LOCUS CCP46150.1 438 aa PRT BCT 27-FEB-2015 DEFINITION Mycobacterium tuberculosis H37Rv Probable aminotransferase protein. ACCESSION AL123456-3428 PROTEIN_ID CCP46150.1 SOURCE Mycobacterium tuberculosis H37Rv ORGANISM Mycobacterium tuberculosis H37Rv Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C., Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III., Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T., Connor R., Davies R., Devlin K., Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J., Moule S., Murphy L., Oliver K., Osborne J., Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J., Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S., Barrell B.G. TITLE Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence JOURNAL Nature 393(6685), 537-544(1998). PUBMED 9634230 REMARK Erratum:[Nature 1998 Nov 12;396(6707):190] REFERENCE 2 AUTHORS Camus J.C., Pryor M.J., Medigue C., Cole S.T. TITLE Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv JOURNAL Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002). PUBMED 12368430 REFERENCE 3 AUTHORS Lew J.M., Kapopoulou A., Jones L.M., Cole S.T. TITLE TubercuList--10 years after JOURNAL Tuberculosis (Edinb) 91(1), 1-7(2011). PUBMED 20980199 REFERENCE 4 (bases 1 to 4411529) AUTHORS Parkhill J. JOURNAL Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the Mycobacterium tuberculosis sequencing and mapping teams, Sanger Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28 rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail: parkhill@sanger.ac.uk REFERENCE 5 (bases 1 to 4411532) AUTHORS Lew J.M. JOURNAL Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva 4, SWITZERLAND COMMENT On or before Feb 1, 2013 this sequence version replaced gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250, gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756, gi:38490319, gi:41352785, gi:38490370, gi:41353971. Note: This annotation is from the TubercuList website, Release 26, Dec 2012 (URL: http://tuberculist.epfl.ch) (email: tuberculist@epfl.ch). FEATURES Qualifiers source /organism="Mycobacterium tuberculosis H37Rv" /strain="H37Rv" /mol_type="genomic DNA" /db_xref="taxon:83332" protein /transl_table=11 /locus_tag="Rv3329" /note="Rv3329, (MTV016.29), len: 438 aa (start uncertain). Probable aminotransferase, similar to many e.g. O86744|SC6A9.12 from Streptomyces coelicolor (457 aa),FASTA scores: opt: 2120, E(): 5.1e-125, (70.1% identity in 438 aa overlap); Q9I6J2|PA0299 from Pseudomonas aeruginosa (456 aa), FASTA scores: opt: 983, E(): 5.7e-54, (38.1% identity in 425 aa overlap); Q53196|Y4UB_RHISN from Rhizobium sp. strain NGR234 plasmid sym pNGR234a (467 aa),FASTA scores: opt: 971, E(): 3.3e-53, (39.25% identity in 438 aa overlap); P33189|YHXA_BACSU from Bacillus subtilis (450 aa), FASTA scores: opt: 933, E(): 7.5e-51, (40.25% identity in 435 aa overlap); etc. Equivalent to AAK47775 from Mycobacterium tuberculosis strain CDC1551 (466 aa) but shorter 28 aa. Cofactor: pyridoxal phosphate. Could belong to class-III of pyridoxal-phosphate-dependent aminotransferases." /db_xref="EnsemblGenomes-Gn:Rv3329" /db_xref="EnsemblGenomes-Tr:CCP46150" /db_xref="GOA:O53379" /db_xref="InterPro:IPR005814" /db_xref="InterPro:IPR015421" /db_xref="InterPro:IPR015422" /db_xref="InterPro:IPR015424" /db_xref="UniProtKB/Swiss-Prot:O53379" BEGIN 1 MHFARHGAGI QHPVIVRGDG VTIFDDRGKS YLDALSGLFV VQVGYGRAEL AEAAARQAGT 61 LGYFPLWGYA TPPAIELAER LARYAPGDLN RVFFTSGGTE AVETAWKVAK QYFKLTGKPG 121 KQKVISRSIA YHGTTQGALA ITGLPLFKAP FEPLTPGGFR VPNTNFYRAP LHTDLKEFGR 181 WAADRIAEAI EFEGPDTVAA VFLEPVQNAG GCIPAPPGYF ERVREICDRY DVLLVSDEVI 241 CAFGRIGSMF ACEDLGYVPD MITCAKGLTS GYSPLGAMIA SDRLFEPFND GETMFAHGYT 301 FGGHPVSAAV GLANLDIFER EGLSDHVKRN SPALRATLEK LYDLPIVGDI RGEGYFFGIE 361 LVKDQATKQT FTDDERARLL GQVSAALFEA GLYCRTDDRG DPVVQVAPPL ISGQPEFDTI 421 ETILRSVLTD TGRKYLHL //