).
PUBMED 9634230
REMARK Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE 2
AUTHORS Camus J.C., Pryor M.J., Medigue C., Cole S.T.
TITLE Re-annotation of the genome sequence of Mycobacterium tuberculosis
H37Rv
JOURNAL Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
PUBMED 12368430
REFERENCE 3
AUTHORS Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
TITLE TubercuList--10 years after
JOURNAL Tuberculosis (Edinb) 91(1), 1-7(2011).
PUBMED 20980199
REFERENCE 4 (bases 1 to 4411529)
AUTHORS Parkhill J.
JOURNAL Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
Mycobacterium tuberculosis sequencing and mapping teams, Sanger
Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
parkhill@sanger.ac.uk
REFERENCE 5 (bases 1 to 4411532)
AUTHORS Lew J.M.
JOURNAL Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
4, SWITZERLAND
COMMENT On or before Feb 1, 2013 this sequence version replaced
gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
gi:38490319, gi:41352785, gi:38490370, gi:41353971.
Note:
This annotation is from the TubercuList website, Release 26, Dec
2012 (URL: http://tuberculist.epfl.ch) (email:
tuberculist@epfl.ch).
FEATURES Qualifiers
source /organism="Mycobacterium tuberculosis H37Rv"
/strain="H37Rv"
/mol_type="genomic DNA"
/db_xref="taxon:83332"
protein /transl_table=11
/gene="trpS"
/locus_tag="Rv3336c"
/note="Rv3336c, (MTV016.36c), len: 336 aa. Probable
trpS,tryptophanyl-tRNA synthetase, equivalent to
Q49901|SYW_MYCLE|TRPS|ML0686|L308_C1_147 tryptophanyl-tRNA
synthetase from Mycobacterium leprae (343 aa), FASTA
scores: opt: 1859, E(): 4.8e-107, (83.75% identity in 339
aa overlap). Also similar to many e.g. Q9KZA7|TRPS2 from
Streptomyces coelicolor (339 aa), FASTA scores: opt:
1359,E(): 2.6e-76, (60.3% identity in 335 aa overlap);
Q9EYY6|TRPS from Klebsiella aerogenes (334 aa), FASTA
scores: opt: 1077, E(): 5.5e-59, (52.15% identity in 328
aa overlap); P00954|SYW_ECOLI|TRPS|B3384 from Escherichia
coli strain K12 (334 aa), FASTA scores: opt: 1074, E():
8.3e-59,(51.85% identity in 328 aa overlap); etc. Contains
PS00178 Aminoacyl-transfer RNA synthetases class-I
signature. Belongs to class-I aminoacyl-tRNA synthetase
family."
/db_xref="EnsemblGenomes-Gn:Rv3336c"
/db_xref="EnsemblGenomes-Tr:CCP46157"
/db_xref="GOA:P9WFT3"
/db_xref="InterPro:IPR001412"
/db_xref="InterPro:IPR002305"
/db_xref="InterPro:IPR002306"
/db_xref="InterPro:IPR014729"
/db_xref="InterPro:IPR024109"
/db_xref="UniProtKB/Swiss-Prot:P9WFT3"
/inference="protein motif:PROSITE:PS00178"
/experiment="EXISTENCE: identified in proteomics study"
BEGIN
1 MSTPTGSRRI FSGVQPTSDS LHLGNALGAV AQWVGLQDDH DAFFCVVDLH AITIPQDPEA
61 LRRRTLITAA QYLALGIDPG RATIFVQSQV PAHTQLAWVL GCFTGFGQAS RMTQFKDKSA
121 RQGSEATTVG LFTYPVLQAA DVLAYDTELV PVGEDQRQHL ELARDVAQRF NSRFPGTLVV
181 PDVLIPKMTA KIYDLQDPTS KMSKSAGTDA GLINLLDDPA LSAKKIRSAV TDSERDIRYD
241 PDVKPGVSNL LNIQSAVTGT DIDVLVDGYA GHGYGDLKKD TAEAVVEFVN PIQARVDELT
301 ADPAELEAVL AAGAQRAHDV ASKTVQRVYD RLGFLL
//